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10 Cards in this Set
- Front
- Back
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What is the frequency of early pregnancy loss (<13 weeks) among different age groups? |
<35 10% >=35 20% >=40 40% >=45 80% |
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How to diagnose early pregnancy loss using ultrasound? |
- CRL >= 5 mm w/o cardiac activity (5.3 mm 100% specificity; radiologists' society says 7 mm) - Empty gestational sac >=16 mm (21 mm 100% specificity; radiologists' society says 25 mm) - Empty gestational sac still empty seven days later (radiologists' society says 14 days later) |
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Expectant mgmt of early pregnancy loss? Success statistics? |
80% of early pregnancy loss will spontaneously expel -- may take up to eight weeks to resolve |
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Medical mgmt of early pregnancy loss? Regimen and success statistics? Follow-up? |
- Regimen: 800 mcg misoprostol vaginally, can repeat once within seven days (at least three hours later). - Must confirm complete expulsion on sonogram: absence of gestational sac, endometrial lining <30 mm - 70% expulsion within three days - 84% expulsion after second dose |
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Is there a benefit to adding mifepristone to misoprostol regimen of medical mgmt for early pregnancy loss? |
No. |
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In cases of incomplete abortion, do the rates of evacuation in expectant and medical (misoprostol) mgmt differ? |
No. |
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What to give Rh negative women after early pregnancy loss? |
Give 50 mcg RhoGAM immediately after suction d&c or within 72 hours of diagnosis of pregnancy loss if planning expectant or medical mgmt. |
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Is there an effective intervention to prevent early pregnancy loss? |
Women w/ three prior early pregnancy losses may benefit from progesterone therapy in the first trimester. |
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What is misoprostol? |
A prostaglandin E1 analogue |
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What is mifepristone? |
A norethindrone derivative that acts as an anti-progestin. It causes decidual necrosis, cervical softening, |
