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10 Cards in this Set
- Front
- Back
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What information do you need from the patient to determine Glomerular Filtration Rate (GFR)?
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Physical exam - presence of ascites, edema, or dehydration.
Height Weight (Ideal vs actual BW) sex/age Serum Creatinine |
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What is the equation for cockroft-gault to measure Creatinine Clearance?
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(140-age) x Ideal Body Weight (Kg)/
72 x Serum Creatinine x.85 for women IDW (Men) = 50 + 2.3/ inches over 5ft IDW (Women) = 45.5 + 2.3/inches over 5ft |
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What is the MDRD equation?
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It is the Modification of Diet in Renal Disease
Takes race into account and may be more accurate for those with impaired renal function Not used in dosage adjustments |
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What are the 3 types of dialysis?
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Hemodialysis
Peritoneal Dialysis Continuous Renal Replacement Therapy (CRRT) |
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Changes in liver blood flow can be attributed to these two things.
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Acute blood loss
Cirrhosis |
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Decreased blood flow to the liver would decrease "first pass effect". This would have what 2 effects in terms of drug metabolism?
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Increased Bioavailability
Increased adverse effects and toxicity |
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Damage to hepatocytes would alter these two liver function tests.
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AST/ALT
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Cholestasis and decreased conjugation would alter this value
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Direct Bilirubin/Total Bilirubin
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Changes in synthetic function would alter these two values.
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Albumin
INR |
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What are the Beers Criteria?
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A guide of medications that are inappropriate for the elderly.
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