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69 Cards in this Set

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Acetylcysteine (Tylenol OD) PO
Load 140 mg/kg, then 70 mg/kg q4h x 17 doses
Acetylcysteine (Tylenol OD) IV
Load: 150 mg/kg in 200 mL D5W infused over 15 mins
Maintenance: 50 mg/kg in 500 mL D5W infused over 4 hrs, followed by 100 mg/kg in 1000 mL D5W infused over 16 hrs
(PO preferred)
Acetylcysteine (Contrast PPx)
PO: 600 mg q12 x 4 before contrast
IV: 150 mg/kg in 500 mL NS over 30 mins before contrast followed by 50 mg/kg in 500 mL NS over 4 hours
Adenosine (AV node blockade)
6 mg IV push and flush within in 3 secs
repeat 12 mg after 1 min
repeat 12 mg again
Amiodarone (VF/VT)
300mg IV rapid infusion in 20-30 mL of NS or D5W
Amiodarone (Stable Arrhythmias)
Load: 150 mg in 100 mL D5W over 10 mins, then 900 mg in 500 mL D5W at 1 mg/min x 6 hrs (360 mg), then 0.5 mg/min x 18 hrs (540 mg)
Breakthrough events: Bolus 150 mg in 100 mL over 10 mins
Maintenance: 0.5 mg/min
Max Dose: 2.2g/day
Atropine (asystole or "slow" PEA)
1 mg IV q 3-5 mins for total of 3mg
OR
3mg down ETT diluted to 10 mL with NS
Atropine (bradycardia)
0.5-1 mg q 3-5 mins to max of 0.04 mg/kg
Atropine (anticholinesterase poisoning)
2-3 mg IV/IM q 20 mins until muscarinic symptoms resolve, max 6 mg/hr
Diphenhydramine (allergy)
50 mg IV/IM
Epinepherine (allergy)
0.3-0.5 mg IM (1:1000)
OR
0.1 mg IV (1:10,000)
repeat q 20 mins
Methylprednisolone (allergy)
125 mg IV/IM
Enalapril (hypertension)
1.25-5 mg IV over 5 mins (avoid in acute MI)
Esmolol (hypertension)
500 mcg/kg IV over 1 min then titrate 50-300 mcg/kg/min
Fenoldopam (hypertension)
0.1-0.3 mcg/kg/min titrate up to 1.6 mcg/kg/min
Labetalol (hypertension)
0.25 mg/kg IV may double dose q 10-15 mins PRN to total of 300 mg or 2 mg/kg - which ever is less
Nicardipine (hypertension)
start 2-4 mg/h IV, increase 1-2 mg/h q 15 mins to max of 15 mg/h
Nitroglycerin (hypertension)
Start 5-20 mcg/min IV; titrate up to 100 mcg/min
Sodium Nitroprusside (hypertension)
0.25-10 mcg/kg/min
Diltiazem (SVT)
bolus 0.25 mg/kg or 20 mg IV over 2 mins; may repeat 0.35 mg/kg or 25 mg IV 15 mins later
Infuse 5-15 mg/h (mix 250 mg (50mL) dilt with 250 mL fluid (0.833 mg/mL)
Epinepherine (cardiac arrest)
1 mg IV q 3mins (1:10,000)
2-2.5 mg in 10 mL NS down ETT
Lidocaine (dysrhythmia/cardiac arrest)
1 mg/kg IV then 0.5 mg q 5-10 mins prn to max of 3 mg/kg
Maintenance: 2 g in 250 mL D5W (8mg/mL) at 1-4 mg/min (7-30 ml/h)
Vasopressin (VF)
40 units IV x 1
Dobutamine
250 mg in 250 mL D5W (1mg/mL) at 2.5-20 mcg/kg/min
Dopamine
400 mg in 250 mL D5W (1600 mcg/mL) at 2-20 mcg/kg/min
2.5 mcg/kg/min: dopaminergic
5-10 mcg/kg/min: beta
>10 mcg/kg/min: alpha
Epinepherine
0.1-4 mcg/kg/min
Norepinepherine (Levophed)
4 mg in 500 mL D5W (8mcg/mL) at 0.5 - 10 mcg/min (max 30 mg/min)
Phenylepherine (Neo-synepherine)
100-500 mcg boluses IV
OR
20 mg in 250 mL D5W (80 mcg/mL), start at 100-180 mcg/min (75-135 ml/h)
Once BP stable, decrease to maintenance of 40-60 mcg/min
Etomidate (RSI)
0.3-0.4 mg/kg IV
Propofol (RSI)
2-2.5 mg/kg IV
Propofol (Ventilator Sedation)
5-50 mcg/kg/min
Rocuronium (RSI)
0.6-1.2 mg/kg IV
Succinylcholine (RSI)
1-1.5 mg/kg IV
Thiopental (RSI)
3-5 mg/kg IV
Fentanyl (RSI)
2-10 mcg/kg iV
Ketamine (RSI)
1-2 mg/kg IV
Midazolam (RSI)
0.1-0.3 mg/kg IV
Diazepam (seizures)
2-20 mg IV
OR
0.2-0.5 mg/kg PR up to 20 mg PR
Fosphenytoin (seizures)
15-20 mg/kg IM/IV max rate ≤150 mg/min
Phenytoin (seizures)
20 mg/kg up to 1000 mg IV no faster than 50 mg/min
Lorazepam (seizures)
0.1 mg/kg up to 3-4 mg IV/IM
Phenobarbital (seizures)
200-320 mg IV at 60 mg/min
status epilepticus: 20 mg/kg
Metoprolol (Acute MI)
5 mg IV q 5 mins x 3 doses; after 15 mins start 50 mg PO q 12hrs x 24hrs; then increase to 100 mg PO BID
Atenolol (Acute MI)
5 mg IV over 5 mins, rpt once after 10 mins if tolerated, follow by 50 mg PO BID or 100 mg PO daily
Propranolol (Acute MI)
0.1 mg/kg by slow IV push divided into 3 equal doses at 2-3 min intervals (max 1 mg/min). may rpt after 2 hours if necessary. Start 40 mg PO after 2 hrs, then 40 mg PO q 4hrs x 7 doses. Then start long term therapy at with 180-240 mg/d in divided doses
Bicarbonate (hyperkalemia or urgent intractable acidosis)
1 mEq/kg (1 amp = 50 mEq), then 0.5 mEq/kg q 10 mins as guided by blood gases
Bicarbonate (Urinary alkalinization)
2-5 mEq/kg IV over 4-8 hours
Calcium (hyperkalemia)
5-10mL of 10% IV CaCl2 (15-30 calcium gluc) over 1-5 mins
Calcium (tetany)
10 mL of 10% CaCl2 (30 mL gluconate) IV over 10 mins
Calcium (calcium antagonist toxicity)
10-20 mL of 10% CaCl2, infuse 0.5 mEq/kg/hr
Calcium (hypocalcemia)
10 mL of 10% CaCl2 (30 mL gluconate) in 500 mL NS over 6 hours
Chlorothiazide
500-1000 mg IV qd or bid. Ideally given 30 mins prior to loop diuretic
Clonidine (urgent HTN)
0.1-0.2 mg PO then 0.1 mg hourly; Max dose 0.8 mg
Clonidine (easing withdrawal symptoms)
0.3-0.6 mg PO q6hrs
Dantrolene (malignant hyperthermia) (?neuroleptic malignant syndrome)
1 mg/kg rapid IV. Repeat as rapidly as necessary until reversal of process (usually 2.5mg/kg) up to 10 mg/kg
Follow with 1-2 mg/kg PO qid x 3 days
Desmopressin (hemorrhage in uremia, hemophilia A and von Willebrand disease)
0.3 mcg/kg IM or IV (in 10-50 mL NS)
Desmopressin (central diabetes insipidus)
2 mcg IV qd - bid, titrate to urine output, serum sodium and osmolality
Digoxin Ab
IV: Loading dose (# of vials) = [serum dig level in ng/mL] x [weight in kg] / 100. (0.5 mg/vial. 0.5 mg will bind 0.5 mg of dig). Give IV over 30 mins or bolus through 22 micron filter

Empirical: 10-20 vials IV bolus for life threatening toxicity with no level
Furosemide (Diuresis)
Bolus: Starting - 20-40 mg IV, Max - 500 mg

Infusion: Loading - 40 mg IV, Rate - 10-20 mg/h (normal renal function); 20-40 mg/h (renal insufficiency)
Bumetanide (diuresis)
Bolus: Start - 0.5-1 mg IV, Max - 10 mg

Infusion: Loading - 1 mg, Rate - 0.5-1 mg/h (normal renal fxn); 1-2 mg/h (renal insufficiency)
Torsemide (diuresis)
Bolus: Start - 10-20 mg IV, Max - 200 mg

Infusion: Loading - 20 mg; Rate - 5-10 mg/h (normal renal fxn); 10-20 mg/h (renal insufficiency)
Drotrecogin Alfa (activated protein C or Xigris)
24 mcg/kg/hr IV infusion x 96 hrs
Flumazenil (benzo OD)
0.2 mg over 30 secs, increase to 0.3 mg over 30 secs if still lethargic then 0.5 mg over 30 secs q 1 min up to 3mg total
Fomepizole (ethylene glycol or methanol poisoning)
Load 15 mg /kg (in 100 mL of NS or D5W), then 10 mg/kg q 12 hrs x 4 doses, then 15 mg/kg q 12 hrs. Continue until pH normalizes and ethylene glycol or methanol levels < 20 mg/dL
Fondaparinux (pulmonary embolism)
5 mg qd sc (body weight < 50 kg)
7.5 mg qd sc (body weight 50-75 kg)
10 mg qd sc (body weight > 75 kg)
Glucagon (hypoglycemia)
1 mg IV/IM/SC, repeat q 15 mins 1-2 times
Glucagon (CCB or beta blocker toxicity)
5-10 mg bolus over 1 min then infusion at 1-10 mg/h
Glucagon (anaphylaxis unresponsive to epinephrine)
1-2 mg IV/IM q 5 mins
Fondaparinux (ACS)
2.5 mg SQ qd