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21 Cards in this Set

  • Front
  • Back
Name all the drugs that act as a PDE inhibitors.
Papaverine
Sildenafil
Theophylline
Caffeine
Name all the drugs that affect ACH release/synthesis
botulinum toxin

hemicholinium
tetanus toxin
alpha-latrotoxin
Name all the drugs that are cholinergic agonists
acetylcholine
methacholine
carbachol
bethanechol
succinylcholine
pilocarpine
cevimeline
Name the drugs that are used to treat glaucoma.
pilocarpine
betaxolol
timolol
latanoprost
epinephrine
dipivefrin
apraclonidine
acetazolamide
dorzolamide
isofluophate
echothiophate
mannitol
Name the Carbamate ACHase inhibitors.
Physostigmine
Donepezil
neostigmine
pyridostigmine
edrophonium
carbaryl
Name the OP ACHase inhibitors
Dimpylate
Isofluophate
Parathion
Malathion
Echothiophate
Name the drug use to the treat OP poisoning.
Pralidoxime
Name the tertiary muscarinic antagonists.
Atropine
Scopolamine
Cyclopentolate
Tropicamide
Benztropine
Trihexyphenidyl
Dicyclomine
Hyoscyamine
oxybutynin
tolterodine
solifenacin
darifenacin
diphenhydramine
Name the quaternary muscarinic antagonist.
N-methylatropine
methscopolamine
ipratropium
glycopyrrolate
propantheline
trospium
Name the nicotinic receptor agonist.
nicotine
succinylcholine
Name the adrenergic agonists
NE
Epi
DA
Dobutamine
Isoproterenol
Salmeterol
Terbutaline
Albuterol
Pirbuterol
Ritodrine
Phenylephrine
Oxymetazoline
Tyramine
Amphetamine
Phenylpropanolamine
Ephedrine
Pseudoephedrine
Name the ganglionic blocking drugs
Trimethaphan
Mecamylamine
Name the alpha antagonists.
Phenoxybenzamine
phentolamine
prazosin
tamsulosin
labetalol
yohimbine
ergotamine, dihydroergotamine
Name the drugs used to treat impotence
Phentolamine
Papaverine
Alprostadil
SIldenafil
Name the drugs used as B antagonists
Betaxolol
atenolol
metoprolol
esmolol
propanolol
timolol
labetalol
Name the drugs used as sympatholytic drugs
Alpha methyldopa
Reserpine
Guanethidine
Name the drugs that alter NE metabolism
Cocaine
Botulinum Toxin
MOA
- Binds to surface protein and transported into cholinergic neurons
-protease activity hydrolyzes the proteins involved in the synaptic storage and exocytotic release of ACH
- Neurotransmission ceases in the nerve that supply NMJ

Therefore: muscle paralysis

Therapeutic use:
-Laryngeal dystonia
-strabismus
-hemifacial spasm
Tetanus Toxin
MOA:
Prevent the release of inhibitory NT at the spinal cord.

Causes: Spastic paralysis
Hemicholinium
Prevents Ach synthesis by blocking choline uptake.
Drugs affecting degradation of ACH
1. Slowly-reversible carbamate inhibitors of Achase
2. Irreversible OP inhibitors of AcHAse