Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
12 Cards in this Set
- Front
- Back
|
protein used to transport iron
|
transferrin
|
|
|
the form in which iron is stored in macrophages of reticuloendothelail system
|
ferritin or hemosiderin
|
|
|
mechanism of iron absorption
|
absorbed in the duodenum, delivered to marrow by transferrin and stored as ferritin or hemosiderin in macrophages of the reticuloendothelial system
|
|
|
used in iron-deficient anemia patients with malabsorbtion syndromes or pts intolerant to oral iron preparations. Reticuloendothelial cells phagocytize the preparation splitting the iron from the drug.
|
iron dextran (parenteral iron formulation)
|
|
|
used in iron-deficiency pts w/ malabsorption syndroomes or pts intolerant to oral preparations. exchange mechanisms transfer the iron to transferrin. Approved for iron deficiency anemia in chronic hemodialysis pts who are recieving suuplemental EPO therepy.
|
iron sucrose (venofer)---parenteral iron form
|
|
|
used in chronic renal disease in pts w/ iron-deficiency anemia
|
Ferrlecit (parenteral iron form)
|
|
|
`In iron deficiency pts with malabsorption syndromes or pts intolerant to oral iron preparations this is given containing 50 mg/ml iron parenterally by multiple slow injections to correct the deficiency.
|
ferric hydroxide and dextran
|
|
|
treatment of iron toxicity (presents w/ bloody vomiting, diarrhea, massive fluid and blood loss into GI tract)
|
proper ventilation and administration of deferoxamine, a chelating agent that chelates iron and excreted renally w/ orange or pink-red urine (deferoxamine-iron complex). Stop therapy when the color of the urine turns normal
|
|
|
mechanism of B12 absorption
|
parietal cell intrinsic factor in the distal ileum complexes w/ B12 for absorption (intrinsic factro-dependant route) and B12 is absobed in the stomach (intrinsic factor indepandant route)
|
|
|
A decrease in the production of intrisic factor results in (acquired/congential) pernicious anemia while dysfunction of the intrinsic factor causes (aquired/congential) pernicious anemia
|
decrease in producton=acquired
dysfunction=congenital |
|
|
transport protein of B12
|
transcoalamin II
|
|
|
treatment of megaloblastic anemia
|
combo of folate and cyanocobalamin
|
