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30 Cards in this Set
- Front
- Back
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What do antineoplastic agents do?
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inhibit the new growth of cancer cells, neoplasms
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What is meant by metastisized?
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when the original cell group spreads to other areas
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What are lymphocytes and what do they do?
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a type of white blood cell that releases antibodies that attack and destroy antigens
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What are the 2 primary types of lymphocytes?
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T-cells and B-cells
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Maintainence of the body's lymphocyte supply is largely performed by what?
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the bone marrow
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What type of cells do antineoplastic drugs target?
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cells with fast growth rates
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How do antimetabolites work?
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they inhibit cell growth and replication by mimicking natural metabolites and taking their place within the cells; they inhibit the synthesis of cellular enzymes
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How do alkyating agents work?
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they interfere with mitosis, cell division, by binding with DNA and preventing cellular replication
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What are nitrogen mustard gases known to do?
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inhibit cellular growth and sperm counts while depressing bone marrow and damaging intestinal mucosa
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What are nitrosureas and how do they work?
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an alkyating agent that is lipid soluble and passes easily into the brain where they can treat brain cancers
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What are some rapidly replicating cells in the body that can be affected by antineoplastics?
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those of the GI tract, bone marrow, and hair follicles
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What is Topoisomerase?
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required for molecular cell growth, mitosis
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What type of drug is Cyclophosphamide?
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a neoplastic alkylating agent
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What type of drug is Cisplatin?
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a neoplastic alkylating agent
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What type of drug is Busulfan?
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a neoplastic alkylating agent
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What type of drug is Methotrexate?
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a neoplastic antimetabolite
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What type of drug is 5-Fluorouracil?
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a neoplastic antimetabolite
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What type of drug is Mercaptopurine?
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a neoplastic antimetabolite
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What type of drug is Vincristine?
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a neoplastic plant alkaloid
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What type of drug is Paclitaxel?
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a neoplastic plant alkaloid
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What type of drug is Etoposide?
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a neoplastic plant alkaloid
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What type of drug is Tamoxifen Citrate?
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a neoplastic anti-estrogen
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What is the brand name for Busulfan?
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Myleran
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What is the generic name for Myleran?
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Busulfan
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What is the brand name for Etoposide?
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Vepesid
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What is the generic name for Vepesid?
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Etoposide
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What type of drug would have the stem -arabine in the word?
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an antineoplastic drug
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What type of drug contains the stem -mustine in the name?
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antineoplastics
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What type of drug contains the stem -rubicin in the name?
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antineoplastics
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What type of drug is Cisplatin?
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an antineoplastic drug
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