Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
30 Cards in this Set
- Front
- Back
|
DNA can replicate its self with accuracy |
True |
|
|
DNA contains information by how ? |
Having specific sequences of bases |
|
|
Inborn born errors of metabolism are |
Mutations in a single gene |
|
|
One gene, |
One protein |
|
|
A |
T |
|
|
C |
G |
|
|
Hershey and chase were known for |
Transduction experiments: viral DNA was injected into the host cell |
|
|
Watson and crick are know for ? |
Double helix model Base pairs C G 3 hydrogen bonds AT 2 hydrogen bonds 2 strands of DNA being antiparallel |
|
|
Serves as a template for DNA |
Existing DNA |
|
|
DNA is what type of replication |
Semi conservative |
|
|
New strands are synthesized by complementary base parings |
AT CG |
|
|
Initiation |
Unwinding is DNA strands |
|
|
Initiation |
Unwinding is DNA strands Takes place in designated initiation sites |
|
|
Elongation |
Complementary base pairings DNA replication fork DNA polymerase is the elongation enzyme Energy source : high energy phosphate bonds from triphosphates Substrates dATP dTTP dGTP dCTP |
|
|
Termination |
Completing the process fixing mistakes splicing strands Ligase connects to Okazaki fragments Telomeres read the ends of chromosomes |
|
|
Helicase |
Enzyme involved in unpairing of bases |
|
|
Single stranded binding proteins |
Attach to umpaired DNA strand binding proteins Holds template DNA strand straight untill new complementary strand can be synthesized |
|
|
Single stranded binding proteins |
Attach to umpaired DNA strand binding proteins Holds template DNA strand straight untill new complementary strand can be synthesized |
|
|
Binding a primase to and imitation site forms |
an RNA primer 10 nucleotides |
|
|
S strain is |
Pathogenic |
|
|
R strain is |
Non pathogenic |
|
|
What is transformation |
The insertion of foreign bacterial DNA into a genome |
|
|
Purines |
A and G |
|
|
Purimidines |
C and T |
|
|
The covalent bonds found between two nucleotides in the same strand of a DNA molecule |
Hydrogen bonds |
|
|
How would you note the orientation of a DNA strand |
3’ —> 5’ |
|
|
What is exclusion repair |
Involves continual monitoring and repair of DNA Nuclease cuts out damaged segment DNA polymerase and ligase replace regent and connect it to its original strand |
|
|
Prokaryotes |
Single initiation site Can add 1000000 base pairs min Contain long stretches of unique DNA Circular no telomere problem Single DNA polymerase Only DNA polymerase function in mismatch repair |
|
|
Eukaryotes |
Multi initiation site 500 base pairs a min Repetitive DNA Telomere replication problems Several DNA polymerase Several proteins in addition to polymerase required for mis match repair |
|
|
What is a telomere |
The ends of a liner chromosome |
