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57 Cards in this Set

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Caffeine content in tea, soda, coffee, energy drinks, chocolate, and more

Tea: between 60 and 107 mg


Soda: 29 mg in a can of coke


Coffee: between 57 and 145 mg


Energy Drinks: ≈80 mg


Chocolate: between 6 and 12 mg per ounce


OTC Products: between 16 and 200 mg

Caffeine half life

5-6 hours

Caffeine effects

Good (appropriate amount): alert, better memory, stimulates hair growth, reduce fatty liver, increase semen volume, appetite suppressant


Bad (too much too fast/chronic): anxiety, insomnia, laxative, dependence, increased blood pressure, abnormal heartbeat, rebound fatigue, diuretic

How long until caffeine withdrawal

12-18 hours after last dose

Caffeine and alcohol

Can cause death

Caffeine

A xanthine stimulant found in coffee, tea, chocolate, soft drinks, and several medications.

Xanthines

A family of CNS stimulant drugs that includes caffeine, theophylline, and theobromine.

Theobromine

A xanthan stimulant found in chocolate.

Theophylline

A xanthine stimulant found in small amounts in tea. It is used as an antiasthma medication.

Adenosine

An inhibitory neurotransmitter that is blocked, or neutralized, by caffeine and other xanthines. The action on adenosine receptors in the body is the basis for the stimulant properties of these drugs.

Caffeinism

A dangerous state of behavioral and physiological overstimulation from a very large dose of caffeine.

Types of depressants and inhalants

. Barbiturates


. Benzodiazepines


. Alcohol


. Beta Blockers


. Common commercial products

Physiological effects of inhalants

Giddiness, euphoria, dizziness, slurred speech, drowsiness, loss of consciousness, double vision, ringing in ears, and hallucinations

Uses for benzodiazepines and barbiturates

Benzodiazepines: antianxiety


Barbiturates: hypnotic, sedative, anticonvulsant, and anesthetic

Benzodiazepine and barbiturate receptors

GABA receptors

Acute effects of benzodiazepines

Controls anxiety, long half life in the elderly, confusion and loss of memory in the elderly, and increased fall risk in the elderly

Chronic effects of benzodiazepines

Anxiety, insomnia, restlessness, and agitation

How to prevent inhalant abuse

. Restrict the sale of model-kit glue to minors


. Have unpleasant volatile chemicals in common inhalants

Prescription Drugs

Medicinal drugs available to the public only one approved by a medical professional and dispensed by a licensed pharmacist.

OTC Drugs

Medicinal drugs available to the public without the requirement of a prescription.

Dietary Supplements

Products distributed with the intention of supplementing the diet, that contain a vitamin, mineral, amino acid, herb or other botanical product, enzyme, organ tissue, metabolites, or any combination of these substances.

FDA

Food and drug administration, responsible for seeing the standards for safety, effectiveness, and honesty in labeling for the first two categories.

GRAS

Drug is safe.

GRAE

Drug is effective.

GRAHL

Drug is honestly labeled.

Analgesic

Relieves pain.

How long might it take a drug to be approved?

Several years

How much does it cost to go through the drug development process?

Several billion dollars

Phase I Trials

An experimental drug is administered to healthy volunteers to check for possible side effects and determine patterns of absorption and elimination.

Phase II Trials

An experimental drug is given to a small population of patients who have the medical condition for which the drug is considered a possible treatment.

Phase III Trials

An experimental drug is given to a large population of patients, through which issues of safety, effectiveness, and proper dosage levels are finalized.

Four types of OTC analgesic drugs

Aspirin, Tylenol, Advil, and Alleve

Biomedical Model

The theoretical position that mental disorders are caused by abnormal biochemical processes in the brain

Psychotropic

Alternative term for psychiatric

Typical Antipsychotics

Antagonist at dopamine D2 receptors

Atypical Antipsychotics

Also work at serotonin receptors

Tardive Dyskinesia

Side effect of typical antipsychotics with jerky movements

Monoamine Oxidase

Enzyme that breaks down dopamine, norepinephrine, or serotonin at their respective synapses in the brain

Bipolar Disorder

Mood disorder in which the patient swings back and forth between feelings of depression and mania.

Lithium

Treats bipolar disorder.

Deinstitutionalization

The social policy of encouraging mentally ill people to be treated in community-based programs rather than in large mental hospitals

Prevalence of schizophrenia

3 million people in the US (1%)

Schizophrenic brains

Enlarged cerebral ventricles

Dopamine Hypothesis

Schizophrenia results from excess synaptic dopamine it increased postsynaptic sensitivity to it.

1st generation antipsychotics

Chlorpromazine (thorazine) and haloperidol (haldol)

2nd generation antipsychotics

Clozapine (clozaril) and risperidone (risperdal)

3rd generation antipsychotics

Aripiprazole (abilify)

Typical antipsychotic side effects

Parkinson's-like symptoms and tardive dyskinesia

Atypical antipsychotic side effects

Weight gain and metabolic disorder

Theories of unipolar depression

MAO theory- reduced synaptic activity of norepinephrine and serotonin

1st generation antidepressants

MAOIs- restricted diet


Tricyclic antidepressants- affect cardiovascular system

2nd generation antidepressants

Slow serotonin reuptake (SSRIs)- Prozac (fluoxetine)

3rd generation antidepressants

Slow reuptake of serotonin and norepinephrine (SNRIs)- Cymbalta (duloxetine)

Primary Prevention

A type of intervention in which the goal is to forestall the onset of drug use by an individual who has had little or no previous exposure to drugs

Secondary Prevention

A type of intervention in which the goal is to reduce the extent of drug use in individuals who have already been exposed to drugs to some degree

Tertiary Prevention

A type of intervention in which the goal is to prevent relapse in an individual following recovery in a drug-treatment program

Evidence-Based

Primary and secondary people programs must be evaluated against a control group that did not receive the intervention