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54 Cards in this Set
- Front
- Back
What are the functions of blood
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Distribution, Regulation and Protection
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What is the pH of blood
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7.35-7.45
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What does Hematocrit mean?
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blood fraction
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What are the 2 parts of blood?
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Plasma (55%) and a complex of living cell called formed elements which make up the rest
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What are the 2 parts of blood?
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Plasma (55%) and a complex of living cell called formed elements which make up the rest
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What are the coomponents of blood plasma?
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8% protein-plasma volume
60% Albumin-maintain water presssure between blood and tissue 36%-Globulins-plasma proteins |
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What do alpha and beta proteins do?
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transport proteins that bind to lipids, metal ions and fat soluble vitamins
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What are Gamma proteins?
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antibodies released by plasma cells during immune response
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What is the formation of Red blood cells called?
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Erythropoieses
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Where does Erythropoises occour?
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in the red bone marrow found in the axial skeleton and epiphysis of long bones
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Where does Hemoglobin accumulation begin? What does it do?
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At early erythroblast and the increast accumulation(34%) eventually forces organelles out the cell and degratation and pinching off of the nucleus
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What do reticulocytes represent and what is it an indicator of?
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1-2% of all erythrocytes and is an indicator of the rate of red blood cell formation.
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What is formation or RBC regulated by?
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Erythropoiten(EPO)- produced by the kidneys
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Erythropoiten causes what?
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Regulation of O2 transport and production of RBCs
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What lies in between the layer of plasma and erythrocytes?
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The buffy coat
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What is the buffy coat?
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1% of blood that contains leukocytes and platelets.
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What do Leukocytes aka WBCs do?
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Help with the body's defense and immune system (4,000-11,000 cells)
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What do Leukocytes aka WBCs do?
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Help with the body's defense and immune system (4,000-11,000 cells)
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What are Basophils?
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the rarest of the WBCs that represent 0.5 to 1% of the leukocytes in the bloodstream; contain histamine filled granules that act as a vasodilator and an attractant for other WBCs that bind to immoglubin E which releases histamine
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What are Granulocytes?
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Phagocytic cells with lobed nuclei which tend to be large and short lived and stain with Wright's stain.
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What are Eosinophils?
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important for the body's response to parasitic worms and reduce the severity of allergies. they contain a 2 lobe nuclei and granules that stain deep red with an acid dye
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What are Neutrophils?
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Themost numerous of the WBC (50-70%) they attack bacteria and fungi and stain a liliac color. They have 3-6 lobule nuclei and very fine granules that contain definsins and hyrdolytic enzymes
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What are Agranulocytes?
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WBCs which lack visible cytoplasmic granules. Contain spherical or kidney shaped nuclei.
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What are Lymphocytes?
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25% of the WBC population. contain a large nulcei which takes up most of its space; play a crucial role in immunity
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What are T-Lymphocytes?
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act directly against virus infected and tumor forming cells
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What are B-lymphocytes?
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give rise to plasma cells which produce antibodies that are released in the blood
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What are Monocytes?
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the body's active phagocytic cells and account for 3 to 8% of the WBCs help in defense against viruses, bacterial parasites, and chronic infections.
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Platelets are fragments of a larger cell called a..?
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Megakaryocyte
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How do platelets help the body?
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Blood Clotting
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Platelets have granules which contain one or a mixture of....?
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Serotonin,calcium ions, enzymes, ADP, and platelet derived growth factor (PDGF)
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How long to platelets stay in the blood?
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10 days
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How are platelets kept inactive?
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NO2 and prostaglandin I2
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Platelet formation is regulated by?
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Thrombopoiten
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What is Anemia?
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a decrease in either RBC number or the ability to the RBC to retain O2
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What is a Hemorragic Anemia?
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low levels caused by blood loss
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What is Chronic Anemia
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slow continuous bleeding over time (bleeding ulcer)
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What is Acute Anemia?
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brief incident causing blood loss.
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What is a Hemolytic Anemia?
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erythrocytes rupturing or lysing prematurely- (holding in urine)
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What is an Aplastic anemia
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destruction or inhibitation or red marrow by certain bacterial toxins drugs or radiation
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What is the condition when your blood cells increase by moving to a high/low altitude?
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Polycythemia
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What is iron deficient anemia
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caused by inadequate intake of iron containing foods resulting in microcytes.
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What is Athletes anemia?
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occours after vigorous workout where the blood volume increase as much as 15%
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What is pernicious anemia?
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Vitamin B12 deficiency; large pale macrocytes are formed as a result
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What is Thalassemia?
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One of the hemoglobin chains are absent or faulty resulting in thin delicate erythrocytes.
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What is sickle cell anemia?
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a hereditary disorder that causes the abnormal formation of the beta hemoglobin causing the blood to take on a sickle like shape due to low O2 conditions
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What is blood doping?
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the practice of removing the blood for later infusion to provide a temporary state of polycythemia to increase performance
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What might Leukocytosis or high WBC inicate?
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viral or bacterial infection, metabolic disease, hemmhorage or poisoning
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What might Leukopenia or low WBC indicate?
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typhoid fever,measles, infectious hepatitis, or cirrhosis, tuberculosis, excessive antibodies or Xray therapy
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Polycythemia or High RBC may indicate..?
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bone marrow cancer, or the need to have more O2 carrying blood cells (high altitudes)
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What might low RBC or anemia indicate?
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Decrease in RBC number or the ability for the RBC to retain O2
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What is a highly contagious viral disease most often seen in children and young adults caused by the Epstein-Barr virus associated with a low grade fever, being tired, and a chronic sore throat?
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Infectious Mononucleosis
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A clot that forms in an umbroken blood vessel is called?
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Thrombus
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What is a thrombus that floats freely in the blood vessels called?
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Embolus
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When a Rh negative has a Rh positive child and becomes exposed to the mothers blood the mother will make antibodies targeting the next Rh positive child.
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Hemolytic Disease of the newborn
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