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43 Cards in this Set
- Front
- Back
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What drives the RA process?
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Activated T-cells
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What type of drug is Methotrexate?
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NonBio DMARD
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What type of drug is Hydrozychloroquine?
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NonBio DMARD
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What type of drug is Sulfasalazine?
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NonBio DMARD
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What type of drug is Gold?
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NonBio DMARD
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What type of drug is Azathioprine?
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NonBio DMARD
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What type of drug is Cyclosporine?
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NonBio DMARD
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What type of drug is Penicillamine?
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NonBio DMARD
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What drug works as an anti-folate?
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Methotrexate
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What enzyme does methotrexate block?
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Dihydrofolate reductase
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What drug prevents conversion of uridine to thymidine?
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Methotrexate
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What drug prevents the acidification of macrophage cytosol?
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Hydroxychloroquine
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What drug inhibits pyrimidine synthesis?
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Leflunamide
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What drug blocks ororate pathway?
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Leflunamide
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What type of cells does Leflunamide primarily effect?
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T-cells
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What drug is metabolized in the colon to activate substances?
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Sulfasalazine
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What drug suppresses phagocytosis by macrophages?
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Gold
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What type of cell can Gold also suppress?
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T-cells
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What drug is a purine analog used to block DNA synthesis and primary action seems to be on the T-cell?
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Azathioprine
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What drug is an immunosuppressant used to control transplant rejection?
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Cyclosporine
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What drug is an inhibtor of calcineurin?
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Cyclosporine
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What drug uses copper as a binding agent?
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Penicllamine
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What drug suppresses T-cells and macrophage function?
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Penicillamine
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What type of drug is Etanercept?
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Bio (Enbrel)
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What type of drug is Leflunamide?
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NonBio DMARD
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What type of drug is Inflixumab?
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Bio DMARD
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What type of drug is Anakinra?
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Bio DMARD
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What type of drug is Rituxumab?
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Bio DMARD
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What type of drug is Abatacept?
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Bio DMARD
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Etanercept and Inflixumab inhibit what?
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TNF
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Anakinra is an antagonist of what?
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Interleukin 1 Receptor
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Rituxumab is an inhibitor of what?
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CD20 (Binds to CD20 on B Cell)
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Abatacept binds to what on the T-cell to prevent its activation?
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CD86
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What type of drug is Allopurinol?
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Reduces uric acid for Gout
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What drug blocks formation of uric acid by inhibiting xanthine oxidase?
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Allopurinol
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What type of drug is Probenicid?
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Increases excretion of uric acid
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What type of drug is Sulfinpyrazone?
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Increases excretion of uric acid
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What type of drug is Colchicine?
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Microtubule inhibitor of gout
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Inhibits COX & scavenges free radicals?
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Sulfsalazine
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What inhibits T cell activation?
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Cycolosporine
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What drug blocks TNF alpha?
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Entanercept
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What increases uric acid excretion in Gout?
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Probenicid
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What inhibits uric acid synthesis?
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Allopurinol
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