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14 Cards in this Set

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What are anti-Alzheimer agents used for?
management of Alzheimer's dementia
How do anti-Alzheimer agents work?
act by increasing the amount of acetylcholine in the CNS by inhibiting cholinesterase;
no agents to date can slow the progression of Alzheimer's dementia. Current agetns may temporarily improve cognitive function and therefore improve quality of life
Which anit-Alzheimer agent should not be used in patients who have had previous hepatic reactions to the drug?
Tacrine
Why should antialzheimer meds be used cautiously in patients with a history of "sick sinus syndrome" or other supraventricular cardiac conduction abnormalities?
may cause bradycardia
Cholinergic effects may result in adverse GI effects and may also increase gastric acid secretion which results in?
GI bleeding
(especially in concurrent use with NSAID therapy)
Adverse GI effects associated with antialzheimer drugs include the following symptoms?
Hint: There are 4 primary symptoms and 3 other cholinergic effects.
4 primary:
diarrhea
nausea
vomiting
weight loss

3 other:
urinary tract obstruction
seizures
bronchospasm
Antialzheimer drugs may exaggerate the effects of what type of muscle relaxation during anesthesia meds?
succinylcholine-type
Do antialzheimer drugs increase or decrease the therapeutic effects of anticholinergic meds?
decrease
What aspects of cognitive function should be assessed throughout antialzheimer therapy?
ability to perform simple
tasks
attention
language
memory
reasoning
What side effects should be monitored while on antialzheimers?
anorexia
nausea
vomiting
weight loss
What are 3 potential nursing diagnoses?
Thought processes; altered
Nutrition, altered: less
than body requirements
Knowledge deficit, related
to medication regimen
What are two patient/family teaching tips?
Take meds as directed
Notify hcp if anorexia,
nausea, vomiting, or
weight loss occurs
Clinical response due to the use of antialzheimer drugs will include?
temporary improvement in
cognitive function in
patient's with Alzheimers
disease.
The aspects of cognitive
function that will be
improved include:
ability to perform simple
tasks
attention
language
memory
Four antialzheimer drugs are?
donepezil Aricept

galantamine Reminyl

rivastigmine Exelon

tacrine Cognex