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145 Cards in this Set

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Define stroke volume
Stroke volume is the amount of blood ejected in a single contraction.
The formula for stroke volume
SV = EDV - ESV

**Use biplane simpson to measure
The normal range for SV
Stroke Volume = 70-100 cc
3 ways to measure Stroke volume
1) m-mode
2) biplane simpson
3) Doppler (CSA x VTI)
Define cardiac output
The total amount of blood ejected per minute
Formula for cardiac output
CO = stroke volume x HR
The normal range for cardiac output
CO = 4-8 liter/min
The formula for cardiac index
CI = CO/BSA
Normal range for Cardiac index
CI = 2.4 to 4.2 liters/min/m2
Define ejection fraction
The % of blood ejected from a chamber with each contraction
The normal range for Ejection Fraction
EF = 55-75%
The formula for ejection fraction
EF = SV/EDV x 100
or
EF = EDV-ESV/EDV (all cubed)
5 ways to measure ejection fraction
1) M-mode LV
2) 2d PLAX
3) Biplane simpson
4) M-mode EPSS
5) eye ball it
Define afterload
The tension or arterial pressure agaianst which the ventricle must contract
An EPSS of 1 - 2 cm (high) will have what EF?

Greater than 2 cm?
1-2 cm = 30-50% EF
> 2 cm = less than 30% EF
What is the effect of increased afterload on the velocity of cardiac fiber shortening?
Slower contraction due to more resistence.

Ventricles must use more force to contract resulting on thickening of the myocardium (concentric hypertrophy) eventually leading to the muscle wearing out.
What is the effect of afterload on the cardiac performance?
Performance will decrease.

Volume & pressure overloads are linked so an increase in one will lead to increase in the other and back-up (congestion) occurs
What heart diseases cause increase afterload
1) Stenosis
2) hypertension
3) coarctation of aorta
The central venous pressure reflects the pressure in the _____
Right atrium
Define preload
The volume of blood in the Left Ventricle @ end-diastole
- The amount of blood available to eject
- The maximum stretch of the muscle fibers @ end-diastole
What is the effect of increased preload on the force of ventricular contraction?
Within the physiological limits, the longer the fiber length (more stretch) the stronger the contraction.
Pass the physiological limit, it leads to dilation of LV and heart failure
What heart diseases cause increase preload?
1) regurge
2)shunt
3) Volume overload
What is the predominant echo finding associated with increased afterload?
Constrictive LVH
- thickening of the wall
What is the predominant echo finding associated with increased preload?
Within physiological limits - increased contractility

Pass physiological limit - ventricular dilation
Describe the blood flow in the systemic circulation
LA-->LV-->AoV--> all arteries/veins throughout body --> back through IVC/SVC/CS --> RA
What is the frank starlings law of the heart?
Preload increases = contractility increases

Adding more volume to the LV wall and the wall will stretch more (relax more) and contract longer and stronger.

"LENGTH-TENSION RELATIONSHIP"
What is the effect of increased interval between each heart beat?
LONGER interval = STRONGER contraction
The longer time between contractions (longer T wave) will result in stronger contraction
The peak velocity and peak pressure gradient of post premature ventricular contraction (PVC) with a compensatory pause will __________
Increase the strength of the next contraction
The strength of ventricular contraction in patient with sinus bradycardia will ____
INCREASE
3 factors affecting stroke volume
1) preload
2) afterload
3) Contractility
If the SV is 70 ml, HR is 90 beat/min. What is CO?
CO = SV X HR

70 x 90 = 630 ml/min
The left ventricular stroke volume is ____ to the right ventricular stroke volume
EQUAL
During the cardiac cycle, what VALVE event most closely follows the T-wave on ECG?
The AV valves opening after IVRT
What causes the heart valves to open and close?
Pressure differences
At what times of the cardiac cycle will the Mitral valve be closed?
1) Systole
2) IVRT
3) IVCT
At what time during the cardiac cycle will the tricuspid valve be open?
Diastole
At what times during the cardiac cycle will the Aortic valve be closed?
1) Diastole
2) IVRT
3) IVCT
At what time of the cardiac cycle will the pulmonic valve be open?
Systole
Define IVRT
Isovolmetric relaxation time ... start of diastole. End T- Wave. No change in volume only in pressure. Before RELAXATION TIME
Define IVCT
Isovolmetric Contraction Time ... All valves closed at the start of systole. No change in volume only in pressure. Before CONTRACTION TIME
What are the phases of ventricular diastole?
IVRT - all valves closed
Rapid Filling/early - AV valves open
Diastasis/mid - partial closure of MV
Atrial kick - re-opening of MV with atrial contraction
What % of blood is ejected in the different stages of Diastole?
IVRT = 0%
Rapid filling/early = 70%
Diastasis = 0 - 10 %
Atrial kick/late = 20-30%
Which component of the ECG tracing represents ventricular systole?
QRS and T waves
Define first heart sound
Closure of the AV valves "lubb"
Define 2nd heart sound
Closure of the semi-lunar Valves "dubb"
On ECG where does diastole start and end?
Starts at end of T wave and ends at Q
Flow from pulmonary veins to LA occurs when ....
Diastole and systole ... constant flow
Flow from IVC SVC to RA occurs ....
Diastole and systole ... constant flow
Filling of the coronary arteries with blood occurs during ....
Diastole
Myocardial blood flow occurs during ...
Diastole
The pulmonary capillary wedge pressure represents the pressure in the ___
Left atrium
Normal range for EPSS
EPSS = 0.2 to 0.7 cm
Normal range for MV D-E excursion
MV D- E = 1.8 to 2.8 cm
Normal range for MV E-F
MV E-F = 7 to 15 cm/sec
Normal range for LA (end S)
LA 2.7 to 4 cm
Normal range for ACS (early systole)
ACS = 1.5 to 2.6 cm
Normal range for AO Root (end D)
AoR = 2 to 3.7 cm
Normal range for RVID d
RVIDd = 1.9 to 2.6 cm
Normal range for LVIDd
LVIDd = 3.9 to 5.9 cm
Normal range for LVIDs
LVIDS = 2 to 3.8
Normal range for IVSd
IVSd = 0.6 to 1 cm
Normal range for LVPWd
LVPWd = 0.6 to 1 cm
When do the Mitral valve and tricuspid valve open?
After IVRT
On ECG after T-wave
When do the Aov and PV open?
After IVCT
On ECG after R-wave
When do MV and TV close?
Before IVCT
When do AoV and PV close
Before IVRT
What causes changes in atrium pressure?
The constant filling from pulmonary system
What causes changes in ventricular pressure?
contraction and relaxation of the ventricles
On ECG the IVCT is represented by
IVCt = QRS
On ECG the IVRT is represented by
IVRT = Mid-T wave
When is Systole on ECG
QRS and T waves
When is diastole on ECG
End T wave to Q (includes P wave)
SV, CO, CI, EF and FS all measure what?
Systolic function of left ventricle
Define Fractional shortening
The percentage of shortening in left ventricle in systole
Normal range of Fractional shortening?
FS = 25-45%
What does the cardiac cycle consist of?
(refer to wiggers diagrahm)
- movement of blood flow
- opening/closing of valves
- pressure changes
- Volume changes
What does the P wave represent
Atrial contraction/ late diastole
What does the end T wave represent
IVRT/start of diastole
What does the Q wave represent
End of diastole/beginning of systole
What does QRS represent
IVCT/beginning of systole
What does the ST segment represent
Ventricular contraction/ejection
On ECG when does the AoV open?
After the R wave
What causes 3rd heart sound?
Oscillation of ventricle walls due to increased atrial pressure
What causes the 4th heart sound?
Atrial kick over a stiff ventricle
What areas is auscultation heard on the chest
1) Aortic
2) Pulmonic
3) Mitral
4) Tricuspid
Where is aortic auscultation heard?
2nd intercostal space @ RT sternal border
Where is pulmonic auscultation heard?
2nd intercostal space @ LT sternal border
Where is tricuspid auscultation heard?
LT lower sternal border
Where is mitral auscultation heard?
apex
What heart murmur is faintest?
Grade 1
What grade heart murmur is moderate?
Grade 3
What grade heart murmur is loudest?
Grade 6
What is a heart murmur?
indicates valve disease/turbulent flow
What causes heart murmurs?
1) stenosis
2) regurge
3) shunt
What is a Thrill? and when is it heard?
A tremor or vibration felt of palpation. Heard in grade 4, 5, 6 heart murmurs
Left heart failure
The heart does not adequately circulate blood to systemic system. Due to pressure overload or volume overload
What grade heart murmur is moderate?
Grade 3
Effects of left heart failure
blood backs up to lungs and patient has shortness of breath
What grade heart murmur is loudest?
Grade 6
Right heart failure
The heard does not adequately circulate blood to the pulmonic system. Can be due to volume overload or regurge in TV or PV.
What is a heart murmur?
indicates valve disease/turbulent flow
Effects of right heart failure
Can lead to systemic edema, back up of blood in liver and lower extremities
What causes heart murmurs?
1) stenosis
2) regurge
3) shunt
Valves open and close related to change in ....
PRESSURE
What is a Thrill? and when is it heard?
A tremor or vibration felt of palpation. Heard in grade 4, 5, 6 heart murmurs
Left heart failure
The heart does not adequately circulate blood to systemic system. Due to pressure overload or volume overload
Effects of left heart failure
blood backs up to lungs and patient has shortness of breath
Right heart failure
The heard does not adequately circulate blood to the pulmonic system. Can be due to volume overload or regurge in TV or PV.
Effects of right heart failure
Can lead to systemic edema, back up of blood in liver and lower extremities
Valves open and close related to change in ....
PRESSURE
When are all 4 valves closed?
During IVRT and IVCT
During IVRT and IVCT, no change in ______ occurs, only change in _______
No change in volume, only change in pressure
MV opens when....
LA pressure exceeds LV
Aov opens when ...
LV pressure exceeds AoR
TV opens when
RA pressure exceeds RV
PV opens when
RV pressure exceeds Pulmonic trunk
MV closes when
LV pressure exceeds LA
AoV closes when
AoR pressure increases LV
TV closes when
RV pressure exceeds RA
PV closes when
Pulmonic truck pressure exceeds RV
The fetal heart tube appears by the end of week
Three
The fetal heart tube begins to beat by day
23
The heart is completely formed by week
Seven (42 days)
The heart tube loops _______ at day ____
The heart tube loops ANTERIORLY and RIGHTWARD at day 22
The looping of the heart tubes creates the ________
Bulboventricular loop
The bulboventricular loop forms the ____
Great arteries and ventricles
The 7 distinct section fo the heart tube (in cephalad order)
1) sinus venosus
2) primitive atria
3) AV canal
4) primitive ventricle
5) bulbus cordis
6) truncus arteriosus
7) aortic sac and arches
The sinus venosus consists of 2 horns, right and left, and contributes to the formation of _______
The IVC, SVC, CS and posterior wall of atrium
The septum primum, septum secundum, and foramen ovale are associated with the developement of the _____
Interatrial septum IAS
The AV canal is a large communication between the __________ and ________
Primitive atria and primitive ventricle
The ________ divides the AV canal into right and left AV orificies
endocardial cushions
The endocardial cushions contribute to the closure of the ostium primum and the membranous septum and form the ______ and ______ leaflets
Anterior mitral valve leaflet and septal tricuspid leaflet
The primitive ventricle is usually a morphologic ______
Left ventricle
The bulbos cordis contributes to the formation of the _____
RT ventricle, both ventrical out-flow tracts and the truncus arteriosus
The truncus arteriosus contributes to the formation of the _____
Aortic and pulmonary trunks
How many paired aortic arches?
6
Which aortic arches disappear?
#1, 2 and 5
The 3rd aortic arch contribules to the formation of _____
Internal Carotid artery
The 4th aortic arch contribules to the formation of the ______
aortic arch
The 6th aortic arch contributes to the formation of _______
Left and RT pulmonary artery and ductus arteriosus
The aortic sac contributes to the formation of the ______
Ascending aorta
The central portion of the interatrial septum is calle dthe _________
foramen ovale
What 5 things occur after birth?
1) systemic pressure increases
2) pulmonary vascular resistence decreases
3) RT heart pressure decreases
4) LT heart pressure increases
5) 3 channels of communication in fetal circulation close ...
a) ductus arteriosus
b) foramen ovale
c) ductus venosus
The foramen ovale closes after birth due to the increase in left heart pressure and becomes the ______
Fossa ovallus
The ductus arteriosus closes after birth due to increased systemic pressure and becomes the _______
ligamentum arteriosum