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63 Cards in this Set

  • Front
  • Back
Lispro
Rapid acting
inject within 15 minutes of meals
Lispro: Onset, Peak and Duration
15 minutes
60-90 minutes
3-4 hrs
Aspart
rapid acting
inject within 15 minutes of meal
Aspart: Onset, Peak and Duration
15 minutes
60-90 minutes
3-4 hours
Glulisine
rapid acting should be injected within 15 minutes of meals
Glulisine
15 minutes
60-90 minutes
3-4 hours
Regular Insulin
short-acting insulin

clear in color
Regular Insulin: Onset, Peak and Duration
30 min-1 hr
2-3 hrs
3-6 hrs
NPH
intermediate-acting insulin

cloudy in color
NPH: Onset, Peak and Duration
2-4 hours
4-10 hours
10-16 hours
Lente
Intermediate-acting insulin
cloudy in color
Lente: Onset, Peak and Duration
2-4 hrs
4-10 hrs
10-16 hrs
Glargine
Long-acting Insulin

DO NOT GIVE IV OR MIX WITH OTHER INSULINS
Glargine: Onset, Peak and Duration
1-2 hrs
no peak
24+ hrs
Detemir
Long-acting Insuline

DO NOT GIVE IV OR MIX WITH OTHER INSULINS
Detemir
1-2 hrs
no peak
24+hrs
NPH/regular 70/30
Humulin 70/30, Novolin 70/30, ReliOn 70/30
NPH/regular 50/50
Humulin 50/50
lispro protamine/lispro 75/25
Humalog 75/25
aspart protamine/aspart 70/30
Novolog Mix 70/30
Sulfonylureas
-Stimulate release of insulin from the pancreas
-Decrease glycogenolysis
-enhance cellular sensitivity to insulin
Side effects of Sulfonylureas
weight gain

hypoglycemia
Sulfonylureas are known as the
"ides"
Glipizide (Glucotrol, Glucotrol XL)
Sulfonylureas
Glyburide (Micronase, DiaBeta, Glynase)
Sulfonylurea
Glimepiride (Amaryl)
Sullfonylurea
Meglitinides
Stimulates a rapid and short-lived release of insulin from the pancreas
side effects of Meglitinides
weight gain and hypoglycemia
Repaglinide (Prandin)
Meglitinide
Nateglinide (Starlix)
Meglitinide
Decrease the rate of hepatic glucose production; augments glucose uptake by tissues, especially muscles
Biguanide
Side effects of Biguanide
Diarrhea, lactic acidosis
Hold Biguanide (metformin).....
48 hours after administration of IV contrast
Metformin (glucophage, Glucophage XR, Riomet, Fortamet)
Biguanide
delays the absorption of glucose from the GI tract
Alpha-Glucosidase Inhibitors
Side effects of Alpha-Glucosidase Inhibitors
gas, abdominal pain, diarrhea
Acarbose (precose)
Alpha-Glucosidase Inhibitors
Miglitol (Glyset)
Alpha-Glucosidase Inhibitors
increases glucose uptake in muscles
decreases endogenous glucose production
Thiazolidinediones
side effects of Thiazolidinediones
weight gain, edema, not for patients with heart failure
Pioglitazone (Actos)
Thiazolidinediones
Rosiglitazone (Avandia)
Thiazolidinediones
Dipeptidyl Peptidase-4 Inhibitors
enhances the incretin system, stimulates release of insulin from pancreatic B cells
decreases hepatic glucose production
side effects of Dipeptidyl Peptidase-4 Inhibitors
URI, sore throat, headache, diarrhea
Sitagliptin (Januvia)
Dipeptidyl Peptidase-4 Inhibitors
Vildaglipton (Galvus)
Dipeptidyl Peptidase-4 Inhibitors
Incretin mimetic
stimulates release of insulin, decreases glucagon secretion, increase satiety, decreases gastric empyting
side effects of Incretin mimetic
n&V, hypoglycemia, diarrhea, headache
Exenatide (Byetta)
Incretin Mimetic
decrease gastric emptying, decrease glucagon secretion, decreases endogenous glucose output from liver, increase satiety
Amylin Analog
Side effect of Amylin Analog
Hypoglycemia, N&V, decreased appetite and headache
Amylin Analog is given
subQ in thigh or abdomen only!
Incretin Mimetic is given
subQ
Glucovance
combo of Metformin & Glyburide
Avandamet
combo Rosiglitazone & Metformin
Metaglip
combo Metformin & Glipizide
Duetact
combo Pioglitazone and Glimepiride
Side effects of combo therapy
Nausea, diarrhea, abdominal pain, lactic acidosis, weight gain, hypoglycemia
What drug is given to prediabetics to prevent diabetes
Biguanide (metformin)
This class of drug is the treatment of choice in Type 2 diabetes
sulfonylureas
Meglitinides are more rapidly absorbed and eliminated therefore you should take it
30 minutes before meals
this class of drugs is also known as "starch blockers"
alpha glucosidase inhibitors
Alpha glucosidase inhibitors are taken
with first bite of food