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30 Cards in this Set
- Front
- Back
What are the classification of toxins?
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LT- heat labile
ST- heat stable F- fimbrial O- capsular K- Flagellar P- Pillus |
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What is the etiology of edema dz?
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E. coli (O- capsular)
stress at weaning endotoxins gut edema, bowl edema, pig Staggers |
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How is edema dz trasmitted?
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oral, slow spread
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What are the predispositioin for edema dz?
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1. weaning- diet adjustmant (put on high concentrate diets)
2. immature digestive tract 3. cold temps (must be kept at 65F) 4. delayed enzyme development (causes a bulid up of undigested starches for bac to feed on) |
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What are the environmental condition leading to edema dz?
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1. heavy feeding against high consentrates
2. recent transport 3. alter portion levels (protiens drop as animal get older) 4. change in antibiotics ( change the gut flora) 5. recent vax |
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What are the 2 pathogenesis of edema dz?
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anaphylactic shock due to the lipopolysaccharides of the E. coli.
Endotoxic shock bc the toxins increase vascular permeability causing edema |
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What are the clinical signs of edema dz?
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CNS signs, eyelid edema, sudden onset, short duration leading to recovery or death
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what are the lesions of edema dz?
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edema of the stomach, CNS, and other organs
Myocardial degeneration congestion of the small intestines kidney engorgement (pathognomoic) |
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What are the differentials for edema dz?
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pseudorabies
salt poisoning- due to water deprivation |
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What is the treatment for edema dz?
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Use teracycline
pigs should drink 2x as much water as food reduce feed around weaning change back to original antibiotic |
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What is the etiology of colibacillosis?
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E-coli type K 88, K99, 98P, F 18
seen in neonates Baby pig scours |
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How in colibacillosis transmitted?
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oral, umbilical cord
rapid spread 1 tbs of feces contains billion organisms and only takes 100o to cause death |
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What are the environment conditions that lead to colibacilosis?
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large furrowing houses with close pena and travels thru drafts
seen in pigs solely raised inside |
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What are the clinical signs of colibacillosis?
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pasty yellow diarrhea that stain perineum
dehydration, weight loss, lethargy |
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What lesions are seen in colibacilosis?
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congestion of the small intestines
diarrhea and gas die with food in the stomach |
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How do you diagnose colibacillosis?
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culture
high number of pathogens in anterior part of small intestines truck side test pH of colon= alk>bac and acid> virus |
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What is the truck side test?
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pea size drop of feces in tube add reagent and watch for color change
blue= bac orange= virus |
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What is the treatment for colibacillosis?
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early treatment of whole litter
tetracycline neomycin |
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What are the types of vaccines for colibacillosis?
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autogenous milk vaccine= isolate the antigen and inoculate in milk fed back to sows, this gives immunity to to piglets
Porcimune= hyperimmune antibodies, take an inactivated antibody and add it to milk, dose pigs orally Porcine ecolizer ( passive immunity)= vax sows at 5 weeks before forrowing to build up Imunoglobulin |
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What are the managment practices for colibacillosis?
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vax, sanitation, 50-70% humidity at 90F, prompt frequent suckling
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What is the etiology of TGE?
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Corona virus (sensitive to light)
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How is TGE transmitted?
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direct and indrect contact
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What a are the clinical Signs of TGE?
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vomit, diarrhea, hypothermia, agalactia, inappetance
dehydration, stunted growthshort incubation |
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What is the pathogenesis of TGE?
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columnar epi lost in the jejunum mainly, shorten villi, lack of absorption leads to dehydration and metabolic acidosis
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What are the lesions of TGE?
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villus atrophy
curds of undigested milk in stomach due to lactase enzyme thin transparent intestinal walls kidney degeneration(urates, cast) |
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What is the epizootic (acute form) of TGE?
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non- immune animals, rapid sread, V/D, run course in 2 wks
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What is the enzootic (chronic form)?
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presistant infection
sows are immune- provide passive immunity expose all animals with low levels instill imunity |
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How do you diagnose TGE?
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FA test, SN test, ELISA, PCR and CF test
tissues collected are tonsils, LN, and intestines |
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What is the treatment for TGE?
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Antibiotics, vitamins and electrolytes
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What are the vax available for TGE?
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Commercial- Diamond
Autogenous - feed back method to sows |