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24 Cards in this Set
- Front
- Back
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What are the four (4) types of MS?
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relapsing/remitting MS
primary progressive MS secondary progressive MS progressive-relapsing MS |
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Which type of MS is characterized by clearly defined flare-ups followed by periods of remission?
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relapsing/remitting MS
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Which type of MS is most common (85%)?
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relapsing/remitting MS
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Which type of MS is characterized by gradual decline without periods of remission?
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primary progressive MS
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Which type of MS is characterized by clearly defined flare-ups that eventually becomes continuous deterioration?
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secondary progessive MS
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Which type of MS is characterized as progressive with the addition of sudden episodes of new symptoms or worsened existing ones?
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progressive-relapsing MS
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What are the ABC drugs used in MS?
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A - Avonex (beta interferon-1a)
B - Betaferon (beta interferon-1b) C - Copaxone (GLATiramer) |
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What is the first drug given for initial therapy of MS?
What is the dose? |
Solu-Medrol (methylprednisolone)
1 gram IV daily for 5 days |
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What is the order of the ABC drugs for MS?
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A (Avonex), B (Betaferon), C (Copaxone)
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What are the 7 symptoms of MS?
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spasticity
fatigue bowel/bladder dysfunction depression tremor pain erectile dysfunction |
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What is the prevalence of MS in men compared to women?
What is the average age range of diagnosis? |
females > males
diagnosed ages 16-40 |
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What four (4) amino acids are found in Copaxone?
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GLATiramir
glutamic acid lysine alanine tyrosine |
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What is the pathophysiology of MS?
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demyelination of neurons in the CNS (brain and spinal cord)
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What is the pathophysiology of ALS?
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progressive degeneration of motor neurons in the spinal cord, brainstem, and cerebral cortex (CNS)
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What is the only approved treatment for ALS?
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riluzole (Rilutek)
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Once diagnosed with ALS, the prognosis is death within ___ years
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5
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How is Huntington's disease contracted?
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autosomal dominant genetic disorder
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What are the four (4) treatments (drug classes) for Huntington's disease?
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dopamine receptor antagonists
catecholamine depletors anxiolytics antidepressants |
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Which type of Tourette's syndrome is characterized by involuntary utterances of vulgar or obscene words?
-coprolalia -echolalia -echopraxis |
coprolalia
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Which type of Tourette's syndrome is characterized by involuntary parrott-like repetition of a work or sentence just spoken by another person?
-coprolalia -echolalia -echopraxis |
echolalia
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Which type of Tourette's syndrome is characterized by involuntary imitation of movements made by another person?
-copralalia -echolalia -echopraxis |
echopraxis
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In tardive dyskinesia, which part of the body often moves first?
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tongue
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In tardive dyskinesia, denervation supersensitivity is secondary to what causes? (4)
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drugs (antipsychotics, antihistamines, metoclopramide)
chronic alcohol abuse Alzheimer's cardiovascular disease |
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What are some treatments for tardive dyskinesia? (3)
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remove causal agent
catecholamine-depleting agent (reserpine) neuroleptic change to an atypical agent (clozapine) others - CCBs, anti-serotonin agents (cyproheptadine), TCAs, baclofen, vitamin E |
