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28 Cards in this Set

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Name 3 anticholinergics?
benztropine {Apo-Benztropine}, Cogentin

biperiden Akineton

trihexyphenidyl Artane
Name 1 antiviral?
amantadine
Symmetrel
Name 2 catechol-O-methyltransferase inhibitors?
entacapone Comtan
tolcapone Tasmar
Name 6 dopamine agonists?
bromocriptine
Parlodel

carbidopa/levodopa
Sinemet, Sinemet CR

levodopa
Dopar, Larodopa, L-dopa

pergolide
Permax

pramipexole
Mirapex

ropinirole Requip
Name 1 monoamine oxidase type B inhibitors?
selegiline Apo-Selegiline, Carbex, Eldepryl, Gen-Selegiline, Nu-Selegiline, {Novo-Selegiline}, SD-Deprenyl
Name 5 groups of antiparkinson agents?
anticholinergics
antiviral
catechol-O-methyltransferase
inhibitors
dopamine agonists
monoamine oxidase type B inhibitors
.
.
Antiparkinson agents are used in the treatment of parkinsonism of various causes? (5)
degenerative
toxic
infective
neoplastic
drug-induced
What 2 neurotransmitters are antiparkinson agents trying to restore?
acetylcholine
dopamine
The imbalance is a deficiency in _____ that results in excessive cholinergic activity.
dopamine
______ inhibits the enzyme that breaks down levodopa, thereby enhancing its effects.
Levodopa
Anticholinergics should be avoided in patients with ____-____ glaucoma.
narrow angle
Use antiparkinson agents cautiously in patients with severe? (3)
cardiac disease
pyloric obstruction
prostatic enlargement
Which six antiparkinson agents may antagonize the effects of levodopa?
pyridoxine
MAO inhibitors
benzodiazepines
phenytoin
phenothiazines
haloperidol
Agents that antagonize dopamine (_____, _____) may decrease effectiveness of dopamine agonists.
phenothiazines
metoclopramide
Assess these parkinsonian and extrapyramidal symptoms (9) before and throughout course of therapy. On-off phenomenon may cause symptoms to appear or improve suddenly.
akinesia
rigidity
tremors
pill rolling
mask facies
shuffling gait
muscle spasms
twisting motions
drooling
Monitor blood pressure frequently during therapy. Instruct patient to remain ____ during and for several hours after first dose of _____, as severe hypotension may occur.
supine
bromocriptine
3 Potential Nursing Diagnoses?
Mobility, impaired physical
Injury, risk for
Knowledge, deficient, related
to disease processes and
medication regimen
In the carbidopa/levodopa combination, the number following the drug name represents the ______ of each respective drug.
milligram
Antiparkinson agents may cause _____ or _____. Advise patient to avoid driving or other activities that require alertness until response to medication is known.
drowsiness
dizziness
Caution patient to make position changes slowly to minimize?
orthostatic hypotension
Which three measures may patient use to decrease dry mouth?
Patient should notify hcp if dryness persists (saliva substitutes may be used). Also notify the dentist if dryness interferes with use of dentures.
frequent mouth rinsing
good oral hygiene
sugarless gum or candy
Advise patient to confer with hcp before ____ meds, especially cold remedies, or drinking alcoholic beverages.
OTC
Patients receiving levodopa should avoid ______?
Which vitamin may interfere with levodopa's action?
multivitamins

vitamin B6 (pyridoxine)
Advise patient to stay in air conditioning during hot weather as decreased _____ may occur.
perspiration
Advise patient to increase _____, _____, and ____ in diet to minimize constipating effects of medication.
activity
bulk
fluid
Advise patient to notify hcp if these 6 parkinsonian symptoms occur?
confusion
rash
urinary retention
severe constipation
visual changes
worsening of parkinsonian
symptoms
The effectiveness of therapy can be demonstrated by? (2)
resolution of parkinsonian
signs and symptoms
resolution of drug-induced
extrapyramidal symptoms