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101 Cards in this Set
- Front
- Back
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Which of the following could you weight on a Class 3A torsion balance (ones used for prescription preparation in pharmacies)?
a. 10 mg b. 50 mg c. 75 mg d. 100 mg e. 200 mg |
e. 200 mg
Must be over 120 mg to avoid errors of 5% or more |
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Granules
a. require a smaller mesh size # sieve then fine powders b. have greater surface area than fine powders c. are the preferred drug formulation for incorporation into suppositories d. only used for the preparation of divided papers e. have greater reactivity with water as compared to fine powders |
a. require a smaller mesh size # sieve then fine powders
Mesh size # sieve is inversely proportional to the size of the opening of the screen per inch |
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Granule mesh size ranges from
a. 1-100 mesh b. 4-10 mesh c. 1-20 mesh d. 50-70 mesh |
b. 4-10 mesh
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When two areas of the skin touch this is referred to as
a. intertriginous b. intratrigunous c. insufflation d. slugs |
a. intertriginous
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Insufflation application deals with
a. tablets b. suppositories c. dusting powders d. liquids |
c. dusting powders
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Which of the following neutralizes electrostatic charges
a. sodium lauryl sulfate b. zinc oxide c. magnesium stearate d. talc |
a. sodium lauryl sulfate
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The definition of communition is
a. Increasing particle size of a finer state to a solid substance b. Reducing particle size of a solid substance to a finer state of subdivision c. Mixing a drug to evenly disperse drug d. To improve adherence of the drug |
b. Reducing particle size of a solid substance to a finer state of subdivision
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What is an appropriate size of particles for inhalation?
a. 1-4 g b. 60-80 microns c. 100-120 microns d. 1-3 mg e. 1-5 microns |
e. 1-5 microns
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Which of the following is a TRUE statement?
a. To avoid errors of 5% or more on a Class III (A) balance with a measured sensitivity requirement of 5 mg, do not weigh less than 120 mg of any drug or chemical. b. To avoid errors of 5% or more on a Class III (A) balance with a measured sensitivity requirement of 8 mg, do not weigh less than 160 mg of any drug or chemical. c. To avoid errors of 5% or more on a Class III (A) balance with a measured sensitivity requirement of 12 mg, do not weigh less than 360 mg of any drug or chemical. d. To avoid errors of 5% or more on a Class III (A) balance with a measured sensitivity requirement of 6 mg, do not weigh less than 60 mg of any drug or chemical. |
b. To avoid errors of 5% or more on a Class III (A) balance with a measured sensitivity requirement of 8 mg, do not weigh less than 160 mg of any drug or chemical.
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Which of the following is FALSE regarding segregation of particles:
a. Smaller particles migrate to the top while larger particles migrate to the bottom b. Particles that are denser tend to migrate to the bottom c. Only size and density impact segregation d. In order to decrease segregation, the shape of all the particles should be similar e. Electrostatic interactions can impact on segregation |
c. Only size and density impact segregation
Shape can also affect |
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Which of the following statements regarding mortars and pestles is false?
a. Ceramic mortars and pestles are appropriate to use when mixing potent drugs. b. Because porcelain mortars and pestles are porous, they should not be used with ingredients that stain. c. The mortar and pestle are made of three types of materials: glass, Wedgewood, or porcelain. d. Wedgewood is generally reserved for grinding hard powder particles, and porcelain is used for pulverizing soft aggregates or crystals. e. Glass mortars and pestles are preferable for mixing liquids and semisolid dosage forms. |
a. Ceramic mortars and pestles are appropriate to use when mixing potent drugs.
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Of the following method for preparation of powders, which one involves blending in a figure “8” motion to reduce particle size?
a. Trituration b. Tumbling c. Geometric dilution d. Spatulation e. Sifting |
d. Spatulation
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What is the minimum weighable quantity to prevent inaccuracy?
a. 0.05 grams b. 0.05 mg c. 120 mg d. 20 mg e. 120 gr |
c. 120 mg
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All of the correct procedures were done in the preparation of the blended powder for the capsule fill. Upon setting it was noted that the hydrochlorothiazide powder settled to the bottom of the container. Which of the following is the most likely reason for this segregation?
a. Difference in surface tension of the particles b. Difference in viscosity of the powders c. Difference in melting point of the ingredients d. Difference in the molecular weight of the compounds e. Difference in particle size |
e. Difference in particle size
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True or False. If a # 3 sized capsule was used instead of the # 1 sized capsule, the total amount lactose would decrease for the prescription.
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True
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True or False. A graduate cylinder that is designated TC would contain a larger volume of liquid than one designated TD when filled to the same 50 ml mark on the container.
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False
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The process of determining particle size is known as?
a. Intervention b. Dissolution c. Punching d. Levigation e. Sieving |
e. Sieving
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Which of the following would be the best for blending the powders together?
a. Levigation using a Wedge Wood Mortar and Pestle b. Trituration using a Glass Mortar and Pestle c. Triuration via geometric dilution with a Wedge Wood Mortar and Pestle d. Trituration using pile tile and metal spatula e. Mixing with via the addition of ethanol |
b. Trituration using a Glass Mortar and Pestle
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True or False. If a # 0 sized capsule was used instead of the # 1 sized capsule, the
total amount lactose would decrease for the prescription. |
False
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Which of the following is NOT a process for particle size reduction?
a. Comminution b. Trituration c. Pulverization by intervention d. Levigation e. Spatulation |
?
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Which of following is best described by this description? Applied to intertriginous areas as a covering to protect the skin from chafing of friction and moisture
a. Dusting Powders b. Granules c. Insufflation Powders d. Dentrifrices e. Polyox |
a. Dusting Powders
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Which of the following methods is the most accurate way to divide powder mixtures into unit doses?
a. Weighing each powder b. Blocking and dividing c. Powder measures d. Volumetric template |
a. Weighing each powder
Most time consuming however |
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The following Rx was compounded on Dec 1, 2007 with USP ingredients and triturated Lipitor powder.
What “Beyond Use Date” would be correct for the compounded prescription? a. Jan 2008 b. Feb 2008 c. June 2008 d. Dec 2008 e. Dec 2009 |
c. June 2008
6 months if prepared from USP/NF ingredients 25% of expiration date remaining if prepared from commercial products |
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True or False You would have to use an aliquot method in preparing this compound (uses 10 mg, 25 mg, and 0.5 mg) since there is a powder below the minimum weighable quantity in the procedure.
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True
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Substances which absorb moisture from the air to the extent to liquefy by forming a solution is known as
a. lipophilic b. hygroscopic c. deliquescent d. volatile e. efflorescent |
c. deliquescent
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Crystalline substances which become powdery and liberate their water of crystallization include
a. volatile b. hygroscopic c. efflorescent d. deliquescent e. imbibtion |
c. efflorescent
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Which of the following is NOT an example of a eutectic?
a. phenol b. aspirin c. camphor d. terpin hydrate e. choral hydrate f.thymol |
d. terpin hydrate
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Which of the following correctly describes efflorescent powders?
a. They absorb moisture to form a solution. b. They absorb moisture but do not form solution. c. They become powdery by liberating their water of crystallization during trituration d. If not stored correctly can lead to dosing errors in compounding e. none of the above are correct |
d. If not stored correctly can lead to dosing errors in compounding
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If you have an efflorescent powder and do not recognize it, you are most likely to:
a. Overdose the patient b. Underdose the patient c. Make the dosage form taste bad d. Make the dosage form smell bad e. Create an polymorph |
a. Overdose the patient
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Which of the following would be part of a eutectic mixture?
a .Ferrous sulfate b. Citric acid c. Menthol d. Calcium Lactate e. All of the above |
c. Menthol
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What is the difference between swelling and imbibition?
a. swelling is the reversible transformation from gel to liquid. b. swelling is the taking up of a certain amount of liquid without a measurable increase in volume. c. imbibition is when the gel shrinks. d. swelling is the taking up of liquid with an increase in volume. |
d. swelling is the taking up of liquid with an increase in volume.
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An effervescent granule would contain a mixture of citric acid
a. with folic acid and API b. with bicarbonate and API c. with sodium biphosphate and API d. with tartaric acid and API |
b. with bicarbonate and API
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What year was the soft gelatin capsule developed?
a. 1833 b. 1834 c. 1846 d. 1848 e. 1945 |
a. 1833
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What is the rate limiting step for capsules with a low solubility drug?
a. Gelatin shell b. Packed powder particles c. Solution of drug d. Stomach emptying time |
c. Solution of drug
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What is the rate limiting step for capsules with a high solubility drug?
a. Gelatin shell b. Packed powder particles c. Solution of drug d. Stomach emptying time |
b. Packed powder particles
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What is the typical capsule size for human consumption?
a. 000-2 b. 3-5 c. 0-2 d. 000-0 |
c. 0-2
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1.What is the correct order of the first 3 steps in capsule preparation?
a. Determine capsule size, blending, comminution b. Blending, determine capsule size, comminution c. Comminution, blending, determine capsule size d. Blending, comminution, determine capsule size e. None of the above |
c. Comminution, blending, determine capsule size
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1.When compounding effervescent granules which of the following is FALSE:
a. usually contain a mix of citric or tartaric acid with a medicinal agent b. the vehicle is a contains sodium hydroxide to activate the acid c. Lessens the salty/bitter tastes of different inorganic salts d. It gives the patient a pleasant taste e. all of the above are False |
b. the vehicle is a contains sodium hydroxide to activate the acid
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Which of the following is true about compounded capsules?
a. Type A gelatin is derived mainly from pork skins and produced by alkaline hydrolysis. b. Type B gelatin is obtained from bones and animal skins by acid hydrolysis. c. Capsules are protected from the effects of relative humidity and microbial contamination. d. The range of hard gelatin capsule sizes can hold approximately 40 mg to 1.5 g of powdered material. |
d. The range of hard gelatin capsule sizes can hold approximately 40 mg to 1.5 g of powdered material.
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Which excipient would be useful in the removal of fingerprints from the capsule?
a. Sugar b. Gelatin c. Sulfur dioxide d. Sodium chloride e. Glycerin |
d. Sodium chloride
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What type of capsule form would the following prescription produce?
Estriol 200 mg Estrone 25 mg Estradiol 25 mg Polyethylene glycol 1450 20 g Polyethylene glycol 3350 20 g a. Powder Filled Capsule b. Semisolid Filled Capsule c. Liquid Filled Hard Gelating Capsule d. Liquid Filled Soft Gelating Capsule e. Delayed Release Capsule |
b. Semisolid Filled Capsule
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Which excipient is used to make Sustained release capsules?
a. Methylcellulose b. Corn starch c. Cellulose acetate phthalate d. Sodium chloride e. PEG 1450 |
a. Methylcellulose
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Which of the following excipients would be found in an effervescent tablet formulation
but not a regular capsule formulation? a. Lactose b. Citric Acid c. Sodium dodecylsulfate d. Dextrose e. Stevia |
b. Citric Acid
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Which excipient is used to make DELAYED release capsules?
a. Methylcellulose b. Corn starch c. Cellulose acetate phthalate d. Sodium alginate e. PEG 1450 |
c. Cellulose acetate phthalate
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Which of the following would not be found in the gelatin capsules for the prescription?
a. Sugar b. Gelatin d. Sulfur dioxide e. Water f. Glycerin |
f. Glycerin
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During the preparation of the capsules the powder clumped together. What is the most reasonable explanation for this event?
a. The formation of an eutectic b. An efflorescent powder c. A hydroscopic powder d. A deliquescent powder e. A polymorphic change |
c. A hydroscopic powder
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Molded tablets are made by molding a soft mass which usually consists of a potent medication
a. diluted with lactose and moistened with dextrose b. diluted with water and moistened with lactose c. diluted with alcohol and moistened with lactose d. diluted with lactose and moistened with alcohol |
d. diluted with lactose and moistened with alcohol
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Which of the following is False for Lubricants?
a. Improve powder flow properties b. Decrease adhesion to punch/die c. Decrease friction to punch/die d. Facilitate tablet ejection e. Increase punch/die wear |
e. Increase punch/die wear
Reduce punch/die wear |
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In sintered tablets, to create meltable binder and make the tablet waxy, one would use:
a. freeze-dry b. fusion c. liquidation d. compression to solid |
b. fusion
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Which of the following is a natural sweetner?
a. Fructose b. Sucrose c. Stevia d. PEG |
c. Stevia
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Why are lubricants used in the making of compressed tablets?
a. Hold powdered materials together b. Aid in breaking up the tablet after ingestion c. Decrease friction between tablet and punch/die d. Increase friability e. All of the above are reasons lubricants are used |
c. Decrease friction between tablet and punch/die
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Which of the following is FALSE about lozenges?
a. They have traditionally been used for local effects to administer topical anesthetics and demulcents b. The common practice today is to use them to deliver some drugs systemically. c. They are useful for patients who have difficulty swallowing oral solid dosage forms d. They are always made from compression methods e. They are useful for medications that give maximum benefit when in prolonged contact with local tissues |
d. They are always made from compression methods
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Which excipient is found in the preparation of molded tablets but not hard gelatin
capsules? a. Ethanol b. Sodium dodecylsulfate (SDS) c. Glycerin d. Tracer dye e. Lactose |
a. Ethanol
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What excipient is missing from the molded sintered tablet formulation below?
Sodium Fluoride Sodium fluoride Sucrose, powdered Lactose, hydrous Makes #100 tablets a. Avicel b. Ethanol c. Glycerin d. Mineral Oil e. PEG |
e. PEG
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Which of the following statements is FALSE for Acaica?
a. Is a synthetic polymer b. Can absorb twice its weight in water c. Can be used as a thickening agent d. Can be used in Troche compounding e. Can be used in Lozenge Compounding |
a. Is a synthetic polymer
Natural |
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Which of the following is False?
a. The rectum can hold 2-3 mL of fluid b. The rectum has buffer capacity c. pH of the rectum is 6.5-7.5 d. Upper rectum has more of a first pass effect e. Unionized drug is absorbed more than ionized drug in the rectum |
b. The rectum has buffer capacity
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Which of the following is false regarding Polyethylene Gylcol Suppository Bases?
a. Polymers of varying molecular weights b. Water soluble c. Relatively high melting points d. Stable (except with aspirin) e. Dissolve in body fluids |
c. Relatively high melting points
Relatively low melting points |
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Which of the following is a special problem for suppositories?
a. Hard, crystalline materials b. Too little powder c. Non-liquid ingredients d. Non-vegetable extracts |
a. Hard, crystalline materials
Abrasive and dense particles will settle more |
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Which of the following is NOT part of quality control testing procedures for suppositories?
a. Breaking Testing b. Melting Range Testing c. Softening/Liquefaction Temperature Testing d. Liquefaction Time Testing e. All of the Above are part of QC Testing |
e. All of the Above are part of QC Testing
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Which suppository base & examples are correctly matched?
a. oleaginous : hydrophilics b. oleaginous : gelatin c. water-soluble : cocoa butter d. water-soluble : PEG |
d. water-soluble : PEG
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1.Solid dosage forms that are used to administer medication via the rectum, vagina or urethra are known as
a. Suppositories b. Pills c. Lozenges d. Troches e. None of the above |
a. Suppositories
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What effect do vegetable extracts have on the melting temperature of cocoa butter suppositories?
a. Raise the melting temperature b. Lower the melting temperature c. Have no effect on the melting temperature d. Impossible to tell what would happen to the melting temperature. e. None of the above. |
b. Lower the melting temperature
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1.In general you can't put more than what percentage of drug into a suppository base?
a. 90% b. 70% c. 50% d. 30% e. 10% |
d. 30%
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Which of the following are False?
a. Oil soluble drugs have a fast release in an oily base. b. Water soluble drugs have a fast release in an oily base. c. Oil soluble drugs have a fast release in a water miscible base. d. A&B e. B & C |
a. Oil soluble drugs have a fast release in an oily base.
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1.Which of the following suppositories can contain the greatest mass?
a. Bougie b. Urethral suppository c. Vaginal suppository d. Rectal Suppository e. Both A and C |
c. Vaginal suppository
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Which of the following is FALSE of PEG Rectal Suppositories?
a. Can be useful for patients who can not receive parenteral injections b. Are most often compounded with the use of fusion c. Release their drugs through dissolution d. Useful for patients with nausea e. Are less irritating to mucosa tissues then oleaginous suppositories |
e. Are less irritating to mucosa tissues then oleaginous suppositories
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Which of the following is a process for suppository preparation?
a. Comminution b. Fusion c. Pulverization by intervention d. Levigation e. Spatulation |
b. Fusion
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What is the major advantage of Fatty Acid Base (Synthetic Triglyceride Mixtures) over Cocoa Butter as a suppository base?
a. Fatty acid base dissolves and can be used for both hydrophilic and lipophilic drugs b. Fatty acid base is a liquid that solidifies upon addition of calcium chloride solution c. Cocoa butter has polymorphic forms make compounding difficult d. There are fewer allergies with Fatty acid base as compared to cocoa butter e. Fatty acid Base has a density replacement factor or 1 making it easier to use in compounding compared to the density replacement factor of 0.6 for cocoa butter |
c. Cocoa butter has polymorphic forms make compounding difficult
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Dyes can be added to all of the following compounded prescriptions EXCEPT?
a. Syrup b. Tablet c. Capsule d. Suppository e. Troche |
d. Suppository
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True or False. In compounding a PEG suppository the pharmacist calculates the displacement factor of a drug is 1. This means the drug will displace the same amount of PEG suppository base during suppository formulation.
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True
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Match the correct Olegainous Bases to examples
a. Hydrocarbons: Isopropyl lanolate b. Animal/vegatable fats/oils: Paraffins c. Synthetic esters: Waxes d. Hydrocarbon: Castor oil e. Synthetic ester: Cetyl alcohol |
e. Synthetic ester: Cetyl alcohol
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Which of the following are the characteristics of a water-in-oil emulsion base?
a. Water soluble, Not washable in water, Can absorb water, Contains no water b. Water soluble, Washable in water, Can absorb water, Contains water c. Water insoluble, Washable in water, Can able water, Contains water d. Water insoluble, Not washable in water, Can absorb water, Contains water |
d. Water insoluble, Not washable in water, Can absorb water, Contains water
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Which of the following is not a humectant?
a. lanolin b. glycerin c. propylene glycol d. sorbitol 70% e. all of the above are humectants |
a. lanolin
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Which is false regarding Creams?
a. Opaque b. Soft Solids c. Non- Viscous d. Won't flow under force of gravity |
c. Non- Viscous
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Which statement is correct regarding the definition of a lotion?
a. Thick, stiff ointments that do not flow at body temperature and serve as protective coatings over the areas to which they are applied. b. Semisolid preparations for external use to soften or melt at body temperature. c. Aqueous preparations with insoluble material for external application without friction. d. Viscous liquids or semisolid emulsions of either O/W or W/O type. e. Solid or semisolid preparations which cannot be spread at room temperature. |
c. Aqueous preparations with insoluble material for external application without friction.
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Which of the following is/are FALSE?
a. Plasters are solid of semisolid preparations that cannot be spread at room temperature. b. Cerates are preparations containing a relatively high wax content. c. Creams are good for application to moist, weeping lesions. d. Ointments can soften or melt at body temperature. e. All of the above statements are true. |
e. All of the above statements are true.
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1.Which of the following is/are true?
A. Polyethylene glycol has humectant properties, making it ideal as a desiccating agent B. “W/O emulsion” refers to oil droplets suspended in an aqueous solution. C. Lanolin is referred to as hydrous wool fat D. White petrolatum and white ointment are examples of oleaginous bases E. When compounding with varying MW PEGs, melt them starting with the lowest MW and blend in the higher MW PEGs. a. Statements A, B, and C are correct b. Statement D only is correct c. Statements C, D, and E are correct d. Statement B only is correct e. Statements C and D are correct |
e. Statements C and D are correct
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Which of the following statements below is correct?
a. Colloids pass through a semi-permeable membrane. b. Adding viscosity enhancers to suspensions increases the sedimentation rate. c. Instabilities that occur with emulsions include creaming, coalescence, and phase inversion. d. Blending is the process of reducing the size of particles or aggregates. |
c. Instabilities that occur with emulsions include creaming, coalescence, and phase inversion.
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A semisolid topical medication that retains its configuration, but flows with little pressure has ________ flow characteristics:
a. plastic b. dilatant c. pseudoplastic d. newtonian |
c. pseudoplastic
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Which of the following is true about ointment preparation:
a. Heat lowest melting point material first b. W/O - add oil slowly c. O/W - add water slowly d. All of the above are true e. All of the above are False |
e. All of the above are False
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The biggest barrier for transdermal formulations is passage through
a. The Epidermis b. The Basal Cell Layer c. The Stratum Corneum d. The Stratum Granulosum e. The Reticular Layer |
c. The Stratum Corneum
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What is the oil:water:acacia ratio for a primary acacia emulsion?
a. 3:2:1 b. 4:4:2 c. 4:2:1 d. 2:3:2 |
c. 4:2:1
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Which of the following base/active ingredient property combinations will provide a fast-release suppository?
a. oil base/oil soluble active ingredient b. oil base/water soluble active ingredient c. water base/water soluble active ingredient d. water base/oil soluble active ingredient e. both B & D |
e. both B & D
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Which of the following is would be a good levigating agent that can be used in an oleaginous base?
a. Propylene Glycol b. Potassium metabisulfate c. Mineral Oil d. Butylated hydroxyanisole (BHA) e. Citric Acid |
c. Mineral Oil
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Which of the following is typically used as a levigating agent?
a. Benzyl Alcohol b. Sodium Dodecylsulfate c. PEG 3000 d. Glycerin e. Acacia |
d. Glycerin
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What would be the BEST levigating agent for the following prescription?
Sodium Chloride 5% White Petrolatum qs 1 oz a. ethanol b. water c. glycerin d. mineral oil e. propylene glycol |
d. mineral oil
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Which of the following is an example of a hydrocarbon organogel?
a. Petrolatum b. Carbowax base c. Plastibase d. PEG ointment e. A and C f. B and D |
e. A and C
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1.Which definition of the phenomena associated with gels is correctly defined?
a. Swelling - The taking up of a certain amount of liquid without a measurable increase in volume b. Imbibition - The taking up of a liquid by a gel with an increase in volume. c. Syneresius - Reversible gel-sol formation with no change in volume or temperature d. Thixotropy - Interaction between particles of the disperesed phase is great so that the dispensing medium is squeezed out in droplets and the gel shrinks. e. None of the above, they are all wrong. |
e. None of the above, they are all wrong.
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Which of the following describes Syneresis?
a. When the interaction between particles of the dispersed phase becomes so great that on standing, the dispersing medium is squeezed out in droplets and the gel shrinks. b. The taking up of liquid by a gel with an increase in volume. c. The taking up of a certain amount of liquid without a measurable increase in volume. d. A reversible gel-sol formation with no change in volume or temperature. e. None of the above |
a. When the interaction between particles of the dispersed phase becomes so great that on standing, the dispersing medium is squeezed out in droplets and the gel shrinks.
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Which of the following is a natural polymer?
a. Methylcellulose b. Poloxamer c. Tragacanth d. Silicone dioxide e. Carbomer |
c. Tragacanth
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Estradiol Topical Gel contains estradiol, 70% isopropyl alcohol, carbormer 940, triethamolamine, & purified water. Which of the ingredients in this preparation is the gelling agent?
a. 70% isopropyl alcohol b. carbormer 940 c. estradiol d. purfied water e. triethanolamine |
b. carbormer 940
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Which of the following is false regarding beyond-use dating?
a. The beyond-use dating should be no later than 14 days in water-containing formulas stored at a cold temperature. b. The beyond-use dating can be exceeded if valid supporting stability information is available for the specific preparation. c. If the source of a non-aqueous liquid or solid is a USP or NF substance, the beyond-use date is no later than 6 months. d. If the source of a non-aqueous liquid or solid is a manufactured drug product, the beyond-use date should be no later than 50% of the time remaining on the original product’s expiration or 6 months (whichever is earlier). |
d. If the source of a non-aqueous liquid or solid is a manufactured drug product, the beyond-use date should be no later than 50% of the time remaining on the original product’s expiration or 6 months (whichever is earlier).
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What is the reason/agent that induces Carbomer to gel or increase viscosity?
a. Calcium ions b. Alkaline pH c. Increase in temperature d. High humidity e. Polymorphic change |
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Which of the following is true?
a. Elixirs contain alcohol. b. Glycerin can increase cap lock c. Increasing viscosity will increase the sedimentation rate. d. Decreasing the particle size will increase the sedimentation rate. e. Simple syrup USP requires preservatives. |
a. Elixirs contain alcohol.
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During the preparation of the capsules the powders were sticking to each other and all of the compounding equipment. This problem could be addressed by the addition of?
a. Silica gel b. PEG 400 c. Stevia d. Sodium dodecylsulfate e. Ethanol |
d. Sodium dodecylsulfate
Not sure if discussed? |
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How much PEG base would be required for the following prescription?
Progesterone 200 mg PEG Base qs M & ft Suppositories #10 Sig Insert 1 supp vaginally ut dict for PMS Information: Density of progesterone 0.67 g/ml, Density of PEG Base 0.9 g/ml Weight of a Blank Suppository 1.9 g, weight of a medicated suppository 1.75 g a. 7.8 g b. 8.6 g c. 9.4 g d. 10.7 g e. 15.5 g |
e. 15.5 g
DF = B/(A-C+B) (A=blank, B= weight of drug, C= medicated suppository) |
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A prescription requires 10 ml of a 2 % lidocaine (mw 234) solution but the pharmacist only has lidocaine HCl (mw 288) in stock, how many milligrams of lidocaine HCl should be used?
a. 81 mg b. 123 mg c. 163 mg d. 246 mg e. 535 mg |
d. 246 mg
W = ab/de |
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How many mLs of a 40% ethanol solution would you added to 100 ml of a 80% ethanol solution to make a finial concentration of 70%?
a. 25 mL b. 33 mL c. 50 mL d. 18.5 ml e. 27.5 ml |
b. 33 mL
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You have 5 ml of tobramycin ophthalmic solution 0.2%. You dilute it with 1 mL of sterile saline solution. What is the percent strength of tobramycin in the final solution?
a. 0.13 b. 0.15 c. 0.17 d. 0.19 e. 0.2 |
c. 0.17
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If a Rx class for the preparation of 10 ml of 1% lidocaine (mw 234) but for the purposes of solubility the pharmacist has lidocaine HCl (mw 288) how many milligrams should be used?
a. 81 mg b. 123 mg c. 243 mg d. 369 mg e. 535 mg |
b. 123 mg
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How much PEG base would be required for the following prescription?
Progesterone 200 mg PEG Base qs M & ft Suppositories #6 Sig Insert 1 supp vaginally ut dict for PMS Information: Density of progesterone 0.67 g/ml, Density of PEG Base 0.9 g/ml Weight of a Blank Suppository 1.9 g, weight of a medicated suppository 1.75 g a. 9.4 g b. 11.4 g c. 7.8 g d. 10.7 g e. 8.6 g |
a. 9.4 g
DF = B/(A-C+B) (A=blank, B= weight of drug, C= medicated suppository) |
