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23 Cards in this Set
- Front
- Back
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Beta Blockers (-olols)
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Block B receptors, slow Heart Rate
Hypotension Fatigue Erectile Dysfunction Bronchoconstriction Nightmares |
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Calcium Channel Blockers (-'pines, -'mils)
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Block Calcium channels, slow conduction and SmM relaxation
Gum Hypertrophy Flushing Oedema Hypotension Bradycardia |
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Nitrates
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Vasodilation of Collaterals
Headaches Hypotension |
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Statins
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Block HMG CoA Reductase, reduce Cholesterol
Rhabdomyolysis Deranged LFTs Muscle Aches Abdominal Pain |
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Potassium Antagonists
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N.O. Donor, venodilation, increase K+ and hyperpolarization
Flushing Oedema Dizziness |
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Aspirin
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Block COX, inhib platelet aggregation
Gastric ulcers Bronchospasm Liver/Kidney Toxicity |
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Clopidogrel
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Block ADP, inhib platelet aggregation
Ulcers Itching |
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GPIs (2a/3b Inhibitors)
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Block 2a/3b, inhib platelet aggregation
Bleeding Thrombocytonpenia |
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Heparin
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Thins Blood
Heamorrhages Bleeding Thrombosis |
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Fondaparinux
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Thins blood
Bleeding Thrombocytopenia |
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Bivalirudin
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Inhib thrombin, inhib platelet aggregation
N&V Backpain Hypotension Bleeding |
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Adenosine
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Inhib alpha receptors, increase intracellular K+ and decrease Ca+, slows conduction
Transient Flushing Chest Pain SOB Nausea Lightheadedness Chocking Sensation |
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Digoxin
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Inhib Na/K+ pump, indirectly inhib Na/Ca+ pump, increase Na and Ca intracellularly, slows conduction
Arrhythmia Nausea Decrease Appatite Yellow Vision Confusion Gynaecomastia Hypokalaemia |
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Amiodarone
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Alters ion permeability, decreasing intracellular Ca+ and increasing K+, slows conduction
Bradycardias Hypokalaemia HF Liver/Kidney Disturbance Decrease LV Function |
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Lignocaine
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Block Na channels, block AP, no sensation
Dizziness Pins and Needles Drowsiness |
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Flecainide
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Block Nav 1.5 channel, prolong cadiac AP, decrease cardiac contractility, decrease EF
Dizziness Visual Disturbances N&V |
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Magnesium Sulphate
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Ca channel antagonist, decreasing intracellular calcium, slows conduction, stimulate PGs and NO production
Diarrhoea N&V Thirst Flushing Hypotension Drowsiness |
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Atropine
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Musc. ACh antagonist, increase HR
Dry Mouth Thirst Blurred Vision Dry Skin Tachycardia Difficulty Micturating |
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Beta-2 Agonists
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Bind to Beta receptors, increase cAMP, relax SmM
Positively Chronotropic SkM fine tremor Relax Uterine Muscle Hypokalaemia |
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Corticosteroids
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Musc. Antagonist, Decrease cGMP,
Inhib Bronchoconstriction and mucus sec. Mucus Secretion Dry Mouth Dysphonia Skin Thinning Weight Gain DM Infection Sk Growth Oral Candidiasis |
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Leukotriene Antag.
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Inhib Leukotriene, decrease broncho-constriction and inflammation
GI Dist Headaches Hypersensistivity Vivid Dreams |
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Anti-IgE
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Inhib IgE antibodies, reduce inflammation
Headache Infection/URTIs Anaphylaxis Fainting, decrease BP |
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Theophyllines
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Inhib PDE, increase cAMP
Nausea and Vomm Arrhythmias GI Upset Fits |
