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13 Cards in this Set
- Front
- Back
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episodic memory
structures involved? type of memory? examples? |
Med. temp., ant. thalamic n., mamillary bodies
explicit last birthday, recent story, dinnner last night |
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semantic memory
structures involved? type of memory? examples? |
inf. lat. temporal lobe
explicit facts: 1st prez, color of a lion, diff between comb and rake. |
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procedural memory
structures involved? type of memory? examples? |
basal ganglia
explicit : driving a stick-shift and implicit:learning phone number by repeated dialing (no cognition) |
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working memory (2 types)
structures involved? type of memory? examples? |
both use explicit
phonlogical : prefrontal , brocas hear+ remember a phone number in head spatial: prefrontal, vis. assoc. rotate objects in head |
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explicit memories?
implicit memories? |
explicit: facts and events
implicit: skills, rituals, classic conditioning |
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clinical features of delerium?
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acute
fluctuating confusion disturbed sleep/wake always medical prob. or drugs/ETOH, anti-cholinergics |
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Know the difference between delirium, pseudodementia and depression.
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Delerium: illness, loss of attention and consciousness speech prob.
psudodementia; elderly, sad mimics dementia Demetia: insidious, good attention, conscious, speech good |
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Understand the memory impairment and cognitive disturbances of dementia
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learn slower, distractable, store less
aphasia, apraxia, agnosia |
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Understand the relationship of APOE and risk for AD
(E4 vs E2) |
E4 increased risk, earlier onset
E2 protective effect. |
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the role of acetylcholine in AD--and be able to differentiate AD from vascular dementia,
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ach transferase nost common flaw in alz. treat w/ achE inhibitors
vascular d. is abrupt not insidious, fluctuating not persitent also has emotional incontinence and stairstep functionality |
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differentiate dementia due to alcohol and HIV dementia as far as the clinical features for each type.
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HIV has triad of motor, cognitive, and behavioral symptoms possible acute psychosis rapidy progresses to death in 6 mos.
alcohol primarily speech and ataxia prob. slowly progresses global loss of cognitive ability partially reversable |
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name some achE inhibitors
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tacrine, donezapil, razadyne, exelon
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drugs other than ache's to treat alzheimers?
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memantine (NMDA antagonist)
blocks glutamate receptor |
