Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
20 Cards in this Set
- Front
- Back
|
if there is an association,
|
there is a higher freq of a specific allele in people with the disease
|
|
|
if there is a linkage,
|
two genes are inherited together in people with the disease
|
|
|
in brothers, if one x-linked gene is expressed...
|
all brothers wil either express the gene or all will not express the gene
|
|
|
lilenfeld found that family members of AN/BN probands are ___ more likely to have AN/BN
|
7-12x
|
|
|
3 types of quantitative studies
|
family, adoption, twin studies
|
|
|
model fitting analysis is a refinement of...
|
twin studies
|
|
|
heritability estimate
|
proportion of individual differences within a population that is due to genes
|
|
|
heritability estimate EQ
|
2(rMZ-rDZ)
|
|
|
if rMZ is twice rDZ
|
genetic effect
|
|
|
if rMZ = rDZ
|
shared
|
|
|
if rMZ < 1
|
nonshared
|
|
|
if rMZ = rDZ = 1
|
entirely shared
|
|
|
2 types of molecular studies
|
linkage, association
|
|
|
look directly at genomes/genes
|
molecular studies
|
|
|
examine patterns of relatedness
|
quantitative studies
|
|
|
find hot spots
|
linkage studies
|
|
|
examine specific gene
|
association studies
|
|
|
linkage is when...
|
...share forms of the marker (alleles) at greater than chance levels
|
|
|
lilenfeld found that relatives of people with AN and BN had increased risk for
|
MDD and OCD
|
|
|
lilenfeld found that the only diseases that showed transmission were
|
AN and OCPD
|
