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37 Cards in this Set

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Penicillin G
IV 20-24 million U/day
IM 1.2 million U/day
DOC for most pure streptococcal infections
1 million U = 625mg
Penicillin V
250-500 mg PO q6h
Ampicillin
*IV 2g q4-6h
(PO 250-500 mg q6h)
Amoxicillin
PO 250-500 mg q8h
Better oral absorption than ampicillin
Nafcillin
IV or IM 1-2 g q4-6h
DOC Staph aureus
Cloxacillin
PO 250-500 mg q6h
Dicloxacillin
PO 250-500 mg q6h
Timentin
Ticarcillin/Clavulanic Acid
IV 3.1 g q6-8h (3 g ticaracillin + 100 mg Clavulanic acid)
Anaerobes/staph/strep
Watch for Na+ loading & hypokalemia
Augumentin
Amoxicillin/Clavulanic Acid
PO 500-875 mg (*all contain 125 mg Clavulanic acid)
DOC human/animal bites
Unasyn
Ampicillin/Sulbactam
IV/IM 1.5-3 g q6h
1.5 less severe inf.
Parenteral 2:1 - 2 g A to 1 g S
Acinetobacter (troops from Middle East)
USA
Zosyn
Piperacillin/Tazobactam
IV 3.375 g q6h
DOC DFI
Pseudomonas
"Take care of pseudomonas"
T = ticarcillin
C = carbenicillon
P = piperacillin
*Never as single use
Cephalexin
Keflex
1st generation
Gram +
PO 250-1000 mg q6-12h
Cefazolin
Ancef
IV 250-1500 mg q6-8h
1st generation
DOC surgical prophylaxis
B/C: 1. Staph/strep MC so cover them 2. Long 1/2 life 3. Excellent penetration
Cefuroxime
Ceftil
2nd generation - more Gram -
PO 250-500 mg q12h
Ceptriaxone
Rocephin
3rd generation
IV/IM 0.5-2 g q12h
DOC gonorrhea
*give IM in ass so you can jump start coverage until IV/PO kick in
Ceftazidime
Fortaz
IV/IM 1g q8-12h
Cefepime
Maxipime
4th generation
Anti-pseudomonal (others are better)
IV 1-2 g q12h
Ciprofloxacin
Cipro
Fluoroquinolones
PO 250-750 mg q12h
IV 200-400 mg q12h
DOC pseudomonas infection if it's the only thing grown on culture
SE: Increased risk of tendonopathy
Levofloxacin
Levaquin
Fluoroquinolone
PO/IV 250-750 mg q12h
***DOC: LE DFI***
SE: Increased risk of tendonopathy
Moxifloxacin
Avelox, Vigamox
Fluoroquinolone
PO 400 mg q24h
Empiric DFI
SE: Increased risk of tendonopathy
Imipenem
Primaxin = imipenem/cilastin
Carbapenems
IV 500 mg q6-8h
Broad spectrum - "gorillamycin"
Cilastin prevents hydrolysis in kidneys
Lowers seizure threshold
Meropenem
Merrem
Carbapenem
IV 1-2 g q8h
More Gram (-) coverage

Ertapenem
Invanz
Carbapenem
IV/IM 1g q24h
Once daily dosing*
DOC empiric tx DFI
NO pseudomonas coverage
Gentamicin
Aminoglycoside
IV 5-7 mg/kg q24h
Loading dose: 2 mg/kg
Gram (-)
Tobramycin
IV 5-7 mg/kg q24h
Loading dose: 2 mg/kg
Gram (-)
Amikacin
Aminoglycoside
IV 7.5 mg/kg q12h
Loading dose: 7.5 mg/kg
Gram (-)
Aminoglycoside SE
1. Ototoxicity
2. Nephrotoxicity
3. Neuromuscular blockade
Metronidazole
Flagyl
PO 500 mg q6-8h
DOC: Pseudomembranous colitis from c. diff
Gram (-) anaerobes
Clindamycin
Macrolide
IV 600-900 mg q8h
Outpt: PO 150-300 mg q8-24h
Metabolized by liver
Gram (+) & anaerobes, not MRSA
MCC OF DIARRHEA SECONDARY TO C. diff
Erythromycin
Macrolide
PO 250-500 mg q6h
DOC corynebacterium minutissimum (woods lamp)
SE: GI (N/V)
Azithromycin
Macrolide
Gram (+)
Z Pak: 500 mg (2 pills) day 1 --> 250 mg for 4 days
Minocycline
Tetracycline
PO 100 mg q12h
DOC: MRSA when TMP/SMX is resistant or linezolid is too $$
Contraindicated in pregnancy - teeth staining
Gram (+) & (-), and unusual pathogens
Doxycycline
Tetracycline
PO 100 mg q12h
DOC early Lyme disease at erythema migrans stage
Contraindicated in pregnancy
Gram (+) & (-), including MRSA
Vancomycib
IV 1g q12h (slowly over 45-60 min)
PO 125 mg q6h *only indicated for colitis d/t poor absorption
Max dose: 2g/d
***monitor troughs, normal is 10uL, if too high, must increase TIME between dosing
DOC: MRSA & MRSE
Linezolid
Zyvox
IV/PO 600 mg q12h
Covers all Gram (+)
DOC: very resistant Gram (+) infections
VERY $$$$
Rifampin
Rifadin
PO 300 mg q12h
Adverse: RED body fluids
Used in combo therapy - rapid development of resistance