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21 Cards in this Set

  • Front
  • Back

the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients, while integrating clinical experience with the best available evidence from systematic research

evidence-based medicine (EBM)

document and communicate experience; share ideas, programs, treatments, unusual events, and observations; begin research for explanations

descriptive evidence

examine etiology, cause, efficacy, using the strategy of comparisons

explanatory evidence

evaluate efficacy of therapeutic, educational, administrative interventions; investigator controls allocation

experimental evidence

seek causes, etiologies, predictors, better diagnosis; investigator observes nature

observational evidence

descriptive articles

case series/reports

explanatory studies

experimental studies and observational studies

experimental studies

randomized controlled trails (RCT)

observational studies

cohort studies, case-control studies, cross-sectional/surveys

goal is to document events, observation, and activities

descriptive articles

it worked on one patient

case report

it worked on a bunch of patients

case series

predictor variable; variable which precedes and is presumed to cause or be associated with the outcome

independent variable

outcome variable; the response to the independent variable

dependent variable

strongest design to determine cause and effect; participants receive an interventional; evaluate efficacy of therapeutic, educational, administrative interventions

experimental: randomized controlled trials (RCT)

investigators observe the events without any intervention; establish etiologies, predictors, better diagnosis

observational: cohort, case-control, cross sectional/survey studies

half get drug, half get placebo; the "gold standard" for comparing interventions

randomized controlled trials (RCT)

a group of subjects initially identified as having one or more characteristics in common who are followed over time in an effort to determine the factors leading to different outcomes; commonly prospective but can be retrospective

cohort (follow-up studies)

the number of new events by the number of individuals being observed

relative risk (RR)

a group of people with a disorder (cases) and a group of people free of the disorder (controls) are compared to determine whether differences in the groups' previous exposures, experiences, risk factors, etc could explain their different outcomes; retrospective only; conducted on rare diseases or condition to determine a common factor in th past that can be associated with a disease or condition

case-control studies

the event odds in the cases divided by the event odds in the control group

odds ratio (OR)