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10 Cards in this Set

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  • Back

catecholamines

any group of chemically related neurotransmitters as epinephrine and dopamine, that have similar effects on the sympathetic nervous system.

1. Alpha one receptor


2. alpha two receptor

1. in all sympathetic target organs except one, the heart. response- constriction of blood vessels, and dilation of pupils


2. at presynaptic adreneric neuron terminals, activation inhibits norepinephrine

1. beta one receptor


2. beta two receptor

1. in heart and kidneys. activation increases heart rate and force of contraction of heart, increases release of renin


2. in all sympathetic target organs except, inhibit smooth muscle, bronchodilation

1. nicotinic

1. in sympathetic and parasympathetic nervous system divisions at the ganglionic synapse. response. response- stimulate smooth muscle, stimulate gland secretion

muscarinic

in parasympathetic target organs except the heart. response- stimulate smooth muscle, stimulate gland secreation, in heart: decrease heart rate and force contraction.

1. sympathomimetic


2. parasympatholytic

1. stimulates sympathetic nervous system


2. stimulates the parasympathetic nervous system.

1. prototype drug: phenylephrine (neo- synephrine)


2. mechanism of action:


3. primary use



1. sympathomometics


2. stimulate the sympathetic nervous system directly/indirectly


3. depends on which receptors activated, alpha 1, alpha2, beta1, beta 2.

1. prototype drug: prozosin (monipress)


2. mechanism of action


3. primary use


4. adverse effects

1. adrenergic- blocking agents


2. to inhibit the sympathetic nervous system


3. hypertension, dysrhythmias, angina, heart failure, benign prostatic hypertrophy, narrow angle glaucoma


4. dizziness, drowsiness, headache, loss of energy and strength, palpitations, dry mouth.

1. prototype drug: bethanechol (urecholine)


2. mechanisms of action


3. uses

1. cholinergic agents(parasympathommimetic), not good for the lungs


2. to activate the parsympathetic nervous system


3. guacoma, urinary retention, myasthenia gravis, Alzheimer disease,

1. prototype drug: atropine (atropair, atropisol)


2. mechanism of action


3. primary use


4. adverse effects

1. cholinergic- blocking agents


2. to inhibit the parasympathetic nervous system


3. peptic ulcers, irritable bowel syndrome, mydraisis and cycloplegia during eye examination, bradycardia, preanestetic, asthma.


4. tachycardia, CNS stimulation, urinary retention, dry mouth, dry eyes, decreased sweating, photophobia.