Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
30 Cards in this Set
- Front
- Back
|
Cyclophosphamide
ADR |
Alkylating Agent - Nitrogen mustard
-Can cause bladder toxicity |
|
|
MESNA
|
Binds Acrolein, given to reduce bladder toxicity against cyclophosphamide
|
|
|
Cisplatin
ADR |
Alkylating Agent - Platinum compound
-Significant N and V, renal toxicity |
|
|
Carboplatin
ADR |
Alkylating Agent - Platinum compound
-Thrombocytopenia |
|
|
Oxaliplatin
ADR |
Alkylating Agent - Platinum compound
-Cold exacerbates neuropathy |
|
|
Dacarbazine
|
Alkylating Agent - Other
|
|
|
Fluorouracil (5-FU)
Action |
Antimetabolite - Pyrimidine Analogues
-Inhibits Thymidylate synthase to block DNA synthesis |
|
|
Methotrexate
Action |
Antimetabolite - Antifolates
-Inhibits Dihydrofolate reductase to block DNA synthesis |
|
|
Paclitaxel
|
Antimicrotubule Agents - Taxane
|
|
|
Docetaxal
|
Antimicrotubule Agents - Taxane
|
|
|
Vincristine
ADR |
Antimicrotubule Agents - Vina Alkaloids
-Causes neurotoxicity |
|
|
Vinblastine
ADR |
Antimicrotubule Agents - Vinca Alkaloids
-Causes myelosuppression |
|
|
Ixabepilone
ADR |
Antimicrotubule Agents - Epothilones
-Causes myelosuppression and hepatotoxicity |
|
|
Etoposide
|
Topoisomerase II Inhibitor
-Also DNA intercalating agent |
|
|
Irinotecan
|
Topoisomerase I Inhibitors
|
|
|
Daunorubicin
|
DNA Intercalating Agents - Anthracyclines
|
|
|
Doxorubicin
|
DNA Intercalating Agents - Anthracyclines
|
|
|
Mitoxantrone
|
DNA Intercalating Agents - Anthracycline derivative
|
|
|
Bleomycin
|
DNA Intercalating Agents - Other
|
|
|
Tamoxifen
|
Hormonal Agents - Anti-Estrogenic Drugs
-Estrogen Receptor Antagonist |
|
|
Raloxifene
|
Hormonal Agents - Anti-Estrogenic Drugs
-Estrogen Receptor Antagonist |
|
|
Letrozole
|
Hormonal Agents - Anti-Estrogenic Drugs
-Aromatase Inhibitor |
|
|
Leuprolide
|
Hormonal Agents - Anti-Androgenic Drugs
-LHRH Agonist |
|
|
Imatinib
Target |
Targeted Therapy - Traditional small molecules
-Receptor Tyrosine Kinase Inhibitor -Target: BCR-abl (Ph) |
|
|
Lapatinib
Target |
Targeted Therapy - Traditional small molecules
-Receptor Tyrosine Kinase Inhibitor -Target: Epidermal GF |
|
|
Bevacizumab
Target |
Targeted Therapy - Monoclonal Antibody
-Target: VEGF |
|
|
Gemtuzumab ozogamicin
Target |
Targeted Therapy - Monoclonal Antibody
Target: CD33 |
|
|
Rituximab
Target |
Targeted Therapy - Monoclonal Antibody
-Target: CD20 |
|
|
Ibritumomab Tiuxetan
Target |
Targeted Therapy - Monoclonal Antibody
Target: CD20 |
|
|
Atripla
General info |
Anti-Retroviral Drug
-Co-formulated, for one pill and once daily dose -NRTI (TDF & FTC) + NNRTI (EFV) |
