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10 Cards in this Set

  • Front
  • Back

Nsaid Melvin m said



It's the aliens planet


Aspirin is an ass pear he is stubborn and he is irreversible



Ibuprofen


Eye ball with the fin



Diclofenac


Non selective


Dice clone



Indomethacin


In the doughnut



Naproxen


AnalogyIt's the aliens planet Aspirin is an ass pear he is stubborn and he is irreversible


Ibuprofen


Eye ball with the fin



Diclofenac


Dice clone



indomethacin


the doughnut



Naproxen


Napping ox



Mefenamic acidMetal fence



CelecoxibSelective inhibitor so it is isolated


Or sell e cock xib



AcetaminophenAce with the finSo it's not a true nsaid so it has green aura


Inhibitor at cns level



Mefenamic acid


Metal fence



Celecoxib


DiclofenacDice cloneIndomethacinIn the doughnut NaproxenNapping oxMefenamic acidMetal fenceCelecoxibSelective inhibitor so it is isolatedOr sell e cock xibAcetaminophenAce with the finSo it's not a true nsaid so it has green aura


Selective inhibitor so it is isolated


Or sell e cock xib



Acetaminophen


Ace with the fin


So it's not a true nsaid so it has green aura






Contra


N


S



G i diseases


But with protein pump inhibitor itz good for ulcer



Cardiovascular effect


Like increase blood pressure and swelling in leg



Taking blood thinners warafin and coumadin


Indication


AntiInflammation


Antipyretic


Anti



Mechanism



By Cox 1 physiological inhibition



Cox 2 from inflammation


Acetaminophen


CNS



But most medicine inhibit both cox



Sedative Hypnotic and anxiolytic


Effects


Adverse effects


Benzodiazepine kebin


Barbiturates roopali


Alcohol



Effects


Paradoxical disinhibition


CNS is always glutamate and


Subcortical nuclei



So therefore excitation


Drunk people talk a lot


Agitated restlessness



.


Sedation and anxiolysis


.


Hypnosis


.


Anesthesia


.


Medullary depression


.


Coma


Death



Benzodiazepine much safer than barbiturates



GABA a


Due to different binding sites


Benzodiazepine gamma



Gaba a chlorine increase


Gaba b potassium increase




Adverse effects


Sedation


Confusion


Psychomotor impairment


Like slow reaction time

N

N

Acute treatment for gout

Nsaid like ibuprofen and indomethacin



Colchicines



And also


Steroid


Prednisone




Not probenecid


It's only for long term not acute attack

Adrenergic receptor


Alpha


And beta




























Beta 1 heart kidneyBeta 2 lung liver vascular and skeletal muscleBeta 3 fat cells First generationNon selective B1 and b2Not for pregnancySecond generation Cardio selective Lung diseasesAnd diabetesNot for asthma or copdThird generation VasodilationMechanismReduce heart rate Decrease sinus rhythm


Adverse effects


Breathing difficulties


Increase in heart rate


Drowsiness


Not


Muscle cramps and pain



If not sweating and tachycardia


Insulin special care

massaging the injection site increases absorption



Also glucosamine does not really but CAn interfere with absorption


Glucosamine for cartilage



And injection at abdomen not leg


Ace inhibitor side effects and mechanism

Volume reducing drugs


Ace 1


Pril


Drugs



Loop diuretics


Imide drugs



Thiazide



Potassium sparing



Bouncer


Aldoestrone


Closes door and make sure no fluid comes out



President


Renin


Upper management in adrenals and he calls the Aldoestrone to close door so we can make money


And talks to assistant Angie 1 2/and to Aldoestrone




Managers


Girls


Angie 1 2



Door is the kidney



Every management let's girls for naughty na girls to get guys or water in the club



In order to preserve the water



But when you have Aldoestrone receptor blockers


Arb then bp hr all decreases



So drugs name


Pril


Sarton



.side effect


Ace inhibitor


Is headache


Dizziness


postural hypotension



Except


Potassium depletion same as thiazide and loop diuretics

Penicillin

Gram positive cocci bacteria


And gram negative



Penicillin


Augmentin


Or amoxicillin



People are allergic to it and get red itchy rashes so he should contact the doctor

Muscular relaxant

Types


Central


Peripheral



1.Spasticity- baclofen


Descending pathways of spinal cord


Some effect muscle weakness



2.Acute muscle spasm


Trauma


Inflammation


- mephenezine


Cyclobenzaprine



3. Spastic and acute drugs


Diazepam


Or


Tizanidine



Peripheral acting



1.Oxytocin


(Breast and uterine delivery baby)



2. Ato


Depolarization


Succinylcholine


Rapid onset and relaxation


Trauma


Avoid patients with hyperkalemia


Spinal cord denervation disease


Sodium enter and k leaves


So less motor activity


And increase k so also not for burns patient



Also causes bradycardia




Non depolarization


Binds to one receptor


Onium



Short-rocuronium


Medium- cisatracurium


Fir renal hepatic patients


Long-pancuronium



Peripheral and central nervous system



Cholinergic


Anticholinergic


Effects


Types


3 s


See


Pie


****


Bam slm



Bronchodilator


Beta 2 agonist


Pium


Anticholinergic


Methyl xanthine



Sl



Peripheral


Autonomic - s n s



And p s n s


Cholinergic drugs


Acetylcholine


to organs



Indirectly to acetylcholine esterase for Alzheimer's disease


Directly to organsIndirectly to acetylcholine esterase for Alzheimer's diseaseIncreases CNSEye constrictionG i stimulation



Increases


CNS


Eye constriction


G i stimulation


Urinary bladder


Muscle tone and strength for myasthenia gravis



Anticholinergic


Block parasympathetic response of body


Side effects


Blind as a bat


Dilation pupils


Red as a beat


Flushed skin


Hot as a hare


For hypothermia


Dry as a bone


Dry skin, mucous membranes


Mad as a hater


Hallucinations


Bloated as a toad


Urinary retention


Heart runs along


Tachycardia




Sludge


Decrease heart rate


Av block


Increase brochial secretion


Antidote atropine




Types of anticholinergic


1. Antimuscarinic agents


Atropine


2. Anti nicotinic agents


3. Neuromuscular blocker



Contraindicated


Asthma


Peptic ulcee


Coronary artery disease


Hyperthyroidism



Anticholinergic


Block at muscarinic


Adverse effectsSludgeDecrease heart rateAv blockIncrease brochial secretionAntidote atropineContraindicatedAsthmaPeptic ulceeCoronary artery diseaseHyperthyroidismAnticholinergicBlock at muscarinicCNS - decrease muscle rigidity Parkinson'sHeart increase heart rateLungs -reduce secretion and bronchial dilationAdverse effectsCNS - excessive stimulation that is confusion restlessness followed by respiratory depression and comaTachycardia


CNS - decrease muscle rigidity Parkinson's


rate


Lungs -reduce secretion and bronchial dilation



CNS - decrease muscle rigidity Parkinson'sHeart increase heart rateLungs -reduce secretion and bronchial dilationAdverse effectsCNS - excessive stimulation that is confusion restlessness followed by respiratory depression and comaTachycardia


Adverse effects


Heart increase heart rateLungs -reduce secretion and bronchial dilationAdverse effectsCNS - excessive stimulation that is confusion restlessness followed by respiratory depression and comaTachycardia


CNS - excessive stimulation that is confusion restlessness followed by respiratory depression and coma



Tachycardia



Eg. Atropine


Ipratropium or atrovent for copd



Parkinson's benztropine



Somatic nervous system