Drugs In The Cns

Front 1

What class of drugs are Tricyclics and how do they work?

Back 1

Antidepressant
Act primarily as serotonin-norepinephrine reuptake inhibitors (by blocking the serotin transporter SERT and norephinephine transporter NET) leading to higher levels of these neurotransmitters.

Front 2

What class of drugs are Selective Serotonin Reuptake Inhibitors SSRIs and how do they work?

Back 2

Antidepressant
Increase the extracellular level of serotonin by inhibiting its reuptake into the presynaptic cell.

Front 3

What class of drugs are MAO inhbitors and how do they work?

Back 3

Antidepressant
Inhibit monoamine oxidase which breaks down serotonin, melatonin, dopamine, adrenaline and noradrenaline increasing their availability.

Front 4

What class of drugs are Serotonin-Noradrenaline reuptake inhibitors and how do they work?

Back 4

Antidepressant
Increase the extracellular concentration of serotonin and norepinephrine.

Front 5

What type of drug is Lithium and how does it work?

Back 5

Antidepressant
Works as a mood-stabilizing agent

Front 6

What type of drug are Benzodiazepines and how do they work?

Back 6

Anxiolytic
Act be enhancing the effect of GABA to decrease the excitability of neurons by binding the GABA-A receptor.

Front 7

What type of drugs are Barbiturates and how do they work?

Back 7

Anxiolytic
bind to GABA-A receptor and potentiates the effect of GABA

Front 8

What type of drugs are 5HT1 receptor agonists eg Buspirone?

Back 8

Anxiolytic

Front 9

What are the major targets of anti-epileptic drugs/anticonvulsants?

Back 9

Voltage gated sodium channels and enhancement of components of the GABA system

Front 10

Name three anti-epileptic/anticonvulsant drugs?

Back 10

Barbiturates eg diazepam, Carbamazepine, Phenytoin

Front 11

Name four types of drugs that can be used against anxiety?

Back 11

Benzodiazepines
Barbiturates
5HT1 receptor agonists
Beta blockers (for somatic symptoms)

Front 12

Name five types of drugs that can be used as antidepressants?

Back 12

Tricyclics, SSRIs, MAO inhibitors, Serotonin-noradrenaline reuptake inhibitors, Lithium