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46 Cards in this Set
- Front
- Back
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Name all the penicillins
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Pen G
Pen V Amoxicillin Ampicillin Ticarcillin Nafcillin |
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Name all the beta lactamase inhibitors
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Clavulanic acid
Sulbactam Tazobactam |
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Name all aminoglycosides
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Streptomycin
Neomycin Gentamycin Tobramycin |
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3 side effects of aminoglycosides?
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Nephrotoxic
Neuromuscular blockade Ototoxic |
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Chloramphenicol mechanism?
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Binds to 50S ribosome and inhibits transpeptidation
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Diseases that you use Quinolones for?
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UP SSHE GCD
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Name all the Quinolones?
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Cipro
Norflo Oflo |
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Vancomycin diseases?
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Only G+
staph meningitis MRSA C diff suprainfection |
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Name all the macrolides?
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Erythromycin
Azithromycin Clarithromycin |
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Erythromycin mechanism?
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Binds 50S ribosome, inhibits aminoacyl translocation
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What causes red man syndrome?
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vancomycin
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mechanism of quinolones
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inhibits DNA gyrase
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List all NRTIs
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Zidovudine (AZT)
Zalcitabine Lamivudine Didanosine |
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Abbreviations for:
Zidovudine Zalcitabine Lamivudine Didanosine |
Zidovudine AZT
Zalcitabine ddC Lamivudine 3TC Didanosine ddI |
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Two chain terminator AIDS drugs?
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Lamivudine
Didanosine |
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Zidovudine (AZT):
Clinical Uses Acronym? |
POWDA TT
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Zidovudine (AZT):
Side Effects acronym? |
FLANGS
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Zalcitabine
Side Effects acronym? |
MM NN EHG
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When is didanosine indicated?
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When AZT therapy has proven successful (ddI works longer before resistance kicks in)
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Didanosine
Side Effects acronym? |
NB PH LGS
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The only NtRTI is?
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Tenofovir
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The NNRTIs are?
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Nevirapine
Delavirdine Efavirenz |
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AIDS Protease Inhibitors are?
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Indinavir
Nelfinavir Rotinavir Saquinavir |
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Herpes Simplex Drugs?
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Acyclovir
Valcyclovir Vidarabine Iduroxine |
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CMV Drugs?
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Gancyclovir
Foscarnet |
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Lassa Fever drug?
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Ribavirin
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Hep B and C drug?
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interferon alpha 2b
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Influenza drug?
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Oseltamivir
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Antifungal Drugs?
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all the -azoles
Ampho B Griso Nystatin Flucytosine |
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Leprosy drugs?
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Dapsone
Rifampin (works for TB too) Clofazimine |
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TB drugs?
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Isoniazid
Rifampin Ethambutol Pyrazinamide Streptomycin (an AMG) |
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Malaria drugs?
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Doxycycline
Chloroquine Mefloquine Primaquine Pyrimeth Pyrimeth-Sulfa Quinine |
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African Trypanosome drugs (gambia and rhodesia)
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Melarsopol
Pentamidine Suramin Nifurtimox Benz |
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2 Pen G mechanisms?
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inhibit transpeptidation and activates autolytic enzyme
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Side effects of Pen G if given IV
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Procaine syndrome
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What are the only penicillins that aren't acid stable?
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Pen G and Nafcillin
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What two things combine to make augmentin?
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clavulanic acid and amoxicillin
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What keeps penems from degrading quickly in vivo?
How? |
cilastatin
it inhibits the renal dihydropeptidase |
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tetracycline diseases acronym?
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CR PP LV MM
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Aminoglycosides contraindication?
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Myasthenia Gravis
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3 drugs that cause hemolytic anemia for patients who are G6PD deficient?
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Chloramphenicol
Primaquine Sulfamethoxazole |
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Metronidazole mechanism?
Cidal or static? |
inhibits DNA synthesis
Cidal |
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Zidovudine mechanism?
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thymidine analogue
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AIDS drug combos, what are all three in order?
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1. 2 NRTIs & 1 Protease Inhibitor
2. 2 NRTIs & 1 NNRTI 3. 1 NRTI & 1 NNRTI & 1 Protease Inhibitor |
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The two characteristics to know about NNRTI (as opposed to NRTI)?
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NNRTI don't need phosph. to be activated
They bind to lipophilic pocket (not substrate binding site) |
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Mechanisms of :
Gancyclovir Foscarnet |
G: GTP analogue
F: Pyrophosphatea analogue which inhibits viral DNA polymerase |
