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61 Cards in this Set
- Front
- Back
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What drugs have an FDA indication of: for the management of moderate to severe pain (#7) ?
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oxycodone HCl (CR), oxycodone (IR), morphine sulfate, tramadol HCl, acetaminophen with codeine, oxycodone with acetaminophen, hydrocodon bitartrate with acetaminophen,
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What drugs have an FDA indication of: painful musculoskeletal conditions (#2)?
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cyclobenzaprine HCl, carisoprodol (muscle relaxant)
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What drug has an FDA indication for opiod dependence?
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Buprenorphine with naloxone
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what drug has an FDA indication for tension headaches?
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Butalbital with acetaminophen and caffeine
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What drug has an FDA indication for just rheumatoid arthritis?
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diclofenac sodium
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What drugs have an FDA indication for both rheumatoid arthritis and osteoarthritis (#2)?
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meloxicam, indomethacin
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What is the FDA indication of lidocaine?
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post herpetic neuralgia
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What drug has an FDA indication for just osteoarthritis?
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celecoxib - NSAID
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What drugs have an FDA indication of: mild to moderate pain and primary dysmenorrhea (#2)?
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naproxen and ibuprofen (both NSAIDs)
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What drugs are NSAIDs (#6)?
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meloxicam, celecoxib, indomethacin, diclofenac, naproxen and ibuprofen
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What is the pharmacology of carisoprodol?
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work centrally in the spinal cord or descending reticular formation to produce muscle relaxation
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What is the pharmacology of cyclobenzaprine?
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acting on the brain stem in the CNS - reduction of somatic motor activity
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What is the pharmacology of lidocaine?
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combines with fast sodium channels to inhibit repolarization
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What drug is a partial opiod agonist/antagonist? and what do these parts do?
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Burprenorphine with naloxone - agonist of the mu-opiod receptor and antagonist of the kappa-opiod receptor
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What is the pharmacology of butalbital with acetaminophen and caffeine?
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butalbital - inhibition of conduction in the reiticular formation (thalamus); acetaminophen - inhibits synthesis prostaglandin; caffeine - inhibits phosphodiesterase increasing accumulation of cAMP
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What drugs inhibit cyclooxygenase resulting in decreased biosynthesis of prostaglandin (#9)?
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meloxicam, indomethacin, celecoxib, ibuprofen, naproxen, diclofenac sodium, any drug with acetaminophen (tylenol, vidocin, percocet)?
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Which drugs are paired with acetaminophen and act on central opiate receptor?
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oxycodone (percocet), hydrocodone bitartrate (vicodin), codeine (tylenol/phenaphen)
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Which drugs (not paired with acetaminophen) act on the central opiod receptor?
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fentanyl, oxycodone HCl (CR/IR), morphine sulfate, and methadone HCl
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What is the pharmacology of tramadol?
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binds to m-opiod receptor and inhibition of reuptake of serotonin and norepinephrine.
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What precaution of tramadol makes it unique?
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use with caution in patients with epilepsy or history of seizures
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What drugs produce an adverse effect of constipation (#4)
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buprenorphine with naxolonem morphine sulfate, oxycodone (IR/CR)
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What drugs produce an adverse effect of drowsiness and dizziness (#8)?
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methadone, oxycodone with acetaminophen, acetaminophen with codeine, hydrocodone bitartrate with acetaminophen, butalbital (with acetaminophen and caffeine), carisopodol, tramadol, and cyclobenzaprine
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What are the adverse effects of fentanyl?
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hypoventilation, hypotension and hypertension
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What are the adverse effects of lidocaine?
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commoly topical in nature: edema, bruising, erythema, discoloration ect.,
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What is a unique adverse effect of ibuprofen?
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rash
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What drugs produce adverse effects generally gastrointstinal in nature (#2)?
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meloxicam and indomethacin
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what are the adverse effects of celecoxib?
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similar to placebo - dyspepsia, diarrhea, abdominal pain
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what are the adverse effects of diclofenac?
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nausea, indigestion - typical of class
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what are the adverse effects of naproxen?
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shortness of breath, indigestion, tinnitus
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what would you tell a patient who is taking fentanyl?
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patches should be placed to non-irratated skin, not below knees or elbows. hair on site should be clipped and not shaven. do not use soaps to clear area prior to using.
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what would you tell a patient using lidocaine patches?
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do not use external heat sources such as electric blankets or heating pads over the lidoderm patch
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what would you tell a patient using celecoxib?
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promptly report any signs of ulcerations and bleeding (i.e, intense GI pain or dark stool) to a physician
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what would you tell a patient using oxycodone (CR) or morphine sulfate?
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tablet is not to be crushed, broken, or chewed - this may cause a rapid release of the drug and cause toxic effects
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What drugs may cause drowsiness and thus the patient should use caution when operating a motor vehicle or when mental alertness is required?
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suboxone, oxycodone (IR), methadone, percocet, tylenol, carisoprodol, vicodin, fioricet, tramadol, cyclobenzaprine
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what drugs should the patient be: "compliant for up to 2 weeks, because it may take up to 2 weeks to have noticeable improvement in arthritic conditions" (#4)?
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naproxen, indomethacin, meloxicam, ibuprofen
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what would you tell a patient on diclofenac sodium?
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concurrent ingestion of alcohol will increase ulcerogenic effects
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What drugs come in the form of capsules (#3)?
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celecoxib, cyclobenzaprine (or tab), and indomethacin (powder/supp)
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what dosage form is buprenorphine with naloxone?
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tablet or film: both SUBLINGUAL!
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what is the brand name of buprenorphine with naloxone?
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suboxone
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what is the brand name of indomethacin?
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indocin
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what is the brand name of cyclobenzaprine (#3)?
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amirix, flexeril, fexmid
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what are the other brand names for vicodin?
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lortab, lorcet, norco
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what is the brand name of carisoprodol?
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soma
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what is the brand name for oxycodone HCl (immediate release)?
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roxicodone
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what is the brand name of meloxicam
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mobic
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what is the brand name of diclofenac sodium?
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voltaren
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what is the brand name of morphine sulfate?
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MS Contin
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what is the brand name of Oxycodone HCl (controlled release)?
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Oxycontin
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what is the brand name of tramadol?
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ultram, ryzolt
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what is the brand name of butalbital with acetaminophen and caffeine?
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Fioricet, esgic-plus
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which drugs are in the class of "analgesics" (#2)?
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butalbital with acetaminophen and caffeine, and tramadol HCl
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which drugs are in the class "muscle relaxant" (#2)?
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cyclobenzaprine, carisoprodol
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what is the drug class of buprenorphine with naloxone?
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agent for opioid dependence
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What drugs have a contraindication of "hypersensative to NSAIDs" (#6)?
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All NSAIDS - naproxen, ibuprofen, meloxicam, indomethacin, celebrex, and dicofenac Na
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What drugs have a contraindication of "respiratory depression" (#3)?
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oxycodone (IR/CR), morphine
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what drugs have a contraindication of "hypersensative to any component of the drug" (#7)?
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fiorecet, suboxone, percocet, lidocaine, celecoxib, fentanyl, and tramadol
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What drug has should be used with caution in patients who are prone to hyperventilation?
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fentanyl
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what is methadone contraindicated for (dosage form)?
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injection
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what is cyclobenzaprine contraindicated for?
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congestive failure, hyperthyroidism
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what is carisoprodol contraindicated for?
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acute intermittent porphyria
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what drugs should you use with caution for "intracranial pressure" (#2)?
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anything with oxycodone or acetaminophen
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