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32 Cards in this Set

  • Front
  • Back
Penicillin - action
bactericidal - inhibit cell wall formation
Penicillin -
Which bacteria does it affect?
Penicillin - contraindications
hx of allergic reaction to penicillin or cephalosporin
Penicillin -
drug interaction
effectiveness decreased when given with tetracyclines
Penicillin - adverse affects
allergic reactions - varied from rashes to anaphylaxis
GI distress - black, furry tongue, dysphasia, prolonged bleeding time
can progress to renal failure
Penicillin - Nursing Considerations
monitor for allergic reactions
need additional contraception throught therapy
report unusal bleeding
take on an empty stomach (1 hour before or 2 hours after)
take with water - avoid fruit juices and soda (acid)
Cephalosporin - action
bactericidal - inhibit cell wall formation

similar to penicillins in structure and activity
Cephalosporin - Which bacteria does it affect?
gram negative
Cephalosporin - contraindications
hx of allergic reaction to penicillin or cephalosporin
hx renal failure - leads to toxicity
pregnancy, lactation
Cephalosporin - drug interaction
alcohol - causes tremors, NVD, hypo&hypertension
anticoagulants - increases bleeding time
Cephalosporin - adverse affects
Considered the safest type of antibiotic
allergic reactions - rash, pruritus, joint inflammation
GI effects - NVD
bleeding tendencies, nephrotoxicity
Cephalosporin - Nursing Considerations
monitor for sensitivity
monitor renal and hepatic function
monitor prothrombin times
take with small meal/snack
avoid alcohol
report bleeding
Sulfonamide - action
bacteriostatic (inhibits new growth - does not affect pre-existing bacteria)
Sulfonamide - Which bacteria does it affect?
Sulfonamide - contraindications
hx allergy to sulfas, thiazide diruetics
hx within 2-3 weeks of an acute gout attack
hx peptic ulcer or renal disorder
Sulfonamide - drug interactions
etoh - increases BUN levels
Sulfonamide - adverse effects
sensitivities - rash, fever, etc.
crystalluriea resulting in renal damage, anaphylaxis,
potential for nephrotoxicity
Sulfonamide - nursing considerations
take with empty stomach with full glass of h2o
monitor CBC, renal and liver function tests, gluscose levels
increase fluid intake
avoid sunlight
Aminoglycoside - action
betericidal - prevent protien synthesis
Aminoglycoside - Which bacteria does it affect?
some protozoa
Aminoglycoside - contraindications
hx known allergies
hx renal hepatic disease
preexisting hearing loss
active herpes
myasthenia gravis
Aminoglycoside - drug interactions
neuromuscular blocking agent leads to peripheral nerve toxicity and paralysis
diuretics leads to ototoxicity, nephrotoxicity, neurotoxicity
anticoagulants can increase bleeding time
Aminoglycoside - adverse effects
nephrotoxicity, ototoxicity (dizziness, tinnitus, vertigo, nystagmus, hearing loss)
Aminoglycoside - nursing considerations
monitor renal function tests, cbcs for bbone marrow suppresion
increase fluid intake
report bleeding, HA loss of hearing
signs of ototoxicity
dizziness, tinnitus, nystagmus, ataxia, hearing loss
signs of nephrotoxicity
proteinuria, increased BUN and creatinine levels and urinary casts
Tetracycline - action
bacteriocidal in high doses
Tetracycline - which bacteria does it affect?
"broad spectrum"
gram +
gram -
Tetracycline - contraindications
hx renal and hepatic dysfunction, bile duct obstruction
caution with asthma, myasthenia gravis, malnourished
Tetracycline - interactions
compromised absorption with dairy products and antacids
penicillin absorption is decreased
digitalis increased risk for digitalis toxicity
Tetracycline - adverse effects
NVD, photosensitivity
Tetracycline - nursing considerations
monitor cbc, liver, kidney function
sunscreen without PABA
adequate hydration
space antacid doses at least 3 hours