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23 Cards in this Set
- Front
- Back
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4 types of nonshared enviro
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differential parent treatment, differential sib treatment, differential peer groups, life events
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which factor is important throughout development?
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nonshared
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Why do we care about IDing genes for EDs?
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could aid prevention and treatment
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Genes are linked if...
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they don’t get separated during crossover
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in linkage studies, look at ____ to find ____
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at relatives who are both affected, hot spots on chromosomes
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general AN findings in linkage studies
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trend on chromosome 4
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RAN findings in linkage studies
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hot spot on chromosome 1
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prevalence of RAN
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.5
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BN linkage findings
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Chromosome 10 showed strongest evidence for linkage
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where are obesity genes located?
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chromosome 10
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in association studies, look at...
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...specific genes for traits
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3 gene findings for assoc studies
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Serotonin, brain derived neurotrophic factor (BDNF), and estrogen genes
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high serotonin is correlated with
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anxiety (trait level) and decreased food intake
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low serotonin is correlated with
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impulsivity
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on 5HT2a receptor gene...
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higher frequency of A in individuals with eating pathology (AN, particularly RAN)
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alleles of 5HT2a receptor gene
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A, G
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what is BDNF involved in?
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growth, differentiation, and survival of new neurons AND food intake
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_____ allele increased in individuals with eating pathology (RAN)
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Met66
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high estrogen assoc with
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decreased food intake, anxiety
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effects of removing ovaries
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increased food intake
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gene assoc with both AN and BN
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Estrogen receptor beta gene
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what 2 systems are regulated by estrogen?
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serotonin, bdnf
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cytogenetics
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study of chromosomes
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