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21 Cards in this Set
- Front
- Back
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What are the 6 categories for self-administered, non-medical drugs?
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Opiods
CNS depressants CNS stimulants Hallucinogens Inhalants Steroids |
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Substance dependence
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a pattern of compulsive drug use: overwhelming involvement w/ getting & using drugs w/ high likelihood of relapse
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Psychological dependence
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a strong desire to achieve pleasure, avoid dysphoria, & continue drug use; in absence of physical dependence, psychological dependence sustains drug-seeking behavior. Occurs w/ all drugs of abuse
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Kinetic (pharmacokinetic) Tolerance
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Changes in distribution or metabolism of a drug w/ repeated uses such that plasma levels are reduced relative to the first dose
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Cellular tolerance
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adaptation to a drug at the cellular level; downregulation of receptors
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Physical dependence
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state that develops from re-setting homeostatic mechanisms in response to repeated drug use. This is a Nl response to clinical Tx for many drugs
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Cross-dependence
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one drug of a class can substitute for another to prevent abstinence; methadone & heroin
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Opioids (6)
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Heroin
Morphine Methadone Meperidine Codeine Buprenorphine |
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CNS depressants (2)
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Alcohol
Benzodiazepines |
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CNS stimulants (4)
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Methamphetamine
Cocaine Nicotine Methylphenidate |
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Opioid antagonist
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Naltrexone
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Hallucinogens (4)
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Isyergic acid diethylamide (LSD)
Phencylidine (PCP) Tetrahydrocannabinol (THC) MDMA (Ecstacy) |
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Inhalant
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Toulene
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Sx of Opioid OD
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respiratory depression, pulmonary edema, & CV collapse
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Tx for Opioid OD
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Naloxone
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Detoxification of Opioid abuse
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Naloxone
Psychiatric & social counseling |
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Sx of CNS depressant OD
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Loss of inhibitions, sluggishness, difficulty thinking, memory impairment, & slower speech
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Tx of CNS depressant OD
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Supportive
*Flumazenil for benzodiazepine |
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Abstinence syndrome in CNS depressants
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CNS excitation leading to SZ, exhaustion, & CV collapse
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Sx of CNS stimulant OD
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Excited, restless, irritable, insomiac, rapid speech, confusion, paranoia
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Sx of Hallucinogen OD
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Alteration of sensation, hallucinations, euphoria, +/- tachycardia & HTN
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