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69 Cards in this Set
- Front
- Back
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Acetylcholine
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Agonist of muscarinic and nicotinic receptors
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Methacholine
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Agonist of muscarinic receptors
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Carbachol
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Agonist of muscarinic receptors (some nicotinic effect)
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Bethanechol
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Agonist of muscarinic receptors
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Pilocarpine
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Muscarinic agonist
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Muscarine
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Muscarinic agonist
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Nicotine
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Initially activates ganglionic nACh receptors
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Edrophonium
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Simple competitive inhibitor of AChE
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Physostigmine
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Competitive substrate of AChE
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Neostigmine
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Competitive substrate of AChE
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Pyridostigmine
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Competitive substrate of AChE
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Echothiophate
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Inactivate active AChE site by covalent attachment (bind to serine site)
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Malathion
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Inactivate active AChE site by covalent attachment (bind to serine site)
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Parathion
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Inactivate active AChE site by covalent attachment (bind to serine site)
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Sarin/Soman
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Inactivate active AChE site by covalent attachment (bind to serine site)
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Atropine
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Muscarinic antagonist
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Scopolamine
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Muscarinc antagonist
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Tropicamide, Cyclopentolate, Homotropine
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Muscarinic antagonist
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Ipratropium, tiotropium
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Muscarinic antagonist
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Tolterodine
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Muscarinic antagonist (Bladder)
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Dicyclomine
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Muscarinic antagonist (GI)
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Glycopyrrolate
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Muscarinic antagonist
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Benzotropine
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Muscarinic antagonist
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Hexamethonium (C6)
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Ganglionic Nicotinic antagonist
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Mecamylamine
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Ganglionic Nicotinic antagonist
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Norepinephrine
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Alpha agonist (does not activate beta-2)
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Dopamine
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Renal Vasodilation (D1), Inhibition of NE Release (D2), Cardiac Stimulation (beta-1), Increased BP (alpha)
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Epinephrine
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Beta-agonist (low), alpha and beta (moderate), alpha agonist (high)
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Isoproterenol
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beta-agonist
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Dobutamine
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beta-agonist (primarily beta-1)
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Albuterol, metaproterenol
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beta-2 agonist
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Terbutaline, ritodrine
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beta-2 agonist
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Salmeterol
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beta-2 agonist
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Phenylephrine
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alpha-1 agonist
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Methoxamine
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alpha-1 agonist
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Clonidine
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alpha-2 agonist
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Methyldopa
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alpha-2 agonist
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Ephedrine, Pseudoephedrine
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NE agonist (periphery and CNS)
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Amphetamine
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Reverses NE transporter
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Cocaine
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Blocks NE reuptake, blocks DA reuptake (CNS)
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Tyramine
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NE agonist (release)
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Phenoxybenzamine
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Non-selective, irreversible alpha blocker
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Phentolamine
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non-selective alpha blocker
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Prazosin
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selective alpha-1 blocker
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Doxazosin, terazosin
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selective alpha-1 blocker
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Tamsulosin
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selective alpha-1A/D blocker
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Yohimbine
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selective alpha-2 blocker
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Propranolol
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non-selective beta blocker
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Timolol
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non-selective beta blocker
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Nadolol
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non-selective beta blocker
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Atenolol, metoprolol
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beta-1 blocker
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Esmolol
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beta-1 blocker
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Betaxolol
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beta-1 blocker
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Labetalol
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beta blocker, alpha-1 blocker
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Carvedilol
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beta blocker, alpha blocker
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Pindolol
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non-selective beta blocker
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Acebutolol
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beta-1 blocker
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Aliskiren
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inhibits renin
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Captopril (Class I)
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inhibit ACE, reduce breakdown of bradykinin
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Enalopril (Class II)
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inhibit ACE, reduce breakdown of bradykinin
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Lisinopril (Class III)
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inhibit ACE, reduce breakdown of bradykinin
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Losartan
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AT1 receptor antagonist
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Valsartan
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AT1 receptor antagonist
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Spironolactone, eplerenone
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aldosterone antagonist in cortical collecting tubule and late distal tubule
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HCTZ
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inhibit NaCl absorption in DCT
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Furosemide, bumetanide
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inhibit NKCC2 in ascending loop
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amiloride, triamterence
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inhibit ENaC channel in CD
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Conivaptan
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inhibit V1 and V2 receptors (decrease AQ2 synthesis)
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Tolvaptan
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oral V2 antagonist
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