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12 Cards in this Set
- Front
- Back
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Ultra-Rapid Onset
Short DOA |
1. Insulin lispro (Humalog)
2. Insulin aspart (Novolog) 3. insulin glulisine (Apidra) |
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Rapid Onset
Short DOA |
Regular Insulin (crystalline zinc)
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Intermediate Onset
Intermediate DOA |
1. Neutral Protamine Hagedorn*
(phosphate buffer) 2. Lente (acetate buffer) –has been discontinued |
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Intermediate Onset
Extended DOA |
Insulin glargine (Lantus)
Insulin detemir (Levemir) |
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1st Generation Sulfonylureas
Used for? |
Tolbutamide (Orinase)
Chlorpropamide (Diabinese) Tolazamide (Tolinase) Acetohexamide (Dymelor) Potent Hypoglycemic agents |
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2nd Generation Sulfonylureas
how different? |
Glyburide (Micronase)
Glipizide (Glucotrol) Glucotrol XL* Glimepiride (Amaryl) 100x more potent |
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Meglinitides
-used for |
Repaglinide (Prandin)
Nateglinide (Starlix) Reduce post-prandial glucose |
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Biguanides
-mech? |
Metformin (Glucophage)
decrease hepatic glucose production -warning lactic acidosis |
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Alpha Glucosidase Inhibitors
mech? |
Acarbose (Precose)
Miglitol (Glyset) prevent breakdown carbs, delayed glucose absorption |
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Thiazolidinediones
“glitazones” mech? |
Rosiglitazone (Avandia)
Pioglitazone (Actos) sensitize tissues to insulin, bringing glucose into fat and muscle |
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Incretin Mimetic Agent
mech? |
Exenatide (Byetta)
-looks like glucose, increase glucose dependant insulin secretion and slow gastric emptying |
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Amylin agonist
mech? |
Pramlintide (Symlin)
delay gastric emptying |
