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9 Cards in this Set
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- Back
- 3rd side (hint)
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Epoprostenol
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PGI2 analog
platelet agg INHIBITOR vasodilator |
primary pulmonary hypertension infused thru portable infusion pump
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Trepostinil
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PGI2 analog
platelet agg INHIBITOR vasodilator |
longer half life than epoprostenol
vasodilator for pulmonary hypertension |
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Alprostadil - Pediatrics
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PGE1 analog
smooth muscle relaxant |
Opens ductus arteriosus in neonates
-- patency depends on local pg synthesis Continuous IV infusion Adv: apnea, brady-, hypotension |
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Alprostadil - Men
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Corrective agent for impotence
Induces erection |
Urethral suppository pellet
Intracernosal inj penile pain is freq SE replaced by Viagra |
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Dinoprostone
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PGE2 analog
Oxytoxic Promotes uterine contractions Can terminate pregnancy at any stage -induces abortion in 2nd trimester |
vaginal suppository, gel, CR prep
Softens cervix Shortens delivery time GI SE: N&V,D, cramping (less GI with CR prep) |
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PGF2alpha Analog
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Induces 2nd trimester abortion
Controls postpartum hemorrhage Induce labor |
IM inj
GI problems -too much toxicity when oral |
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Misoprostol
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PGE1 deriv
Cytoprotective Prevention of NSAID induced peptic ulcers Need to replenish because of NSAID admin |
Duration of action: 3 hrs
Effective in healing gastric ulcers SE: ab cramping, diarrhea DO NOT USE IN PREGNANT WOMAN |
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Latanoprost
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PGF2alpha deriv
Inc outflow |
Topically
No major SE Darken iris color possible stinging, burning, tearing |
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Additional PGF2alpha drugs
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Bimatoprost
Travoprost Unoprostone |
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