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24 Cards in this Set

  • Front
  • Back
_________ discovered the molecular nature of genes while studying the pneumonia bacteria.
Griffith
What was different about the two stains of bacteria?
The disease-causing bacteria formed smooth colonies while the harmless strain produced rough-edged colonies.
How did Griffith determine that the bacteria did not produce a poison?
He heated the culture and found that it did not kill the mice.
______ is the ability of one strain of bacteria to be changed into another strain of bacteria.
Transformation
What was the tranforming factor in the transformation process?
Genes
What did Avery discover about the heat-killed bacteria (disease-causing strain)?
That the nuclei acid DNA stores and transmits genetic information from one generation to another.
_____________ is a virus that infects bacteria.
Bacteriophage
What is bacteriophage composed of?
DNA or RNA core and a protein coat.
Why did Hershey and Chase use the radioactive isotopes of phosphorus-32 and sulfur-35 to determine what part of the bacteriophagus entered in infected cell?
Because DNA contains no sulfur and protein contains no phosphorus- the isotopes would act as markers.
What was the conclusion of the Hersey/Chase experiment?
That the genetic material of the bacteriophage is DNA.
What are the 3 critical things that genes are known to do:
1
2
3
1. carry info. from one generation to the next
2. determine the heritable characteristics of offspring
3. easily copied
DNA is a long molecule made up of units called _______.
nucleotides
Each nucleotide in DNA is made up of:
1
2
3
1. 5-carbon sugar (deoxyribose)
2. phosphate group
3. nitrogenous base
What are the 4 kinds of nitrogenous bases in DNA?
1
2
3
4
1. adenine
2. guanine
3. cytosine
4. thymine
__________ and ________ belong to the group of compounds known as purines.
Adenine and guanine
___________ and _______ belong to the group of compounds known as pyrimidines.
Cytosine and thymine
How can you distinguish the purines from the pyrimidines in structure?
The purines have two rings and the pyrimidines have one ring.
The backbone of the DNA chain is formed by ____ and _________.
sugar and phosphate groups.
What is Chargaff's Rule?
That guanine = cytosine and adenine = thymine
What is important about the work Franklin did with the x-ray?
1
2
1. the x-shaped pattern suggest the helix shape
2. the shape suggest two strands
_________ and _______ used Franklin's x-rays to do what?
Develop the double helix model of DNA. (two strands wound around each other)
What is the holding the double helix ladder together?
hydrogen bonds form between the nitrogenous bases, providing the attraction
What did the hydrogen bonds explain?
Why there are an equal number of adenine to thymine and guanine to cytosine.
(Chargaff's Rule)
What is this pairing called?
base pairing