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61 Cards in this Set

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What drugs have an FDA indication of: for the management of moderate to severe pain (#7) ?
oxycodone HCl (CR), oxycodone (IR), morphine sulfate, tramadol HCl, acetaminophen with codeine, oxycodone with acetaminophen, hydrocodon bitartrate with acetaminophen,
What drugs have an FDA indication of: painful musculoskeletal conditions (#2)?
cyclobenzaprine HCl, carisoprodol (muscle relaxant)
What drug has an FDA indication for opiod dependence?
Buprenorphine with naloxone
what drug has an FDA indication for tension headaches?
Butalbital with acetaminophen and caffeine
What drug has an FDA indication for just rheumatoid arthritis?
diclofenac sodium
What drugs have an FDA indication for both rheumatoid arthritis and osteoarthritis (#2)?
meloxicam, indomethacin
What is the FDA indication of lidocaine?
post herpetic neuralgia
What drug has an FDA indication for just osteoarthritis?
celecoxib - NSAID
What drugs have an FDA indication of: mild to moderate pain and primary dysmenorrhea (#2)?
naproxen and ibuprofen (both NSAIDs)
What drugs are NSAIDs (#6)?
meloxicam, celecoxib, indomethacin, diclofenac, naproxen and ibuprofen
What is the pharmacology of carisoprodol?
work centrally in the spinal cord or descending reticular formation to produce muscle relaxation
What is the pharmacology of cyclobenzaprine?
acting on the brain stem in the CNS - reduction of somatic motor activity
What is the pharmacology of lidocaine?
combines with fast sodium channels to inhibit repolarization
What drug is a partial opiod agonist/antagonist? and what do these parts do?
Burprenorphine with naloxone - agonist of the mu-opiod receptor and antagonist of the kappa-opiod receptor
What is the pharmacology of butalbital with acetaminophen and caffeine?
butalbital - inhibition of conduction in the reiticular formation (thalamus); acetaminophen - inhibits synthesis prostaglandin; caffeine - inhibits phosphodiesterase increasing accumulation of cAMP
What drugs inhibit cyclooxygenase resulting in decreased biosynthesis of prostaglandin (#9)?
meloxicam, indomethacin, celecoxib, ibuprofen, naproxen, diclofenac sodium, any drug with acetaminophen (tylenol, vidocin, percocet)?
Which drugs are paired with acetaminophen and act on central opiate receptor?
oxycodone (percocet), hydrocodone bitartrate (vicodin), codeine (tylenol/phenaphen)
Which drugs (not paired with acetaminophen) act on the central opiod receptor?
fentanyl, oxycodone HCl (CR/IR), morphine sulfate, and methadone HCl
What is the pharmacology of tramadol?
binds to m-opiod receptor and inhibition of reuptake of serotonin and norepinephrine.
What precaution of tramadol makes it unique?
use with caution in patients with epilepsy or history of seizures
What drugs produce an adverse effect of constipation (#4)
buprenorphine with naxolonem morphine sulfate, oxycodone (IR/CR)
What drugs produce an adverse effect of drowsiness and dizziness (#8)?
methadone, oxycodone with acetaminophen, acetaminophen with codeine, hydrocodone bitartrate with acetaminophen, butalbital (with acetaminophen and caffeine), carisopodol, tramadol, and cyclobenzaprine
What are the adverse effects of fentanyl?
hypoventilation, hypotension and hypertension
What are the adverse effects of lidocaine?
commoly topical in nature: edema, bruising, erythema, discoloration ect.,
What is a unique adverse effect of ibuprofen?
rash
What drugs produce adverse effects generally gastrointstinal in nature (#2)?
meloxicam and indomethacin
what are the adverse effects of celecoxib?
similar to placebo - dyspepsia, diarrhea, abdominal pain
what are the adverse effects of diclofenac?
nausea, indigestion - typical of class
what are the adverse effects of naproxen?
shortness of breath, indigestion, tinnitus
what would you tell a patient who is taking fentanyl?
patches should be placed to non-irratated skin, not below knees or elbows. hair on site should be clipped and not shaven. do not use soaps to clear area prior to using.
what would you tell a patient using lidocaine patches?
do not use external heat sources such as electric blankets or heating pads over the lidoderm patch
what would you tell a patient using celecoxib?
promptly report any signs of ulcerations and bleeding (i.e, intense GI pain or dark stool) to a physician
what would you tell a patient using oxycodone (CR) or morphine sulfate?
tablet is not to be crushed, broken, or chewed - this may cause a rapid release of the drug and cause toxic effects
What drugs may cause drowsiness and thus the patient should use caution when operating a motor vehicle or when mental alertness is required?
suboxone, oxycodone (IR), methadone, percocet, tylenol, carisoprodol, vicodin, fioricet, tramadol, cyclobenzaprine
what drugs should the patient be: "compliant for up to 2 weeks, because it may take up to 2 weeks to have noticeable improvement in arthritic conditions" (#4)?
naproxen, indomethacin, meloxicam, ibuprofen
what would you tell a patient on diclofenac sodium?
concurrent ingestion of alcohol will increase ulcerogenic effects
What drugs come in the form of capsules (#3)?
celecoxib, cyclobenzaprine (or tab), and indomethacin (powder/supp)
what dosage form is buprenorphine with naloxone?
tablet or film: both SUBLINGUAL!
what is the brand name of buprenorphine with naloxone?
suboxone
what is the brand name of indomethacin?
indocin
what is the brand name of cyclobenzaprine (#3)?
amirix, flexeril, fexmid
what are the other brand names for vicodin?
lortab, lorcet, norco
what is the brand name of carisoprodol?
soma
what is the brand name for oxycodone HCl (immediate release)?
roxicodone
what is the brand name of meloxicam
mobic
what is the brand name of diclofenac sodium?
voltaren
what is the brand name of morphine sulfate?
MS Contin
what is the brand name of Oxycodone HCl (controlled release)?
Oxycontin
what is the brand name of tramadol?
ultram, ryzolt
what is the brand name of butalbital with acetaminophen and caffeine?
Fioricet, esgic-plus
which drugs are in the class of "analgesics" (#2)?
butalbital with acetaminophen and caffeine, and tramadol HCl
which drugs are in the class "muscle relaxant" (#2)?
cyclobenzaprine, carisoprodol
what is the drug class of buprenorphine with naloxone?
agent for opioid dependence
What drugs have a contraindication of "hypersensative to NSAIDs" (#6)?
All NSAIDS - naproxen, ibuprofen, meloxicam, indomethacin, celebrex, and dicofenac Na
What drugs have a contraindication of "respiratory depression" (#3)?
oxycodone (IR/CR), morphine
what drugs have a contraindication of "hypersensative to any component of the drug" (#7)?
fiorecet, suboxone, percocet, lidocaine, celecoxib, fentanyl, and tramadol
What drug has should be used with caution in patients who are prone to hyperventilation?
fentanyl
what is methadone contraindicated for (dosage form)?
injection
what is cyclobenzaprine contraindicated for?
congestive failure, hyperthyroidism
what is carisoprodol contraindicated for?
acute intermittent porphyria
what drugs should you use with caution for "intracranial pressure" (#2)?
anything with oxycodone or acetaminophen