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14 Cards in this Set
- Front
- Back
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Mechanism of Action for Nicotine (nik’ oh teen)
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Agonist at both NN and NM receptors
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Mechanism of Action for Mecamylamine (mek a mil’ a meen)
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Selectively antagonizes NN receptors. It is the only ganglionic blocker currently available in the United States.
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Mechanism of Action for Succinylcholine (suks in il koe’ leen)
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Succinylcholine is depolarizing agonist of nicotinic acetylcholine (ACh) receptors at neuromuscular junctions, making it a muscle relaxant.
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Mechanism of Action for Tubocurarine Chloride (too boh kyoo rahr’ enn)
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Competitive antagonist of nACh receptors, especially at neuromuscular junctions, having a long duration of action (80-120 min).
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Mechanism of Action for Atracurium Besylate (a tra kyoo’ ree um)
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Competitive antagonist of nACh receptors, especially at neuromuscular junctions, having an intermediate duration of action (30 - 60 min).
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Mechanism of Action for Cisatracurium Besylate (sis’ a tra kyoo” ree um)
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Competitive antagonist of nACh receptors, especially at neuromuscular junctions, having an intermediate duration of action (25 - 45 min).
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Mechanism of Action for Mivacurium Chloride (mye va kyoo’ ree um)
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Competitive antagonist of nACh receptors, especially at neuromuscular junctions, having a short duration of action (12 - 18 min).
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Mechanism of Action for Doxacurium Chloride (doks a kyoo’ ri um)
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Competitive antagonist of nACh receptors, especially at neuromuscular junctions, having a long duration of action (90 - 120 min).
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Mechanism of Action for Pancuronium Bromide (pan kyoo roe’ nee um)
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Competitive antagonist of nACh receptors, especially at neuromuscular junctions, having a long duration of action (120 - 180 min).
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Mechanism of Action for Rocuronium Bromide (roe kyoor oh’ nee um)
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Competitive antagonist of nACh receptors, especially at neuromuscular junctions, having an intermediate duration of action (30 - 60 min).
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Mechanism of Action for Vecuronium Bromide (ve kyoo’ roe ni um)
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Competitive antagonist of nACh receptors, especially at neuromuscular junctions, having an intermediate duration of action (60 - 90 min).
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Mechanism of Action for Baclofen (bak’ loe fen)
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GABA-B agonist; Facilitates spinal inhibition of motor neurons
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Mechanism of Action for Dantrolene (dan’ troe leen)
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Blocks RyR1 Ca2+-release channels in the sarcoplasmic reticulum of skeletal muscle
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Mechanism of Action for Botulinum Toxin A (bott’ you lye num)
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Cleaves SNAP-25 at NMJ, disrupting SNARE complexes, thereby preventing acetylcholine release
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