Drugs Of Choice In Bacterial Id

Front 1

M. avium-intracellulare

Back 1

Clarithromycin or Azithromycing (due to superb intracellular killing!)

Front 2

Prostatitis

Back 2

TMX/SMX or Fluroquinolones (due to excellent penetrance into inflammed prostate)

Front 3

Vibrio cholera

Back 3

Doxycycline and fluids

Front 4

H. pylori

Back 4

4 drug regeime: Tetracycline, Metronidazole, Bismuth salt, H+ pump inhibitor

Front 5

RIckettsia

Back 5

Doxycycline

Front 6

Group A strep pyrogenes pharyngitis

Back 6

Pen G for 10 days or one Benzathine IM shot

Front 7

All stages of syphylis

Back 7

Pen G

Front 8

Legionella

Back 8

Azithromycin (a macrolide)

Front 9

Penicillinase-Producing Staph aureus (once MRSA has been eliminated)

Back 9

Naficillin

Front 10

Enterococcus

Back 10

Ampicillin w/ synergistic killing via aminoglycoside

Front 11

Listeria

Back 11

Amoxicillin (PO aminopenicillin)

Front 12

Serious UTI's

Back 12

Ampicillin/Gentamycin combo (amp hits the GM+ enterococci and Gent hits the GM- enterics)

Front 13

C. jejuni

Back 13

Azitrhromycin or Fluroquinolone

Front 14

Sheigella

Back 14

Azithromycin

Front 15

Traveller's Diarrhea (ETEC)

Back 15

Fluroquinolone

Front 16

What 2 pathogens are resistant to all cephalosporins?

Back 16

MRSA and Enterococcus

Front 17

Prophylaxis for surgery at all sites except the bowel or appendix

Back 17

Cephalexin, Cefazolin (1st Gen cephalosporins)

Front 18

Prophylaxis for colon or appendix surgery

Back 18

Cefoxitin (2nd gen cephalosporin)

Front 19

Mixed aerobe/anaerobe infection

Back 19

Cefoxitine (2nd gen cephalosporin)

Front 20

CA-acquired pneumonia

Back 20

. Cefuroxime or Cefaclor (2nd gen cephalosporin)

. TRI and FIX (3rd gen - TAZ)

Front 21

Generations of Cephalosporins effective against Pseudomonas

Back 21

3rd and 4th

Front 22

Generations of Cephalosporins able to penetrate the CSF?

Back 22

3rd and 4th

Front 23

Antibiotics that can cover Pseudomonas aeruginosa (x8)

Back 23

. Pipercillin and Ticarcillin (and their B-lacatamase combo forms)

. Ceftazidime (3rd gen)

. Cefepime (4th gen)

. All Carbapens - Erta (ie. Imi, Mero, Dori)

. Aztrenom (monobactam)

. Ciprofloxacin (quinolone)

. Aminoglycosides

. Colistin (poymixin E)

Front 24

Antibiotics that cover anaerobes (including B. fragilis) (x6)

Back 24

. Metronidazole

. Clindamycin

. All penicillin/B-lactamase inhibitor combos

. Cefoxtin (2nd gen ceph)

. Tigecycline

. Carbapenems (Imi, Dori, Mero, Erta)

Front 25

Antibiotics that cover Vanco-resistant Enterococci (VRE) x3

Back 25

Tedi-/Linezolid

*Daptomycin* - DOC

Tigecycline

Front 26

Antibiotics that covers MRSA and MRSE (x5)

Back 26

. Vanco

. Telva-/Dalbavancin

. Tedi-/Linezolid

. Daptomycin

. Quinpristen/dalfopristin

. Tigecycline

. TARO (5th gen cephalosporin)

Front 27

Uncomplicated UTI/Cystitis

Back 27

TMP/SMX or Fluroquinolone

Front 28

Gram + Cocci Uncomplicated pyelonephritis

Back 28

Ampicillin or Vanco

Front 29

Gram - Rod Uncomplicated Pyelonephritis

Back 29

. 3rd Gen Ceph (TRI, FIX, TAZ)

. Gent

. Aztreonam

Front 30

Single oral dose for Gonorrhea

Back 30

CeFIXime (3rd gen)

Front 31

Best empirical therapy for Bacterial Meningitis

Back 31

CeTRIaxone (3rd gen)

Front 32

Empiric trx for Human Bite Wound

Back 32

Amoxicillin/Sulbactam (Unasyn)

Front 33

Nonsocomial Aerobic GM(-) Infection in a pt. w/ a penicillin allergy

Back 33

Aztreonam

Front 34

Empiric trx of Febrile Neutropenia

Back 34

All carabapenems except Erta (Imi, Dori,Mero)

Front 35

Enterococcal Endocarditits

Back 35

Aminoglycoside + Penicillin (mainly Amp or Piper)

Front 36

Aceinobacter baumanni (Iraq war veterans bacteria)

Back 36

Colistin (polymixin E)

Front 37

Mechanisms of Vancomycin resistance

Back 37

*NOT x-resistant w/ B-lactams*

. VRE = vanA & B genes change precursor to D-ala-D-lactate

. VISA = thicker cell wall

. VRSA = vanA gene transferred from eneterococcus to staph

Front 38

C. difficle

Back 38

Oral Vanco

Fidaxomycin

Metronidazole

Front 39

Bordetella pertusis

Back 39

Azithromycin

Front 40

Yersinia pestis

Back 40

Tetracycline

Streptomycin (aminoglyc)

Front 41

Brucella

Back 41

Doxy + Gent (or Rifamp can sub for gent)

Front 42

H influenzae

Back 42

2nd (FAC,FOX,FUR) & 3rd gen Ceph (TRI,FIX,TAZ)

Fluroquinolone (Cipro, Levo, Moxi)

Augmentin/Clav.

Front 43

Tularemia

Back 43

Aminoglycosides

Front 44

Diptheria

Back 44

Antitoxin + Pen or Erythro

Front 45

Anthrax

Back 45

Doxy and Cipro

Front 46

Tetnus

Back 46

Antitoxin + Pen G + TDAP booster

Front 47

Botulism

Back 47

If adult food-bourne -> antitoxin

If infant from honey -> none, self-limiting

Front 48

Enterobacter/E. coli

Back 48

CAT: Cephalosporin + Aminoglyc. + TMP-SMX

Front 49

Hansen's Disease (Mycobacterium leprae)

Back 49

Dapson w/ either Rifamp or clofazomine