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30 Cards in this Set

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  • Back
What do antineoplastic agents do?
inhibit the new growth of cancer cells, neoplasms
What is meant by metastisized?
when the original cell group spreads to other areas
What are lymphocytes and what do they do?
a type of white blood cell that releases antibodies that attack and destroy antigens
What are the 2 primary types of lymphocytes?
T-cells and B-cells
Maintainence of the body's lymphocyte supply is largely performed by what?
the bone marrow
What type of cells do antineoplastic drugs target?
cells with fast growth rates
How do antimetabolites work?
they inhibit cell growth and replication by mimicking natural metabolites and taking their place within the cells; they inhibit the synthesis of cellular enzymes
How do alkyating agents work?
they interfere with mitosis, cell division, by binding with DNA and preventing cellular replication
What are nitrogen mustard gases known to do?
inhibit cellular growth and sperm counts while depressing bone marrow and damaging intestinal mucosa
What are nitrosureas and how do they work?
an alkyating agent that is lipid soluble and passes easily into the brain where they can treat brain cancers
What are some rapidly replicating cells in the body that can be affected by antineoplastics?
those of the GI tract, bone marrow, and hair follicles
What is Topoisomerase?
required for molecular cell growth, mitosis
What type of drug is Cyclophosphamide?
a neoplastic alkylating agent
What type of drug is Cisplatin?
a neoplastic alkylating agent
What type of drug is Busulfan?
a neoplastic alkylating agent
What type of drug is Methotrexate?
a neoplastic antimetabolite
What type of drug is 5-Fluorouracil?
a neoplastic antimetabolite
What type of drug is Mercaptopurine?
a neoplastic antimetabolite
What type of drug is Vincristine?
a neoplastic plant alkaloid
What type of drug is Paclitaxel?
a neoplastic plant alkaloid
What type of drug is Etoposide?
a neoplastic plant alkaloid
What type of drug is Tamoxifen Citrate?
a neoplastic anti-estrogen
What is the brand name for Busulfan?
Myleran
What is the generic name for Myleran?
Busulfan
What is the brand name for Etoposide?
Vepesid
What is the generic name for Vepesid?
Etoposide
What type of drug would have the stem -arabine in the word?
an antineoplastic drug
What type of drug contains the stem -mustine in the name?
antineoplastics
What type of drug contains the stem -rubicin in the name?
antineoplastics
What type of drug is Cisplatin?
an antineoplastic drug