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38 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Antidiarrheal Drugs (5)
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1. Bismuth salicylate
2. Loperamide 3. Diphenoxylate 4. Clonidine 5. Alosetron |
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Prokinetics (9)
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1. Bethanechol
2. Cisapride 3. Tegaserod 4. Metoclopramide 5. Domperidone 6. Neostigmine 7. Fiber 8. Saline laxative |
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Anti-Emetics (6)
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1. Ondansetron
2. Metoclopramide 3. Chlorpromazine 4. Scopolamine 5. Promethazine 6. D9-THC |
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Emetics (2)
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1. Ipecac
2. Apomorphine |
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IBD (5)
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1. Sulfalazine
2. Prednisone 3. Azathioprine/6-MP 4. MTX 5. Infliximab |
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Acid (5)
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1. Tums/NaHCO3-/Al(OH)3/Mg(OH)2
2. Cimetidine 3. Ranitidine 4. Omeprazole 5. Pirenzipine |
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Mucosal Protection (3)
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1. Sucralfate
2. Misoprostol 3. Bismuth salicylate |
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H. Pylori (2)
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1. Clarithromycin + Omeprazole + Amoxicillin/Metronidazole
2. Tetracycline + Omeprazole + Metronidazole + Bismuth |
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What receptors activate the CTZ?
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5-HT3, NK1, D2
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What receptors activate the Cerebellum in vomiting?
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H1, M1
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What receptors activate the NTS?
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H1, M1, 5-HT3, NK1
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Antidiarrheal - Traveler's Diarrhea
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Bismuth
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Salicylate
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Antidiarrheal - SE: Toxic megacolon
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Loperamide
Diphenoxylate (w/ atropine) |
mu agonists
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Antidiarrheal -
Heroin withdrawal Diabetic neuropathy (Sy) |
Clonidine
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a2 agonist
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Antidiarrheal - SE: Ischemic colitis
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Alosetron (5-HT3 ANTagonist)
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IBS-D
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Prokinetic: Post-op
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1. Metoclopramide (SE: EPS)
(2a. Domperidone) 2b. Bethanachol (SE: Muscarinic) |
D2 antag
D2 antag M agonist |
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Prokinetic: IBS-C in women
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Cisapride
Tegaserod |
5-HT-R Agonist
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Prokinetic: "Acute large distention"
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Neostigmine
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Butt ipecac
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Prokinetic: Fiber ->
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Large, voluminous, hard stools
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Prokinetics: severity?
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1. Aluminum... (Aluminimum)
2. Mg... (Makes go) |
Osmotic agents
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Anti-emetic: 5-HT3 antag SE?
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P450
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Ondansetron
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Anti-emetic: D2 antagonist/5-HT4 agonist
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Metoclopramide
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Anti-Emetic: D2 antagonist
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Chlorpromazine
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Anti-emetic w/ muscarinic SE's
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Scopolamine (transdermal)
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Anti-Emetic: SE = drowsiness
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Promethazine
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H1 antagonist (@ NTS + Cerebellum)
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Anti-Emetic: CB-1 agonist?
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Dronabinol / D9-THC
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Emetics: Plant (SE's)
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E-lyte disturbance...
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Ipecac
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Emetics: Apomorphine receptor?
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D2/D1 agonist
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IBD: first line?
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Sulfalazine
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COX-I / NSAID
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IBD: Glucocorticoid
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Prednisone
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IBD: Purine analogs?
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1. Azathioprine>6-MP
2. MTX |
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IBD: chimeric immunoglobulin?
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Infliximab
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Acid: SE's of weak bases?
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Tums: Hypercalcemia
NaHCO3-: Systemic alkalosis (ALKa-seltzer) Al(OH)3/Mg(OH)2: dual effects |
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Acid: H2 antagonists
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Cimetidine
Ranitidine |
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Acid: SE's of cimetidine?
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Inhibits DHT binding androgen receptors > gynecomastia etc
Impaired renal clearance and inc creatinine Monitor P450 (excreted metab/unmetab) |
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Acid: Pirenzipine?
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M1-selective ANTAGonist
Blocks pathway: DMNV>NTS>ENS>Parietal |
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Acid: Omeprazole - Mech?
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Goes through stomach to duod, abs d.t. higher pH, goes through blood to Gastric parietal cell, activates outside cell to bind/"silence" pump
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Acid: Omeprazole: SE's
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1. Hypomagnesia
2. Osteomalacia (dec Ca2+ abs) 3. Hypergastrinemia 4. B12 malabsorption (dt dec IF) |
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