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6 Cards in this Set
- Front
- Back
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What is Asthma, and it's characteristic signs and symptoms? |
-It's a chronic Inflammatory Disease of the joints.
-Signs and Symptoms: Sense of breathlessness -Tightening of the chest -Wheezing -Dyspnea -cough
Cause: Immune mediated airway inflammation
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2 Pharmacologic Classes for Asthma are? |
-Antinflammatory Agents (Glucocorticoids/Prednisone) -Bronchodialators (Beta2 Agonists/Albuterol) |
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Advantages of Inhalation Drug Therapy:
Name the 3 types: |
-Therapeutic effects are enhanced -Systemic effects are minimized -Relief of acute attacks rapid Three Types: -Metered-dose inhalers (MDI) wait 1 min btw puffs -Dry-powder inhalers (DPI) (easier to use than MDI) -Nebulizers: convert drug into mist |
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Glucocorticoids (budesonide, and fluticasone) |
Used for prophylaxis, must be done on a fixed schedule. Budesonide(pulmicort) -Considered most effective anti asthma drug available |
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Antiinflammatory drug: Glucocorticoids Mechanism of action: |
=Suppress Inflammation by: -Dec. release of inflammatory mediators -Dec. Infiltration of inflammatory cells(eosinophils, and leukocytes) -Dec. edema of airway mucosa |
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Glucocorticoid Adverse Effects: |
-Minor when taken acutely -Can be sever when taken long term(Adrenal Supression, Osteoporosis, Hyperglycemia, Weight gain, change in emotion, inc risk for infection, cushingoid appearance) THE BIG 3: Hyperglycemia, Inc. risk for infection, weight gain -Wean off slowly |
