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16 Cards in this Set
- Front
- Back
Vasospastic Angina
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vasospasm of coranary arteries
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Vasospatic angina drugs
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nitrates and CCB (both)
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B-Blocker clinical use
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Post MI, Stable angina, prevent stroke, HTN
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First line therapy for stable angina
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B-blocker
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B-blocker contraindications
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Asthma, unstable heart failure, pheocromocytoma, av block, pulmonary edma
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Nitrates clinical use
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Both stable and vasospastic angina
Both acutely and prophylacticly |
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Nitrates MOA
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Stable (decreases O2 demand via decrease in PVR)
Vasospastic (increases O2 supply via dilation of coranary arteries) |
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Nitrate Side effects
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headache, flushing, orthostatic hypotension, dizziness, reflex tachycardia
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Nitroglycerin + B-blocker
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prevent reflex tachy
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DHP CCB
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decreases afterload, get reflex tachy
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Non-DHP CCB
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Decreases afterload, HR, Contractility and ultimiatley O2 demand
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CCB
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Dilate epicardial coronary arteries, increases O2 supply
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Ranolazine
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Decrease late Na influx which decreases Ca overload, no effect on HR or BP, for stable angina
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Ranolazine side effect
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dizziness, headache, constipation, nausea, Prolongs QT (causes bad arythmias)
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Prophylatic ischemic drugs
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B-blocker, CCB (both), Nitrates (both), Ranolazine
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Actue ischemic drugs
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Nitrates (both)
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