Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/20

Click to flip

20 Cards in this Set

  • Front
  • Back
Name 12 immunosuppresants?
azathioprine
bailiximab
chlorambucil
cyclophosphamide
cyclosporine
daclizumab
methotrexate
muromonab-CD3
mycophenolate
sirolimus
tacrolimus
thalidomide
Azathioprine, basiliximab, cyclosporine, daclizumab, mycophenolate, sirolimus, and tacrolimus are used with _____ in the prevention of transplantation rejection reactions.
corticosteroids
Which agent is used to manage rejection reactions not controlled by other agents?
Muromonab-CD3
Which 3 agents are used in the management of selected autoimmune diseases (nephrotic syndrome of childhood and severe rheumatoid arthritis).
azathioprine
cyclophosphamide
methotrexate
Immunosuppressants inhibit ____-_____ immune responses by different mechanisms.
cell-mediated
In addition to azathioprine and cyclosporine, which are used primarily for their immunomodulating properties, cyclophosphamide and methotrexate are used to suppress the ______ _______ in certain disease states (nephrotic syndrome of childhood and severe rheumatoid arthritis).
immune responses
Muromonab-CD3 is a recombinant _______ antibody that alters T-cell function.
immunoglobulin
Basiliximab and daclizumab are ______ antibodies.
monoclonal
Contraindications?
hypersensitivity to drug or vehicle
Precautions?
use cautiously in patients with infections...
safety in pregnancy and lactation not established
Allopurinol inhibits the _____ of azathioprine.
metabolism
Drugs that alter liver-metabolizing processes may change the effect of ______.
cyclosporine
The risk to toxicity of ______ may be increased by other nephrotoxic drugs, large doses of aspirin, or NSAIDs.
methotrexate
________ has additive immunosuppressive properties; concurrent immunosuppressive doses should be decreased or eliminated.
Muromonab-CD3
What should the nurse assess for when patient is taking immunosuppressants?
infection (VS, sputum, urine, stool, WBCs); notify hcp immediately if symptoms occur...
organ rejection...
CBC
differential
List 2 potential nursing diagnoses?
Infection, risk for....
Knowledge, deficient, related to disease processes and medication regimen
IMPLEMENTATION:
Protect _______ patients from staff and visitors who may carry infection.
Maintain protective isolation
as indicated.
transplant
Reinforce the need for lifelong therapy to prevent 1______ _____. Review symptoms of 2_______ for transplanted organ and stress need to notify hcp immediately if they occur.
1 transplant rejection
2 rejection
Advise patient to avoid contact with _____ persons and those who have recently taken oral ____ virus vaccine. Patients should not receive vaccinations without first consulting with hcp. Emphasize the importance of follow-up exams and lab tests.
contagious
polio
EVALUATION:
Effectiveness of therapy can be demonstrated by?
Prevention or reversal of rejection of ___ ____ or decrease in symptoms of autoimmune disorders.
organ transplants