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38 Cards in this Set
- Front
- Back
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dry powder inhalers dispense a powder in a stream of ---- air
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inspired
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the force of powder flow comes from ---- effors of the pt in DPI's
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inspiratory
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the drug formulation ofr powder is USUally the drug plus a ---- powder
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carrier
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the powder drug must be ---- to the proper size
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micronized
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if too small what can happen to the powder
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more cohesive
and adhesive they can stick to each other and the device |
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which is larger the carrier or the drug
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carrier
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fx of carrier powders:
improve powder ---- and ----- |
flow
dispersability |
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ex of carrier powders
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lactose
glucose |
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when inhaled what comes off?
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smaller particles
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since larger particle are larger, they will be less --------
so, what happens to them |
respirable
they will impact and be swallowed |
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t/f
DPI's are unit dose |
f
either unit or multiple |
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in unit dose the drug formulation is ------ in hard ---- capsules and loaded into the device
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prefilled
gelatin |
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in the ---- the capsule is broken open in the device and the powder is inhaled thru a screened tube
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rotahaler
ex: ventolin |
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in the ROTAHALER the capsule is broken open in the device and the powder is inhaled thru a ----- tube
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screened
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in the HANDIHALER the capsule is ------ on the SIDE in the device and the powder is inhaled thru a ---- tube
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punctured
screen ex. spriva |
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in AEROLIZER the capsule is punctured on ---- ---- in the device and the powder is inhaled thru a ---- tube
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each end
foradil aerolizer |
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ex of multi unit doses
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diskhaler
diskus |
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these have several UNIT doses loaded into the devoce
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multiple unit-dose DPI's
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DISKHALER contains a --- disk that contains powder ----- separately packed in ---- blister packs
they are --- before inhalation powder |
circular
charges aluminum pierced |
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ex of unit dose DPI's
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Rotahaler
Handihaler Aerolizer |
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in DISKUS powders (drug plus lactose) are contained w/in --- strip w/ each blister containing a dose that is inhaled after --- by the patient
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blister
activation ex: advair serevent |
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multiple dose DPI's have a ---- of drug, from which doses are ---- into an inhalation chamber
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reservoir
metered |
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ex of multi dose DPI's
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pulmicort flexhaler
asmanex twisthaler |
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pulmicort flexhaler is a --- ---powder delivery system
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metered dose
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---- budesonide pulse micronized ---- is conatained w/in a storage reservoir
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micronized
lactose |
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when giving pulmicort how do you know the med is ready to be given
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twist until you hear a clicking sound
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t/f
pulmicort flexhaler comes in two doses |
t
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does pulmicort have individual doses in the reservoir
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no
it's a reservior of drugs: draw dose from bulk |
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this is micronized momestasone furoate plus lactose is contained w/in a storage reservoir
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asamanex twisthaler
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how do you prepare asmanex before adminstering
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twist then pull off cap
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shelf life for asmanex
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45 days after opening
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asmanex is packaged in an ---- pouch
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impervious
so after opening there's a change in shelf life moisture sorption |
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dispersion of drug from it's agglomeration depends on the ---- of the --- flow
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energy
inspiratory |
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sufficient ---- flow is necessary to ----- and inhale powder particles and to inhale sufficient dose of the drug
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inspiratory
deaggregate prob: not all pt's are capable of this |
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different devices have different --- to inspiratory flow
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resistance
thus, differences inhalation force required |
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---- --- can increase particle size and can decrease the ability of the agglomerate to -----
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moisture sorption
deagglomerate |
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moisture sorption decreases the amount delivered to the -----
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lung
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which is more sensitive to high humidity than diskus
why |
flexhaler
cuz it has a reservoir of drug, whereas diskus has each dose packaged |
