Dosage 2, Other Advanced Drug Delivery, Final

Front 1

eye med that's biodegradable

Back 1

lacrisert

Front 2

what do you place lacrisert

Back 2

cul-de-sac

Front 3

after the lacrisert imbibes water what does it form

Back 3

gell like mass

Front 4

when does the gel like mass dissolve

Back 4

when the polymer dissolves

Front 5

the gel like mass lubricates the eye for how long

Back 5

14-18 hrs

Front 6

what's the lacrisert used for

Back 6

severe dry eye syndrome

Front 7

t/f

w/ lacrisert you have to place eyedrops frequently

Back 7

f

Front 8

two types of opthalmic meds

Back 8

biodegradable matrix

membrane controlled intravitreal implant

Front 9

how is the membrane controlled intravitreal implant kept in place

where

Back 9

sutured w/in POSTERIOR segment of the eye

Front 10

name a membrane controlled intravitreal implant

Back 10

retisert

Front 11

retisert consists of a --- encased in a silicone elastomer cup containing a release orifice and a ---- alcohol membrane positioned between the tab and the orifice

Back 11

tablet

polyvinyl

Front 12

what's retisert for?

is it biodegradable?

hwo long will it last

Back 12

uveitis

not biodegradable

for about 30 MONTHS

Front 13

t/f

retisert is invasive

Back 13

true

Front 14

how is vitrasert different form retisert?

Back 14

is contains ganciclovir

Front 15

what vitrasert used for

Back 15

CMV in AIDS

Front 16

is vitrasert biodegradable

Back 16

no

Front 17

vitrasert has a steady release of -- to -- months

Back 17

5-8 MONTHS

Front 18

types of IUD's

Back 18

copper

hormonal

Front 19

mirena is a --- controlled reservoir IUD

Back 19

membrane

Front 20

what order is mirena

Back 20

zero order

Front 21

this IUD has steady release for 5 yrs

Back 21

levonorgestrel (MIRENA)

Front 22

types of intravaginal

Back 22

swellable matrix

mucoadhesive gels

membrane controlled reservoir

Front 23

name a swellable matrix med

Back 23

cervidil

Front 24

cervidil is a ---- inserted w/in a ---- ---- system

Back 24

hydrogel

knitted retrieval

Front 25

how does cervidil work

Back 25

absorbs water, then releases PGE2 for 2 hrs

Front 26

labor inducing med

Back 26

cervidil

Front 27

ex of mucoadhesive gels

Back 27

progesterone

Front 28

progesterone formulated into a polycarbohphil gel: ---- charges allows attachment to mucous of vag epithelium

Back 28

negative

Front 29

progesterone gels has steady drug release from ------- EMULSION

Back 29

oil/water

Front 30

what's progesterone gel used for

Back 30

local uterine action to aid embryo emplantation

Front 31

ex of membrane controlled reservoir

what order

Back 31

vaginal rings

zero order

Front 32

these are flexible rings inserted vaginally and left in place for various time periods

Back 32

vaginal rings

Front 33

nuvaring a drug reservoir 2 estrogens is contained w/in a ---- ring

Back 33

polymer

Front 34

this estradiol ring is inserted into the upper 1/3 of vagina

Back 34

estring

Front 35

estring has intial (fast/slow) followed by ---- release for 3 monts

Back 35

fast

steady

Front 36

femring is for ----

Back 36

menopause

Front 37

two peridontal meds

Back 37

atridox

actisite

Front 38

atridox is a -- syringe system, where doxycyline in one syringe mixed w/ ---- soln in another syringe

Back 38

2

poly

Front 39

t/f

atridox is solid prior to infecting

Back 39

f

you inject it first then it becomes solid

Front 40

where is atridox injected

Back 40

peridontal pocket

Front 41

t/f

atridox is biodegradable

Back 41

t

Front 42

what does atridox degrade to

Back 42

lactic acid

Front 43

atridox is CR for -- days

Back 43

7 days

Front 44

actisite is tetracycline in as ethylene/vinyl acetate ---- fiber

Back 44

copolymer

Front 45

t/f

the fiber in actisite is biodegradable

Back 45

f

nonbiodegradable

Front 46

where are the fibers of actisite place

Back 46

peridontal pocket

Front 47

steady tetracycline relelae for

Back 47

10 days