Drug Information From Sigler 27Th Edition Drug Cards - Antihypertensive

Front 1

What drugs have an FDA indication for hypertension?

Back 1

olmesartan medoxomil, clonidine HCl, metoprolol succinate, enalapril maleate, lisinopril, atenolol, amlodipine besylate, carvedilol, valsartan, losartan potassium, metoprolol tartrate

Front 2

Brand name of metoprolol tartrate

Back 2

lopressor

Front 3

brand name of losartan potassium

Back 3

cozaar

Front 4

brand name of valsartan

Back 4

diovan

Front 5

brand name of carvedilol

Back 5

coreg

Front 6

brand name of amplodipine besylate

Back 6

norvasc

Front 7

brand name of atenolol

Back 7

tenormin

Front 8

brand name of lisinopril

Back 8

prinivil, zestril

Front 9

generic name for vasotec

Back 9

enalapril maleate

Front 10

brand name of metoprolol succinate

Back 10

toprol-XL

Front 11

generic name for catapres

Back 11

clonidine HCl

Front 12

brand name of olmesartan medoxomil

Back 12

benicar

Front 13

generic name for microzide

Back 13

hydrochlorothiazide

Front 14

brand name of isosorbide mononitrate

Back 14

imdur

Front 15

brand name of diltiazem HCl

Back 15

cardizem

Front 16

generic name for lasix

Back 16

furosemide

Front 17

generic name for dyazide

Back 17

triamterene with hydrochlorothiazide

Front 18

brand name of digoxin

Back 18

lanoxin

Front 19

brand name of verapamil HCl

Back 19

isoptin

Front 20

Which drugs fall under the class "diuretic"

Back 20

hydrochlorothiazide, furosemide, triamterene with hydrochlorothiazide

Front 21

What is the FDA indication for diuretics?

Back 21

adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, nephrotic syndrome, and in corticosteriod (and estrogen induced edema - dyazide only)

Front 22

what are the FDA indications for isosorbide mononitrate and diltiazem HCl?

Back 22

for prophylactic treatment of angina pectoris due to coronary disease

Front 23

what is the FDA indication of digoxin?

Back 23

treatment of heart failure, atrial fibrillation, atrial flutter and paroxysmal atrial tachycardia

Front 24

what is the FDA indication of verapamil HCl?

Back 24

treatment of vasospastic angina, unstable angina, and chronic stable angina.

Front 25

what is the pharmacology of diuretics?

Back 25

inhibit reabsorption of sodium and chloride in distal renal tubules.

Front 26

what is the pharmacology of olmesartan, valsartan, and losartan?

Back 26

selectively blocking the binding of angiotensin II to the AT1 receptor

Front 27

what is the pharmacology of metoprolol tartrate, metoprolol succinate,cardvedilol and atenolol?

Back 27

relatively cardioselective beta-1 adrenergic receptor blocker NOTE: carvedilol is an alpha blocker

Front 28

what is the pharmacology of diltiazem?

Back 28

calcium channel blocker, inhibits influx of calcium ions across specific cell membranes

Front 29

what is the pharmacology of isosorbide?

Back 29

relaxation of smooth muscle

Front 30

what is the pharmacology of digoxin?

Back 30

inhibits membrane bound Na/K ATPase (increased intracellular NA, and decreased K )

Front 31

what is the pharmacology of verapamil?

Back 31

calcium channel blocker

Front 32

what is the pharmacology of clonidine?

Back 32

stimulates central alpha-adrenergic receptors - inhibition of bulbar sympathetic cardioaccelerator and sympathetic vasoconstrictor centers

Front 33

what is the pharmacology of enalapril and lisinopril?

Back 33

active ingredient is enalaprilat - suppression of renin-angiotensin-aldosterone system. competitively inhibits angiotensin converting enzyme

Front 34

what is the pharmacology of amlodipine

Back 34

calcium channel blocker

Front 35

you should use enalapril with caution in patients who:

Back 35

are pregnant or nursing, impaired renal function, undergoing surgery

Front 36

you should use clonidine with caution in patients who:

Back 36

have severe coronary insufficiency, recent myocardial infarction, cerebrovascular disease

Front 37

what is a contraindication in amlodipine?

Back 37

may cause rare increase in risk of angina or myocardial infarction

Front 38

what is a contraindication for lisinopril

Back 38

history of angioedema, impaired renal function

Front 39

what is a contraindication for carvedilol

Back 39

patients with NYHA class IV decompensated cardiac failure, bronchial asthma

Front 40

what is a contraindication of verapamil?

Back 40

patients with severe left ventricular dysfunction, hypotension

Front 41

what is a contraindication for digoxin

Back 41

ventricular fibrillation, pregnancy, nursing

Front 42

what is a contraindication of isosorbide?

Back 42

patients hypersensative to nitrates, caution with myocardial infarction

Front 43

what is a contraindication of valsartan losartan and olmesartan?

Back 43

discontinued if pregnant, caution in volume or salt-depleted patients - from hypotension

Front 44

what is a contraindication of diltiazem?

Back 44

patients with sick sinus syndrome, AV block

Front 45

what drugs have a contraindication of "patients with anuria or hypersensitive to sulfonamides" (#3)

Back 45

dyazide, lasix, microzide (diuretics)

Front 46

what drugs have a contraindication of "sinus brachycardia, heart block greater than first degree" (#3)

Back 46

atenolol, metroprolol (tartrate/succinate)

Front 47

what drugs have a contraindication of "hypersensative to any component and drugs that act directly on renin-angiotensin system could cause fetal morbidity" (#2)

Back 47

olmesartan, losartan

Front 48

what is an adverse effect of clonidine?

Back 48

dry mouth, dry eyes

Front 49

what is a contraindication of losartan?

Back 49

upper respiratory infection

Front 50

what drugs have an adverse effect of headaches? (#3)

Back 50

valsartan, enalapril, isosorbide

Front 51

what drugs have an adverse effect of weakness and muscle cramps? (#3)

Back 51

dyazide, lasix, microzide

Front 52

what is the adverse effect of digoxin?

Back 52

anorexia, nausea, vomiting

Front 53

what drugs have an adverse effects of edema and flushing?

Back 53

amlodipine, diltiazem

Front 54

what are teh adverse effects of verapamil?

Back 54

hypotension, peripheral edema

Front 55

what would you tell a patient on carvedilol?

Back 55

take with food to decrease orthostatic hypotension, contact lens wearers may experience decreased lacramation

Front 56

what would you tell a patient on a diuretic?

Back 56

timing of dose is important because of increased diuresis. usually take in the morning

Front 57

On what drug would you tell a patient: "avoid non-prescription cough, cold, and allergy medications unless otherwise directed" (#5)

Back 57

amlodipine, enalapril, digoxin, lisinopril, clonidine

Front 58

On what drugs would a diabetic patient have to be aware of possibe masking of hypoglycemia?

Back 58

metoprolol (succinate, tartrate), atenolol, carvedilol

Front 59

on what drugs would you tell a patient: "take each dose on an empty stomach at least one hour before a meal or two hours after a meal" (#2)

Back 59

verapamil, diltiazem

Front 60

what would you tell a patient on isosorbide?

Back 60

may cause dizziness and flushing. headaches are a sign of drug effectiveness. do not adjust dosage to treat headaches - use aspirin or tylenol. dizziness is common when standing.