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13 Cards in this Set
- Front
- Back
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Opiate mechanism of action
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Acts on the mu receptor of presynaptic GABA neurons
Inhibit GABA neurons causing more DA to be released |
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Buprenorphine
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Mu-agonist for opiate detoxification
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Naloxon
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Blocks the euphoric effects of opiates
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Clonidine
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Controls withdrawal symptoms of opiates
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Cannabinoids mechanism of action
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Act on CB1 receptors of presynaptic GABA neurons
Increase in DA by inhibition of GABA |
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Uses of Cannabinoids
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Anti-emetic
Anti-wasting (cachexia) Decrease in intraocular pressure |
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Psychedelics
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Tryptamines
Phenethylamines |
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Psychedelics mechanism
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Act on 5-HT2A receptors on glutamateric neurons
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Ecstasy mechanism
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Depletes vesicular 5-HT in the CNS
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Gammahydroxybutyric acid
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Low dose = increased sociability
High dose = date rape |
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Types of Hallucinogens
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PCP
Ketamine |
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Acute actions of Hallucinogens
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Low dose = stimulant
Moderate dose = hallucinogenic Also used as anesthetic |
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Chronic action of Hallucinogens
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Dependence and addiction
Users are violent |
