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10 Cards in this Set
- Front
- Back
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What is the most important bacteria for duodenal ulcers?
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H pylori infection
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Some anti-secretion drugs for peptic ulcers?
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H2 receptor antagonist
Protein pump inhibitors anti-muscarinic gastrin antagonist somatostatin analogues |
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some examples of mucosal protection drugs?
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Sucralfate
prostaglandin analogues bismuth antacids |
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Ends of names of H2 receptor and protein pump inhibitor?
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H2: tidine
pp: prazole |
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which one is reversible?
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H2 is reversible (inhibits acid secretion induced by histamine, gastrin, Ach --> kinda on enteroendocrine cells)
PPI is irreversible (inactivates H+/K+ pump at parietal cell) |
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Which cannot be administered with warfarin?
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cimetidine
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which drug is specific in pH? which one is administered with NSAIDs? choose from prostaglandins and sucralfate and bismuth
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sucralfate and bismuth adhere to ulcer at acidic pH (so DO NOT take with antacids)
prostaglandin analogues is used with NSAIDs, and DO NOT use in pregnancy |
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which drug inhibits pepsin by neutralising pH?
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Antacids. It is a weak base. Pepsin is only converted from pepsinogen at acidic pH
better for duodenal ulcers than gastric ulcers may become insoluble complexes with other drugs |
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what does combination of bismuth and amoxicillin do?
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destroy cell wall of H pylori
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what medications can cause GERD?
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anti-cholinergics, nitrates, Calcium channel blockers, dopamine agonists
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