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17 Cards in this Set

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Atropine Sulfate Class

Anticholinergic agent, Antidote, Antispasmodic agent, Antimuscarinic.

Atropine Sulfate M.O.A.

CV: Increased heart rate; increased conduction velocity; increased force of contraction; increased cardiac output.


Resp: Decreased mucus production; increased bronchial smooth muscle relaxation (bronchodilation)


GI: Decreased GI secretion and motility


GU: Decreased urinary bladder tone


Misc: Mydriasis (pupillary dilation); decreased sweat production

Atropine Sulfate Indications

- Symptomatic bradycardia


- Acetylcholinesterase inhibitor poisoning (organophosphate, carbamate cholinergic poisoning)

Atropine Sulfate Adult Dose

- Symptomatic Bradycardia : IV/IO -- 0.5mg every 5 minutes. Max total dose of 3mg.


- Organophosphate or carbamate poisoning :


--- IV/IO - 1-5mg. Dose should be doubled every 5 min until signs of muscarinic excess abate


--- IV infusion - 0.5-1mg/hr

Atropine Sulfate Bonus Answers

Onset: 1 min


Peak: IV-- 2-5min


IM-- 30min


Duration: 1/2 life --2-3 hours


Drug Box: 3 (1mg/10ml) prefilled syringes


Optional-- 1(8mg/20ml) multidose vial

Atropine Sulfate Special Notes

-Administering too small doses or too slowly may result in paradoxical bradycardia


-Signs and symptoms of cholinergic/organophosphate poisoning: excess salivation, lacrimation, urination, defecation, bradycardia, coma


-Patients that describe their glaucoma as painful probably have acute narrow angle glaucoma

Dopamine Class

Sympathomimetic

Dopamine M.O.A.

-1-2mcg/kg/min - Cerebral, renal, and mesenteric vasodilation


-2-10mcg/kg/min - Beta 1 stimulation is primary effect


-10-20mcg/kg/min - alpha stimulation is primary effect --(renal, mesenteric, peripheral arterial and venous vasoconstriction (increased SVR), increased pulmonary vascular resistance, and increased preload)


- >20mcg/kg/min - hemodynamic effects similar to norepinephrine; May increase HR and O2 demand to undesirable limits.

Dopamine Indications

-Symptomatic bradycardia


-Non-hypovolemic hypotension/shock (cardiogenic or septic shock AFTER fluid administration; assess breath sounds first)

Dopamine Adult Dose

Preparation: (if premixed not carried) Add 400mg to 250ml NS or D5W = 1600mcg/ml


Bradycardia: Start at 5mcg/kg/min IV infusion


Shock: Cardiogenic or Septic (non-hypovolemic)


-- BP < 70 systolic: Start at 5mcg/kg/min IV infusion


-- BP >70 systolic: Start at 2.5mcg/kg/min IV infusion

Dopamine Bonus Answers

Onset: Almost immediate


Peak: 5-10 min


Duration: Effects cease almost immediately when infusion is shut off


Drug Box: 400mg

Dopamine Special Notes

-Always monitor drip rate, never run "wide open"


-An infusion pump is required for interfacility transports

Phenylephrine Nasal Spray 0.5% (Neo-synephrine) Class

Topical vasoconstrictor

Phenylephrine Nasal Spray 0.5% (Neo-synephrine) M.O.A.

-Stimulates alpha receptors in the blood vessels of the nasal mucosa

Phenylephrine Nasal Spray 0.5% (Neo-synephrine) Indications

-Facilitation of nasotracheal intubation

Phenylephrine Nasal Spray 0.5% (Neo-synephrine) Adult Dose

-2-4 sprays in each nostril before attempting tube insertion

Phenylephrine Nasal Spray 0.5% (Neo-synephrine) Bonus Answers

Onset: Seconds


Peak: 30 min


Duration: 30 min - 4 hours


Drug box: Optional 1 bottle