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11 Cards in this Set
- Front
- Back
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What are the 3 popular subclasses of penicillins?
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Natural, methicillin, and aminopenicillins
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What are the specific drugs under natural PCN?
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Pcn-G (IV)
Pcn-VK (PO) Bicillin (IM) |
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List the common bacterias that are PCN sensitive.
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STREP:
- pneumo - pyogenes - bovis - viridans Syphilis (T. palladum) Gangrene (C. perfringens) |
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What is the Mcc ADR of the PCNs?
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hypersensitivity
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What are the specific drugs under Methicillins?
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Naf- (IV) neutropenia
Oxa - (IV) hepatotoxic Cloxa- Dicloxa- *Penicillinase-resistant PCN* |
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List the common bacterias that are Methicillin sensitive.
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Strep, Staph, Enterococcus
STAPH: - cellulitis SSTI - IVDU endocarditis (Naf-, Gent-) - Osteomyelitis (Naf-) - Septic arthritis - Imgetigo. |
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What are the mode of clearance and ADR of Naf- and Oxa-?
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Naf - clear by biliary excretion (no renal dosing needed)
Oxa - cleared renally. |
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What are the specific drugs under AminoPCN?
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Ampicillin and Amoxicillin
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How are Amp- dosed?
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Ampicillin
250-500mg q6hr PO 1-2g q6hr IV Unasyn (Amp/Sulbactam): 1.5-3g q6hr |
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How are Amox- dosed?
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Amoxicillin
250-1g TID PO Augmentin (Amox/clavulanic) 500/125 PO TID 875/125 PO BID |
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List the common bacterias that are aminoPCN sensitive.
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Strep, Staph, L. mono
E. coli (30% resist) H. influ (30% resist) |
