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40 Cards in this Set

  • Front
  • Back
What receptors does epinephrine activate?
Alpha 1 & 2
Beta 1 & 2
What receptors does norepinephrine activate?
Alpha 1 & 2
Beta 1
What receptors does Dopamine activate?
Alpha 1
Beta 1
How is acetylcholine removed from the synapse?
Through the actions of acetylcholinesterase (AChE)
How is norepinephrine removed from the synapse?
Inactivation by MAO
What are the categories of cholinergic drugs?
Muscarinic Agonist and Antagonist
Ganglionic Agonist and Antagonist
Neuromuscular Antagonist
Cholinesterase Inhibitors
What is the prototype of a muscarinic agonist?
Bethanechol is a _____.
Muscarinic agonist
What is the prototype of a muscarinic antagonist?
Atropine is a _____.
Muscarinic Antagonist (Anticholinergic drug)
What is typically prescribed for OAB (over reactive bladder)?
Anticholinergic Drug (Muscarinic Antagonist)
What is the specific drug for OAB?
Oxybutynin (Muscarinic Antagonist)
What does the M1 receptor mediate?
Salivation of the Salivary Glands
What does the M2 receptor mediate?
Slowing of the Heart Rate
What does the M3 receptor mediate?
Salivation of the Salivary Glands
Bladder and Bowel Movement
What are the uses for a muscarnic agonist?
Urinary Retention
What are the uses for a muscarnic antagonist?
Preanethetic Medication (Decrease Salivations)
Hypermotility of the bowel and bladder
Muscarnic Agonist Posioning
What are the adverse effects of Bethanechol?
Exacerbation of Asthma
What are the Adverse effects of Atropine?
Dry Mouth
Bowel and Bladder retention
What is the treatment of Atropine poisioning?
Physostimine, AChE inhibitor
What are drug interactions of atropine?
What is the prototype of Cholinesterase Inhibitor?
Neostigmine is a _____.
Cholinesterase Inhibitor
Cholinesterase Inhibitors act like muscarnic _____.
What is the use of Neostigmine?
Treatment of Myasthenia Gravis
What are the Adverse effects of a cholinesterase inhibitor?
Excessive Muscarnic Activation
Neuromuscular Blockade
What is Physostigmine?
Cholinesterase Inhibitor
What is the use of Physostigmine?
Treatment of Muscarnic Antagonist
What is Echothiophate?
Irreversible cholinesterase inhibitor; Used for glaucoma
What is a cholinergic crisis?
Overdose of a cholinesterase inhibitor
Excessive Muscarinic Activity
What is a Myasthenic Crisis?
Condition of Myasthenia Gravis
Not enough acetylcholine
What is used to treat a Cholinergic Crisis?
A muscarinic antagonist
What is the prototype of a Neuromuscular Antagonist (Blocking Agent)?
Turbocurarine is a ________.
Neuromuscular Blocking Agent
What are the uses of Turbocurarine?
Used for muscle relaxation during invasive procedures
What are the Adverse Effects of Turbocurarine?
Respiratory Arrest
Hypotension (Release of Histamine)
What is Succinylcholine?
Depolarizing Neuromuscular Blocker
What is the prototype for a depolarizing neuromuscular blocker?
What are the uses of Succinylcholine?
Short-term muscle relaxation
What are the Adverse Effects of Succinylcholine?
Postoperative pain (due to seizure before becoming effective)