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40 Cards in this Set
- Front
- Back
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What receptors does epinephrine activate?
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Alpha 1 & 2
Beta 1 & 2 |
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What receptors does norepinephrine activate?
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Alpha 1 & 2
Beta 1 |
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What receptors does Dopamine activate?
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Dopamine
Alpha 1 Beta 1 |
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How is acetylcholine removed from the synapse?
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Through the actions of acetylcholinesterase (AChE)
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How is norepinephrine removed from the synapse?
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Reuptake
Inactivation by MAO |
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What are the categories of cholinergic drugs?
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Muscarinic Agonist and Antagonist
Ganglionic Agonist and Antagonist Neuromuscular Antagonist Cholinesterase Inhibitors |
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What is the prototype of a muscarinic agonist?
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Bethanechol
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Bethanechol is a _____.
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Muscarinic agonist
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What is the prototype of a muscarinic antagonist?
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Atropine
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Atropine is a _____.
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Muscarinic Antagonist (Anticholinergic drug)
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What is typically prescribed for OAB (over reactive bladder)?
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Anticholinergic Drug (Muscarinic Antagonist)
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What is the specific drug for OAB?
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Oxybutynin (Muscarinic Antagonist)
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What does the M1 receptor mediate?
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Salivation of the Salivary Glands
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What does the M2 receptor mediate?
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Slowing of the Heart Rate
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What does the M3 receptor mediate?
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Salivation of the Salivary Glands
Bladder and Bowel Movement Eye |
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What are the uses for a muscarnic agonist?
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Urinary Retention
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What are the uses for a muscarnic antagonist?
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Preanethetic Medication (Decrease Salivations)
Bradycardia Hypermotility of the bowel and bladder Muscarnic Agonist Posioning |
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What are the adverse effects of Bethanechol?
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Bradycardia
Incontinence Exacerbation of Asthma |
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What are the Adverse effects of Atropine?
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Dry Mouth
Photophobia Tachycardia Bowel and Bladder retention Anihydrosis |
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What is the treatment of Atropine poisioning?
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Physostimine, AChE inhibitor
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What are drug interactions of atropine?
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Antidepressants
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What is the prototype of Cholinesterase Inhibitor?
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Neostigmine
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Neostigmine is a _____.
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Cholinesterase Inhibitor
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Cholinesterase Inhibitors act like muscarnic _____.
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Agonist
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What is the use of Neostigmine?
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Treatment of Myasthenia Gravis
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What are the Adverse effects of a cholinesterase inhibitor?
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Excessive Muscarnic Activation
Neuromuscular Blockade |
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What is Physostigmine?
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Cholinesterase Inhibitor
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What is the use of Physostigmine?
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Treatment of Muscarnic Antagonist
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What is Echothiophate?
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Irreversible cholinesterase inhibitor; Used for glaucoma
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What is a cholinergic crisis?
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Overdose of a cholinesterase inhibitor
Excessive Muscarinic Activity |
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What is a Myasthenic Crisis?
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Condition of Myasthenia Gravis
Not enough acetylcholine |
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What is used to treat a Cholinergic Crisis?
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A muscarinic antagonist
Atropine |
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What is the prototype of a Neuromuscular Antagonist (Blocking Agent)?
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Turbocurarine
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Turbocurarine is a ________.
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Neuromuscular Blocking Agent
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What are the uses of Turbocurarine?
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Used for muscle relaxation during invasive procedures
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What are the Adverse Effects of Turbocurarine?
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Respiratory Arrest
Hypotension (Release of Histamine) |
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What is Succinylcholine?
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Depolarizing Neuromuscular Blocker
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What is the prototype for a depolarizing neuromuscular blocker?
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Succinylcholine
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What are the uses of Succinylcholine?
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Short-term muscle relaxation
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What are the Adverse Effects of Succinylcholine?
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Postoperative pain (due to seizure before becoming effective)
Hyperkalemia |
